(v. t.) To make loose; to free from tightness, tension, firmness, or fixedness; to make less dense or compact; as, to loosen a string, or a knot; to loosen a rock in the earth.
(v. t.) To free from restraint; to set at liberty..
(v. t.) To remove costiveness from; to facilitate or increase the alvine discharges of.
(v. i.) To become loose; to become less tight, firm, or compact.
Example Sentences:
(1) There is a gradual loosening of the adolescent's emotional dependence on her parents and a transfer of dependency ties to peers.
(2) The torques, although not large enough to dislodge the socket immediately, are repetitive and so may contribute to loosening.
(3) Femoral endosteal bone loss has been shown to be part of the natural aging process and may be a factor in femoral component loosening following total hip arthroplasty (THA).
(4) Seventeen of these were due to infection or loosening of the prosthesis.
(5) Loosening of the sutures and keratitis were the main complications in the postoperative course.
(6) Electric birefringence studies suggest that methylation may result in both interparticle cross-linking and some localised loosening of the DNA-protein complex complex.
(7) Two tibial components (2%) were believed to be mechanically loose, but no revisions for mechanical loosening were done.
(8) An artificial joint that articulates with full fluid film lubrication could greatly reduce wear and frictional torque and hence reduce the incidence of loosening and inflammatory tissue reaction.
(9) Aseptic loosening is the most common mode of failure for total knee replacements.
(10) The criteria of failure of pedicular instrumentation or "death" of an implant were defined as 1) screw bending, 2) screw breakage, 3) infection, 4) loosening of implants, 5) any rod or plate hardware problems, or 6) removal of hardware due to a neurologic complication.
(11) In the areas of disorganized collagen fibres cervical fibroblasts seemed to be activated characterized by fine granular loosening of the cytoplasma, dilated cisternae of rough endoplasmatic reticulum, vacuolized enlarged mitochondria and an increased number of cytoplasmatic vesicles close to the cell surface.
(12) Loosening of the tightly folded "native" structure of the two proteins following their synthesis in a rabbit reticulocyte lysate was assayed by the acquisition of protease sensitivity (pODHFR and pOCAT) or by the loss of enzyme activity (pOCAT).
(13) We concluded that the acetabular component of the Wagner prosthesis is prone to early loosening and that the early loosening is potentiated by a foreign-body response to debris resulting from arthroplastic wear.
(14) I think that is where we will see the most immediate loosening up of restrictions,” Handjani said.
(15) The reduction in the rate of aseptic loosening of the socket in our series, compared with the higher rates reported in similar long-term studies in which other acetabular components were used, supports the conclusion that there is enhanced longevity of acetabular fixation when a metal-backed acetabular component is used in cemented total hip arthroplasty.
(16) The loosening of such interactions is believed to induce conformational changes, which will alter ion transport systems necessary to the propagation of neural impulses.
(17) Main changes of upper compartments were showed on the bilaminar zone, including disc perforation and anterior displacement and capsular loosening.
(18) Significant problems included abnormal posture in the wrist, roentgenographic evidence of loosening in the finger metacarpophalangeals, extensor lag in the metacarpophalangeal of the thumb, and lack of motion in the proximal interphalangeal joint of the finger.
(19) China's government and media have launched a broadside against Japan's move to loosen the bonds on its powerful military, casting it as a threat to Asian security.
(20) However, because loosening and sinking of the prosthesis were significant, a ceramic total prosthesis was designed in 1980 to be used without cement.