(a.) Having a low esteem of one's own worth; humble; meek; free from pride.
(adv.) In a low manner; humbly; meekly; modestly.
(adv.) In a low condition; meanly.
Example Sentences:
(1) You will have to offer leadership and a sense of belonging to the civil service's lowly clerks and frontline staff in the Department for Work and Pensions, struggling not just with Iain Duncan Smith's fantasies of benefit rationalisation, but sharp contractors snapping at their heels.
(2) Chelsea, racism and the Premier League’s role | Letters Read more Mighty Manchester United had just been humbled by lowly Leicester City, battered 5-3.
(3) Pakistan repeated the trick in the 1990s, sending jihadists to stoke insurgency in Indian-held Kashmir and giving massive assistance to the Taliban, the once lowly mullahs’ movement that had seized control of Afghanistan in 1989.
(4) It has exalted the lowly and brought down the mighty from their seats.
(5) But one might have imagined Corbyn would have used the opportunity to send one of the really big power players of the new shadow cabinet – his transport spokeswoman Lilian Greenwood, say, or Nia Griffith, who has the Wales portfolio – rather than his lowly shadow chancellor.
(6) Historically, our masters have always imagined we lowly peasants will digest information more easily if it is written, for example, in a speech bubble coming out of the mouth of an imaginary squirrel pedestrian in yellow loon pants.
(8) One is a guy who has to try and take a lowly band of unknowns up against far better equipped adversaries, while having been tempted to join the other side, and the other one is … oh, hang on" – James Thomson.
(9) Within six years of beginning as a lowly prop assistant, he led the show to national syndication and had an Emmy to show for his efforts.
(10) One dev says: "My biggest bugbear at the moment (on my lowly 3GS) is the number of times app quit due to memory shortages, or because they've taken too long to load.
(11) An evening transformed by Adomah’s second-half liberation from the bench – (the winger created the excellent Stuani’s second) – ended with Boro looking the more convincing promotion candidates, but Brentford had played well enough to suggest their current lowly position is a false one.
(12) With such knowledge comes a predictable illusion of power, though this is all too regularly punctured by the indignity of being kicked out of shiny receptions and told to use an entrance more befitting of our lowly status – or of having my pronunciation of “Southwark Street” incorrectly corrected by a receptionist, who gives her colleague a sidelong smirk, commiserating over my supposed ignorance.
(13) In "Marching (As Seen from the Left File)", for instance, he describes the men from the perspective of one of them and in "Break of Day in the Trenches" he identifies with the lowly rat against the "haughty athletes".
(14) Basic literacy and numeracy skills are low, meaning that the children who drop out of school are on course for a life in lowly-paid jobs.
(15) Wolf Hall and Bring Up the Bodies trace the meteoric rise of Cromwell from the lowly son of a blacksmith to a ruthless political leader.
(16) In a telling Japanese ballet production of Bizet's Carmen a few years ago, Carmen was portrayed as a career woman who stole company secrets to get ahead and then framed her lowly security-guard lover José.
(17) Material released from the highly tumorigenic cells in response to increased cell density was also fucosylated (whereas shed material from lowly tumorigenic cells was not), suggesting a biological role for shed fucosylated antigens in tumor aggression.
(18) The G + C content of the A. nidulans genome is close to 50%, indicating little overall mutational bias, and so the codon usage of lowly expressed genes is as expected in the absence of selection pressure at silent sites.
(19) But my colleagues at the United States Holocaust Memorial Museum - where I spent the summer of 2000 as a lowly research assistant - questioned such reserve.
(20) There has been a decade-long legal battle by the Guardian involving rulings by 16 different judges, stretching from a lowly information tribunal to the supreme court, the highest in the land.
Profound
Definition:
(a.) Descending far below the surface; opening or reaching to a great depth; deep.
(a.) Intellectually deep; entering far into subjects; reaching to the bottom of a matter, or of a branch of learning; thorough; as, a profound investigation or treatise; a profound scholar; profound wisdom.
(a.) Characterized by intensity; deeply felt; pervading; overmastering; far-reaching; strongly impressed; as, a profound sleep.
(a.) Bending low, exhibiting or expressing deep humility; lowly; submissive; as, a profound bow.
(n.) The deep; the sea; the ocean.
(n.) An abyss.
(v. t.) To cause to sink deeply; to cause to dive or penetrate far down.
(v. i.) To dive deeply; to penetrate.
Example Sentences:
(1) With profound blockade, the slope of the edrophonium dose-response relationship was significantly flatter (P less than 0.05) than that of neostigmine.
(2) Cadavers have a multitude of possible uses--from the harvesting of organs, to medical education, to automotive safety testing--and yet their actual utilization arouses profound aversion no matter how altruistic and beneficial the motivation.
(3) Our positive experiences with IMACS discussed above should be even more profound and profitable for the larger medical institutions.
(4) This study compares the effects of 60 minutes of ischemic arrest with profound topical hypothermia (10 dogs) on myocardial (1) blood flow and distribution (microspheres), (2) metabolism (oxygen and lactate), (3) water content (wet to dry weights), (4) compliance (intraventricular balloon), and (5) performance (isovolumetric function curves) with 180 minutes of cardiopulmonary bypass with the heart in the beating empty state (seven dogs).
(5) About one out of three profoundly deaf children has an autosomal recessive form of inherited deafness.
(6) This continuing influence of Nazi medicine raises profound questions for the epistemology and morality of medicine.
(7) However six equivocal studies were observed in profoundly jaundiced patients with bilirubin levels above 400 mumol l-1 due to difficulties in differentiating extrahepatic obstruction from severe intrahepatic cholestasis.
(8) After a 2-day incubation with IL-4, expression of IL-2R p55 was markedly induced, but expression of IL2-R p70-75 was profoundly suppressed in a dose-dependent manner.
(9) "For those people who are able to use the laws, the change is profound."
(10) Most striking finding was his difficulty in identifying common objects and colours along with a profound alexia.
(11) This BOA technique was used to test the hearing of 82 profoundly involved handicapped children.
(12) These tools will allow us to manipulate the mammalian immune response in a variety of different ways that will have a profound impact both on our understanding of immunology and on medicine in the future.
(13) Based on the fact that all hibernators, at their regulated minimal body temperature, display a uniform turnover rate, related to body weight, the hypothesis is developed that cold tolerance of mammals is generally limited by a common specific minimal metabolic rate, which larger organisms, because of their lower basal metabolism, already attain in less profound hypothermia.
(14) Insulin-like growth factor II (IGF-II) is present at high levels in fetal and early neonatal rat plasma, and decreases profoundly following birth.
(15) The reduction in level of activity and adverse changes in body composition caused by SCI have profound metabolic consequences that may influence the progression and severity of coronary artery disease.
(16) The case of a 32-year-old man who suffered a blow to his left supraorbital region and eyebrow in an automatic closing door is reported to draw attention to the uncommon but trivial nature of this injury which may result in profound visual loss.
(17) In the paper life-threatening diseases which may be accompanied by profound unconsciousness are explained from the laboratory-chemical point of view.
(18) However pneumonia to PC points to a poor prognosis because they are always associated with a profound deficit or cellular immunity.
(19) Thus, it is possible that the loss of these dendritic cells may contribute to the profound immunological abnormalities seen in AIDS.
(20) They produce a more profound effect on clinical and biochemical aspects of rheumatoid arthritis than do the aspirin-like non steroidals.