(1) In addition, there is immunocytochemical evidence for abnormal accumulation of MAG in perikarya of oligodendroglial-like cells, suggesting the possibility of a transport block for myelin proteins in the shiverer mutant.
(2) In the studies on genomic DNA, genes with multiple transcription initiation sites were found in brain, such as CCK, CNP and MAG, in addition to NSE which was a housekeeping gene, and this may contribute to the high sequence complexity of brain RNA.
(3) Double staining with anti-MAG and anti-P0 antibodies showed that there was essentially no P0 immunoreactivity in the same cells.
(4) In a multicentre study, 146 peptic ulcer patients who had recently healed with H2 antagonists (38 gastric, 108 duodenal ulcers) received randomly for a year one of the following mucosal protecting antiulcer drugs: aceglutamide aluminium salt (AAL), zinc acexamate (ZAC) and magaldrate (MAG).
(5) MAG-enriched MVBs were not found in oligodendrocytes from adult animals or in myelinating Schwann cells.
(6) Antibodies to MAg inhibited the outgrowth of neurites on Schwann cells to the same extent as treatment with the two cytokines.
(7) These are all sites associated with the presence of MAG.
(8) Mags, from South Thanet, expressed her exasperation: “They’re all out for themselves.
(9) Strikingly, there was no greater homology between the H chain V regions of the anti-MAG IgM.
(10) Partial aminoterminal sequence of heavy and light chains showed that anti-MAG IgM use either lambda chains (one IgM) or kappa light chains (six IgM) of different variability subgroups (V kappa IV in three instances, V kappa I in two, and V kappa II in one), whereas heavy chains belong to the VHIII (six IgM) or to the VHII (1 IgM) subgroup.
(11) The remaining human natural killer (NK) cell activity examined by using K-562 cells at 20:1 as effector:target ratio after treatment of anti-MAG monoclonal mouse or anti-Leu-7 (HNK-1) antibody and complement revealed 13.4% and 15.1%, respectively (untreated NK activity was 40.8%).
(12) The results demonstrate that the anti-melanoma antibodies fall into a class of monoclonal antibodies (including HNK-1, human IgM paraproteins associated with neuropathy, anti-human MAG antibodies, and L2 antibodies) that are characterized by reactivity against related carbohydrate determinants shared by human MAG, N-CAM, and several protein and lipid glycoconjugates of the PNS.
(13) These results suggest that the decreasing high-molecular-weight MAG is important for compaction of myelin in the early stage of myelination.
(14) In fact, the MAG-nonreactive patients were a heterogeneous group, both electrodiagnostically and clinically.
(15) We used neuron-specific enolase (NSE), S-100 beta (S-100), and myelin-associated glycoprotein (MAG) for molecular markers of neuron, astrocyte, and oligodendrocyte, respectively.
(16) The soluble form of MAG which contains most, if not all, of the extracellular domain of the molecule and binds to collagen, did not interfere with the binding of MAG-liposomes to neurons.
(17) Thus, the carbohydrate epitope(s) in MAG which is shared with nerve acidic glycolipids appears to be highly immunogenic in mice and rabbits.
(18) The results suggest that IgM paraproteins, HNK-1 and some mouse monoclonal antibodies react with carbohydrate determinants shared by MAG and several lower molecular weight glycoproteins present only in human, bovine, cat and chicken PNS.
(19) The intensity of the staining with MAG antiserum in the white matter was clearly decreased in TM-treated cerebellum compared with the control.
(20) The number of 7S and 19S Ig-secreting cells (ISC) found in the spleen and the number of ISC generated after in vitro stimulation of the cells with MAG antigens were evaluated by using the hemolytic plaque assay.
Sagged
Definition:
(imp. & p. p.) of Sag
Example Sentences:
(1) When the posterior capsule was sectioned, no significant changes were noted in the severity of the sag or the rotation.
(2) Axonal regeneration with the ANG was equal to SAGs as measured by axonal diameters, physiological, and functional methods, although the SAG demonstrated statistically higher axonal counts.
(3) Yards away from a genuine station, he used a huge funnel to fill up a car sagging under the weight of its occupants and market produce.
(4) Guanacline, but not guanethidine or SAG, produced fluorescent lipopigment in all species examined.
(5) For cross-linked alpha alpha, however, the curve sags at temperatures somewhat below the region of principal cooperative loss of helix, the latter occurring at higher temperature but with the same steepness as in the non-cross-linked case.
(6) Myosin ATPase staining showed that about 80% of the LGM consists of type II A fibres, whilst the remainder are type II B. Physiological determination of the contractile properties of motor units indicated two classes of units: those that were relatively fatigue resistant and did not show a sag property (like fast-twitch, fatigue-resistant fibres or FR) and those that were relatively fatigable and did show a sag property (like fast-twitch, fatigable fibres or FF).
(7) The time-dependent sag elicited by hyperpolarization was reduced when Na+ or K+ was removed from the normal bath solution but was abolished with the removal of both Na+ and K+.
(8) In his bid to revitalise Spain's sagging monarchy, Felipe VI must be willing to show that he will handle things differently to his father, said Urreiztieta.
(9) By lacking possibilities of the comparison of equivalent (produced under the same preparation and storage conditions) concentrates of erythrocytes the higher transfusion efficiency of the SAG-S concentrates of erythrocytes to be expected could not be verified.
(10) This domed white building is now a magnet for national expectations, and many wonder whether it will sag under the weight of so much anticipation.
(11) Superantigens (SAg) interact with T lymphocytes bearing particular V beta sequences as part of their T cell receptor (TcR).
(12) Both produce substantial labeling of PC but [14C]SMG gives rise to the highest proportion of TG and the lowest of PA and PI, whereas [14C]SAG yields the opposite pattern.
(13) There is nowhere to go except further into an area of the city 750 metres wide by 500 metres deep that runs along the coast from the television station – with its pair of wrecked and punctured dishes – to the edge of District Two, overlooked by the pavilion and its sagging roof.
(14) As the temperature of the tarts increases a race will start between the sag of melting fat and the drying of the structure-forming gluten network.
(15) Several species were treated chronically with varying doses of guanethidine, guanacline or SAG; the superior cervical ganglia were examined light microscopically for neuronal destruction and for osmiophilic fluorescent lipopigment accumulation.
(16) An important exception concerned SE to which an equal antibody response is produced in high and low lines of sAg selection.
(17) Cheerful and eager to be helpful, he arrives to collect me the following morning, dressed in sagging brown corduroy jacket, faded blue T-shirt, blue silk cravat and socks beneath his Velcro-strapped sandals.
(18) A statistically significant improvement was observed, on the SAG score obtained during the follow-up, in patients (n = 16) who were not admitted to hospital in the 12 month period following discharge.
(19) Jannetta has summarized this concept as follows: "As we age, our arteries elongate and our brains 'sag'.
(20) The observation that ingrowth of SAG neurites to presumptive sensory areas of the inner ear preceded cytodifferentiation of those receptor cells suggested a causal relationship.