(v. t.) The act of losing; failure; destruction; privation; as, the loss of property; loss of money by gaming; loss of health or reputation.
(v. t.) The state of losing or having lost; the privation, defect, misfortune, harm, etc., which ensues from losing.
(v. t.) That which is lost or from which one has parted; waste; -- opposed to gain or increase; as, the loss of liquor by leakage was considerable.
(v. t.) The state of being lost or destroyed; especially, the wreck or foundering of a ship or other vessel.
(v. t.) Failure to gain or win; as, loss of a race or battle.
(v. t.) Failure to use advantageously; as, loss of time.
(v. t.) Killed, wounded, and captured persons, or captured property.
(v. t.) Destruction or diminution of value, if brought about in a manner provided for in the insurance contract (as destruction by fire or wreck, damage by water or smoke), or the death or injury of an insured person; also, the sum paid or payable therefor; as, the losses of the company this year amount to a million of dollars.
Example Sentences:
(1) Tryptic digestion of the membranes caused complete disappearance of the binding activity, but heat-treatment for 5 min at 70 degrees C caused only 40% loss of activity.
(2) These studies, in addition to demonstrating that the placenta contains TRH deamidase activity, suggest that losses of fetal TRH through the placenta are not large.
(3) Our results indicate that increasing the delay for more than 8 days following irradiation and TCD syngeneic BMT leads to a rapid loss of the ability to achieve alloengraftment by non-TCD allogeneic bone marrow.
(4) Even with hepatic lipase, phospholipid hydrolysis could not deplete VLDL and IDL of sufficient phospholipid molecules to account for the loss of surface phospholipid that accompanies triacylglycerol hydrolysis and decreasing core volume as LDL is formed (or for conversion of HDL2 to HDL3).
(5) Histological studies of nerves 2 years following irradiation demonstrated loss of axons and myelin, with a corresponding increase in endoneurial, perineurial, and epineurial connective tissue.
(6) The stages of mourning involve cognitive learning of the reality of the loss; behaviours associated with mourning, such as searching, embody unlearning by extinction; finally, physiological concomitants of grief may influence unlearning by direct effects on neurotransmitters or neurohormones, such as cortisol, ACTH, or norepinephrine.
(7) Moreover, in DCVC-treated cells the mitochondria could not be stained with rhodamine-123, indicating severe mitochondrial damage and loss of membrane potential.
(8) Adenosine diphosphate (ADP) afforded significant protection only at the very highest concentration (5.0 mM); inorganic pyrophosphate (PPi) did not protect against loss of latency at any concentration.
(9) The west Africa Ebola epidemic “Few global events match epidemics and pandemics in potential to disrupt human security and inflict loss of life and economic and social damage,” he said.
(10) Thus, it appears that neuronal loss may account for up to roughly half of the striatal D2 receptor loss during aging.
(11) Hearing loss at 8 kHz would shorten the I-V interval, while a loss at 4 kHz would be expected to lengthen the interval.
(12) It is concluded the decrease in cellular volume associated with substitution of serosal gluconate for Cl results in a loss of highly specific Ba2+-sensitive K+ conductance channels from the basolateral plasma membrane.
(13) With prolonged ischemia, it is only transient and is followed by a gradual loss of the adenylyl cyclase activity.
(14) A murine keratinocyte cell line that is resistant to the growth-inhibitory effects of transforming growth factor beta 1 (TGF beta 1) was examined for differential gene expression patterns that may be related to the mechanism of the loss of TGF beta 1 responsiveness.
(15) Periodontal disease activity is defined clinically by progressive loss of probing attachment and radiographically by progressive loss of alveolar bone.
(16) But not only did it post a larger loss than expected, Amazon also projected 7% to 18% revenue growth over the busiest shopping period of the year, a far cry from the 20%-plus pace that had convinced investors to overlook its persistent lack of profit in the past.
(17) The findings confirm and quantitate the severe atrophy of the neostriatum, in addition to demonstrating a severe loss of cerebral cortex and subcortical white matter in HD.
(18) We could do with similar action to cut out botnets and spam, but there aren't any big-money lobbyists coming to Mandelson pleading loss of business through those.
