(1) In a prospective study, the influence of the length of the time interval on spontaneous variability was investigated in 100 patients with CAD or IDC and untreated ventricular arrhythmia of Lown grade IV.
(2) According the degree of septal thickness (ST), patients were classed in 4 groups: (formula; see text) This study allows to conclude that mean and severe concentric LVH (ST greater than or equal to 12) detected by echo are associated with a greater PVC and a higher Lown's class ventricular ectopy.
(3) Three patients were withdrawn from the study at the end of the first period (1 after SR nicardipine and 2 after chlorthalidone) because of severe arrhythmias (Lown's class 4B) requiring antiarrhythmic therapy.
(4) A 79-year-old patient, who had received a pacemaker after suffering two posterior myocardial infarctions, was treated with 2 X 100 mg flecainide daily for 9 days for ventricular extrasystoles (Lown IV b).
(5) Ventricular arrhythmias were absent in 60% of the group, while among the 41 patients presenting these phenomena, as many as 32 presented simple forms, while only 5 were in Lown's class IV and 2 of these due to a single pairing, 1 a single triplet.
(6) A positive correlation was found between the extent of LV damage and the occurrence of complex arrhythmias expressed as the highest Lown class.
(7) The control-group revealed no late potentials although 4 patients had Lown IVa or more in Holter-ECG.
(8) The Lown and the Italian Modified Lown classifications were used.
(9) A new syndrome of ventricular pre-excitation syndrome is differentiated--of additional obscure retrograde conducting ventricular-atrial connection, different from the so far known syndrome of Wolff-Parkinson-White, Lown-Ganong-Levine and syndrome of Mahaim.
(10) Multivariate Cox's hazard function analysis on 18 variables, including age, type of infarction, Lown and Killip class, ejection fraction, and medications, showed that the presence of ST changes on Holter monitoring was a significant predictive variable for one-year mortality in the overall study population and particularly in the subgroup of 59 patients who could not undergo early exercise treadmill testing.
(11) Ventricular extra systoles were recorded in 31 patients (65.9%), 70.97% being from class III-V according to Lown.
(12) According to the long-term ECG recordings 22 patients were classified as Lown IV.
(13) Ventricular couplets or triplets (Lown grade IV) were found in less than 10% in patients in age from 15 to 17 years, 33% in patients from 18 to 20 years and showed no increase with age.
(14) In order to evaluate the effects of propafenone (an antiarrhythmic class 1 c agent) acutely administered intravenously on left ventricular function, 10 patients with acute myocardial infarction (AMI), affected by arrhythmias (greater than or equal to Lown class III), belonging to Killip class I and II, and with normal serum electrolyte levels, were studied 2-4 days after an acute episode.
(15) Thus the short PR wide QRS syndrome is not always a result of the Wolff-Parkinson-White syndrome but can also be seen in the Lown-Ganong-Levine syndrome coexisting with bundle-branch block.
(16) In 6 patients with normal resting electrocardiogram, AEM revealed: first degree A-V block (4 cases), class IVa Lown ventricular arrhythmias (3 cases) and episodes of atrial fibrillation (4 cases).
(17) The study population consisted of 27 pts; 22 (81%) were in Lown class 4A (18%) or 4B (63%).
(18) The Lown's type 3 ventricular beats had a 50% reduction.
(19) In order to clarify the role of age and hypertension in determining arrhythmias, we evaluated the average heart rate, and the number of supraventricular and ventricular premature beats and their severity (Lown grade) by 24-h Holter electrocardiography of 336 patients.
(20) The atrial depolarization pattern was studied in 22 patients with Wolff-Parkinson-White and Lown-Ganong-Levine syndrome.