(v. t.) Parted with unwillingly or unintentionally; not to be found; missing; as, a lost book or sheep.
(v. t.) Parted with; no longer held or possessed; as, a lost limb; lost honor.
(v. t.) Not employed or enjoyed; thrown away; employed ineffectually; wasted; squandered; as, a lost day; a lost opportunity or benefit.
(v. t.) Having wandered from, or unable to find, the way; bewildered; perplexed; as, a child lost in the woods; a stranger lost in London.
(v. t.) Ruined or destroyed, either physically or morally; past help or hope; as, a ship lost at sea; a woman lost to virtue; a lost soul.
(v. t.) Hardened beyond sensibility or recovery; alienated; insensible; as, lost to shame; lost to all sense of honor.
(v. t.) Not perceptible to the senses; no longer visible; as, an island lost in a fog; a person lost in a crowd.
(v. t.) Occupied with, or under the influence of, something, so as to be insensible of external things; as, to be lost in thought.
Example Sentences:
(1) On removal of selective pressure, the His+ phenotype was lost more readily than the Ura+ Trp+ markers, with a corresponding decrease in plasmid copy number.
(2) Significant amounts of 35S-labeled material were lost during the alkali treatment.
(3) Having been knocked out of the League Cup and Cup Winners' Cup before Christmas, they lost an FA Cup fourth-round replay at West Brom on 1 February.
(4) While they may always be encumbered by censorship in a way that HBO is not, the success of darker storylines, antiheroes and the occasional snow zombie will not be lost in an entertainment industry desperate to maintain its share of the audience.
(5) "David Cameron has lost control of what's happening in the NHS.
(6) As of November, 1988 after a median observation period of 34 months, 174 of the 256 patients (68%) were alive, 11 (4%) dead and 71 (28%) lost to follow-up.
(7) My thoughts are with all those who have lost loved ones or been injured in this barbaric attack.
(8) Significant side-effects occurred infrequently and only 2 children lost weight during the period of medication.
(9) Relative to the perceived severity of their asthma, both Maoris and Pacific Islanders lost more time from work or school and used hospital services more than European asthmatics using A & E. The increased use of A & E by Maori and Pacific Island asthmatics seemed not attributable to the intrinsic severity of their asthma and was better explained by ethnic, socioeconomic and sociocultural factors.
(10) Mendl's candy colours contrast sharply with the gothic garb of our hero's enemies and the greys of the prison uniforms – as well as scenes showing the hotel later, in the 1960s, its opulence lost beneath a drab communist refurb.
(11) What shouldn't get lost among the hits, home runs and the intentional and semi-intentional walks is that Ortiz finally seems comfortable with having a leadership role with his team.
(12) How big tobacco lost its final fight for hearts, lungs and minds Read more Shares in Imperial closed down 1% and British American Tobacco lost 0.75%, both underperforming the FTSE100’s 0.3% decline.
(13) From the treatment group 23 patients could be assessed: 2 had discontinued clean intermittent self-catheterization due to urethral hemorrhage, 2 died during the observation period and 1 was lost to followup.
(14) Size comparison of the newly discovered Msp I fragment with a restriction map of the apolipoprotein A-I gene revealed that most likely the cutting site at the 5'-end of the normally seen 673 bp fragment is lost giving rise to the observed 719 bp Msp I fragment.
(15) Another, discussing public attitudes towards the police, said: "I've lost count of [the number of] people who said: 'It's only cos you've got a uniform … if you didn't have the uniform on, I'd come and fuck you and this, that and the other … I hope your wife dies of cancer and your kids die of cancer.'"
(16) Co2+ partially restored the activities lost by chelation.
(17) The mean of the total daily energy intake was 104% of basal energy expenditure (BEE), and 70% of patients lost their weight.
(18) A lesser inhibitory effect (a decrease in the rate of precipitation) was observed when gallbladder bile was diluted but was lost after 10-fold dilution.
(19) Of the protein that did enter the gel, the higher MW species elicited banding patterns similar to patterns observed under reducing conditions, whereas lower MW IgE binding bands were lost.
(20) After cessation of exposures, HEVal was lost faster than predicted by the normal erythrocyte life span alone.
Ruination
Definition:
(n.) The act of ruining, or the state of being ruined.
Example Sentences:
(1) Thus references to an American financier Stan O'Neal who helped drive his bank to ruination in 2007 were "deleted".
(2) And one assumes the entire European Union financial establishment would invoke its own visions of Irish ruination if necessary.
(3) She isn't sure – though, like Freud, she defines her anxiety as a threat that is objectless, and located in the future – such as ruination or humiliation (unlike fear, which is a response to a specific and immediate threat to one's safety).
(4) It is shooting up the political agenda and, in the potential ruination of Britain's crops and vegetables, threatening the food security of a country that already imports 30% of its produce.
(5) The possibility is now that 3D printing technology can restore whole swaths of 20th-century ruination.
(6) Their photographs capture what has become a topos of post-war urban ruination: the exposed innards of buildings.
(7) Then there was Sir Fred Goodwin's ruination of the Royal Bank of Scotland, which would no longer exist had not the English taxpayer been available to provide the money to bail it out.
(8) Jack's editorial line: an end to the "unfair ruination of personalities" and "the sleaze and sensation that pass for journalism", plus a new, more upbeat message.
(9) In a Guardian interview for a recent series on the Scottish referendum, Carmichael predicted that a vote to leave the EU would mark the “ruination” of the UK.
(10) And this is a different kind of bad, far away from the life-destroying, shame-inducing, ruination-of-a-virgin stuff.
(11) The Mainichi Shimbun, often a progressive voice on other issues, devoted part of its front page yesterday to a fuming editorial warning of the potential ruination of Japan's finest universities by the evil weed.
(12) This suggests, and confirms the authors' clinical impression, that a combination of pharmacotherapy and behaviour therapy is the optimal treatment of choice for ritualistic patients who are almost always very ruinative, doubtful and highly anxious.
(13) He nevertheless presided over the ruination of the Royal Bank of Scotland.
(14) For those of us whose brackets had shot well past imperfection and into the realm of disastrous ruination, Dayton's upset was a joyful thing, a return to March Madness after a dreary afternoon of sensible predictability.
(15) And then: "My dear mother, 1,000 years ago, told me: 'Your tongue will be the ruination of you.'