(19) The triad of epigastric pain unrelieved by antacids, bilious vomiting, and weight loss, particularly after a gastric operation should make one suspect this syndrome.
(20) The temporary loss of a family member through deployment brings unique stresses to a family in three different stages: predeployment, survival, and reunion.
Ruin
Definition:
(n.) The act of falling or tumbling down; fall.
(n.) Such a change of anything as destroys it, or entirely defeats its object, or unfits it for use; destruction; overthrow; as, the ruin of a ship or an army; the ruin of a constitution or a government; the ruin of health or hopes.
(n.) That which is fallen down and become worthless from injury or decay; as, his mind is a ruin; especially, in the plural, the remains of a destroyed, dilapidated, or desolate house, fortress, city, or the like.
(n.) The state of being dcayed, or of having become ruined or worthless; as, to be in ruins; to go to ruin.
(n.) That which promotes injury, decay, or destruction.
(n.) To bring to ruin; to cause to fall to pieces and decay; to make to perish; to bring to destruction; to bring to poverty or bankruptcy; to impair seriously; to damage essentially; to overthrow.
(v. i.) To fall to ruins; to go to ruin; to become decayed or dilapidated; to perish.
Example Sentences:
(1) Because they generally have to be positioned on hills to get the maximum benefits of the wind, some complain that they ruin the landscape.
(2) Even regional allies disagree with American priorities about Isis, Biddle noted, which is why Turkey continues to bomb Kurds and Saudi Arabia and the UAE arm groups around the region , most notably in Syria but also in the ruins of Yemen .
(3) It trickled back to me somehow that, ‘Goddammit, Johnny Depp’s ruining the film!
(4) A procedure is described for the rapid determination of putrascine, spermine and spermidine in ruine and whole blood.
(5) Hitchcock's attempts to keep Hedren in a gilded cage arguably ruined her career.
(6) Conference, five years ago this motion would have ruined my life.
(7) But illegal action will only ruin any chance of dialogue with Tehran.
(8) The lid is fiddly to fit on to the cup, and smells so strongly of silicone it almost entirely ruins the taste of the coffee if you don’t remove it.
(9) In Niki Savva’s book The Road to Ruin: How Tony Abbott and Peta Credlin Destroyed Their Own Government, Credlin has even been compared to Wallis Simpson, a deeply weird analogy.
(10) "While the country is sunk in misery, families are ruined and children are growing up in poverty, this guy turns up and we pay €91m for him.
(11) Anuraj Sivarajah, online editor of the newspaper, said he was very clear who was to blame for the attacks and arson that has brought the newspaper near financial ruin.
(12) In 1995 8,000 people whose lives were ruined by the Montserrat volcano settled in Britain.
(13) They belong to the people who built Choquequirao, one of the most remote Inca settlements in the Andes, and were stashed here by the archaeologists who, over the past 20 years, have been slowly freeing the ruins from the cloud forest.
(14) Even the avuncular governor of the Irish central bank, Professor Patrick Honohan, was forced to admit that pumping up to €70bn of taxpayers' money into the ruined banks "doesn't score highly on fairness" when he announced the fifth bailout on Thursday.
(15) Three thousand cheers for Will Self ( Has English Heritage ruined Stonehenge?
(16) But Denton’s attempts to apply extreme openness to others could cost the ruin of his company.
(17) His torturers accused him of passing on to British officials information about previous beatings at the hands of state officials and other human rights abuses, to ruin diplomatic relations between the two countries, he said.
(18) As Google states, it is definitely in the company’s best interest to get its first smartglass customers to behave, as “breaking the rules or being rude will not get businesses excited about Glass and will ruin it for other Explorers”.
(19) The notion that Gleeson has lurched from one disaster to another, ruining everything from the Coen brothers' remake of True Grit to Richard Curtis's romcom About Time , seems a pretty unique interpretation of his burgeoning career as a versatile character actor.
(20) But there was scepticism over whether the more radical elements on either side would obey the ceasefire, and concern in Kiev and western capitals that the truce would effectively "freeze" the conflict and give Moscow de facto control over the disputed chunk of eastern Ukraine that has been ruined by war this summer.