(n.) The working parts of a machine, engine, or instrument; as, the machinery of a watch.
(n.) The supernatural means by which the action of a poetic or fictitious work is carried on and brought to a catastrophe; in an extended sense, the contrivances by which the crises and conclusion of a fictitious narrative, in prose or verse, are effected.
(n.) The means and appliances by which anything is kept in action or a desired result is obtained; a complex system of parts adapted to a purpose.
Example Sentences:
(1) It is argued that this process drove the evolution of present 5' and 3' splice sites from a subset of proto-splice sites and also drove the evolution of a more efficient splicing machinery.
(2) The data suggest that proinsulin, normally processed in secretory granules and released via the regulated pathway, may also be processed, albeit less efficiently, by the constitutive pathway conversion machinery.
(3) These observations suggest that pertubation of surface immunoglobulin molecules on CH31 immature B cells causes down-regulation of their antigen-processing machinery.
(4) We provide direct experimental evidence supporting the facts that these additional mechanistic components do exist and that the liver glutamate dehydrogenase reaction is indeed driven by just such machinery.
(5) These surplus chromophores become esterified and are temporarily taken up by the pigment epithelium to be re-entered into the visual cycle as fast as they can be processed by the regenerative machinery of the rod outer segments.
(6) Its diplomatic machinery is a little bit rusty," said Zhu Feng, of Peking University's centre for international and strategic studies.
(7) But, as extended survival at 43 degrees Celsius depends absolutely on the ability of cells to continually synthesize HSPs, it appears that a prior heat shock as well as the recovery from protein synthesis inhibition elicits a change in the protein synthetic machinery which allows the translation of HSP mRNAs at what would otherwise be a nonpermissive temperature for protein synthesis.
(8) Furthermore, the evidence that anti-CD3 antibodies increase the efficacy of the cytotoxic machinery might support the use of these molecules in designing new immunotherapeutic approaches against tumor targets.
(9) The mnn9 mutation also increases the transit time for invertase secretion, meaning that this mutation could affect the processing machinery in the Golgi apparatus.
(10) This technology allows the use of RNA virus replication machinery to express heterologous sequences.
(11) Geometrical comparison of this model with an experimentally determined structure for chicken DHFR suggests that chromosomal and type II R-plasmid specified enzymes may have independently evolved similar catalytic machinery for substrate reduction.
(12) To investigate whether TGF-beta also influences the glycosaminoglycan (GAG) chain-synthesizing machinery, we also characterized GAGs derived from proteoglycans synthesized by TGF-beta-treated cells.
(13) The effects of dantrolene on the sarcoplasmic reticulum and contractile machinery were examined in skinned skeletal muscles of guinea pigs.
(14) Secretion, however, depends on neither an N-terminal signal sequence nor on SecA, which is part of the normal cellular export machinery for periplasmic and outer membrane proteins.
(15) The localization of these key components of the pre-mRNA splicing machinery to speckled nuclear regions suggests that these regions may be involved in pre-mRNA splicing.
(16) In circumstances in which energy conversion rate and supplies of reducing power exceed the capacity of the biosynthetic machinery, energy-dependent H2 production presumably represents a regulatory device that facilitates "energy-idling."
(17) Overexpression of these genes, which probably encode lipoproteins, could have deleterious effects on E. coli hosts, possibly as a result of impairing the protein export machinery.
(18) Major intra-abdominal arteriovenous fistulas usually present with a machinery bruit over a pulsatile mass, but may present more subtly with pain and otherwise unexplained hematuria.
(19) Sales of tractors and other farm machinery are down by 70%, said Dave Dorsett of Reynolds farm equipment in Martinville.
(20) By using a temperature-sensitive allele, we have found that that norpA mutation has little or no effect on either the rhodopsin-metarhodopsin transition or the machinery of quantum bump production.
Predecessor
Definition:
(n.) One who precedes; one who has preceded another in any state, position, office, etc.; one whom another follows or comes after, in any office or position.
Example Sentences:
(1) It became fully operational in 1975, replacing its predecessor the rubber bullet.
(2) Gerhard Schröder , Merkel’s immediate predecessor, had pushed through parliament a radical reform agenda to get the country’s spluttering economy back on track.
(3) Her predecessor, Bingu wa Mutharika, had fallen out with international donors, but Banda managed to rebuild relationships.
(4) The problem is that too many people in this place just get advised by people who are just like them, so there’s groupthink, and they have no sense of what it’s like out there.” Is he talking about his predecessor?
(5) He looks set to become a stronger leader than his cautious predecessor, Hu Jintao, but he is no radical reformer, experts say.
(6) 9.59am GMT Summary We’ll leave you with a summary of what transpired here throughout the day: • Julia Gillard announced a contest for her position as prime minister following calls by Simon Crean, a senior minister in her government, for her to be replaced by her predecessor, Kevin Rudd • Shortly before the ballot was to take place Kevin Rudd announced he would not stand for the Labor Party leadership , re-iterating his promise to the Australian people that he would not challenge Julia Gillard • When it came time for the ballot, Gillard was the only person who stood for the leadership and she and her deputy Wayne Swan were elected unopposed .
(7) Banda, 64, began her term as a darling of the west, inheriting the presidency after the unexpected death of her predecessor, Bingu wa Mutharika, in 2012.
(8) Sources have confirmed that there are significant tensions within the party over the Unite trade union’s active support for Corbyn, following personalised attacks by its general secretary Len McCluskey on Jim Murphy, Dugdale’s predecessor as Scottish leader.
(9) But we won’t take risks with him.” In March 2013 Roberto Mancini, Pellegrini’s predecessor at City, criticised Wilmots for fielding Kompany against Macedonia after a 60-day absence due to a calf injury.
(10) But it is the presence of Webb on the list that is potentially most troubling for Blatter, who has been at Fifa for 40 years since moving from watchmaker Longines to become the protege of his now disgraced predecessor João Havelange.
(11) May is thought to have been keen to examine more closely the role of Chinese companies in the project amid concerns about the impact on national security and despite her predecessor David Cameron’s strong support for Hinkley .
(12) The room never existed in the Palais Garnier, but belongs to its predecessor the Opera Choiseul which had burned to the ground some years earlier.
(13) There’s no doubt that Battlefield: Hardline will be much more approachable for those who haven’t bought into its predecessors.
(14) While his more eminent predecessors, Gerald Durrell and John Aspinall, established that displaying wild creatures may occasionally be compatible with respect for them, zoos around the world have also sanitised – with extravagant claims about conservation, breeding programmes and species reintroduction – the essentially unchanged business of showing caged animals for cash.
(15) Rahm may still win but it’s going to be much more of a free-for-all at that point.” Larry Bennett, a political scientist at DePaul University in Chicago, said many of Chicago’s problems, such as systemic population loss and crime, went back decades and were never solved by his predecessor, Richard M Daley, who was mayor for six terms.
(16) In general, several modifications can result in a particular series of composite molecules that possess a biologic potency greater than each of its predecessors; this correlation of structure with activity was more consistent in the [D-Ala6]-series than in the [D-Trp6]-series.
(17) But Shukrallah says groups like Dostour are weak not through laziness but because they were not allowed to develop under Mubarak and his predecessors.
(18) Obama was still in a nappy during the 1962 Cuban missile crisis, when his predecessor John F Kennedy faced down the Soviet Union’s efforts to site atomic weapons on the island that is just a few dozen miles from Florida.
(19) The conciliatory language marked a radical change from the presidency of his predecessor, Mahmoud Ahmadinejad, and a break from tradition dating to the 1979 revolution of referring to the US as the "Great Satan".
(20) Labeled protein predecessors were selected as indicators of retinal-cell element viability.