What's the difference between major and significant?

Major


Definition:

  • (a.) Greater in number, quantity, or extent; as, the major part of the assembly; the major part of the revenue; the major part of the territory.
  • (a.) Of greater dignity; more important.
  • (a.) Of full legal age.
  • (a.) Greater by a semitone, either in interval or in difference of pitch from another tone.
  • (a.) An officer next in rank above a captain and next below a lieutenant colonel; the lowest field officer.
  • (a.) A person of full age.
  • (a.) That premise which contains the major term. It its the first proposition of a regular syllogism; as: No unholy person is qualified for happiness in heaven [the major]. Every man in his natural state is unholy [minor]. Therefore, no man in his natural state is qualified for happiness in heaven [conclusion or inference].
  • (a.) A mayor.

Example Sentences:

  • (1) In contrast, resting cells of strain CHA750 produced five times less IAA in a buffer (pH 6.0) containing 1 mM-L-tryptophan than did resting cells of the wild-type, illustrating the major contribution of TSO to IAA synthesis under these conditions.
  • (2) With NaCl as the major constituent of the bathing solution (potassium-free pipette and external solutions) the reversal potential (Er) of the noradrenaline-evoked current was about 0 mV.
  • (3) After 4 to 6 hours of recirculation, accumulation of vasoactive amine, 5-hydroxytryptamine, its major metabolite, 5-hydroxyindole acetic acid, and its precursor amino acid, tryptophan were detected.
  • (4) The major treatable risk factors in thromboembolic stroke are hypertension and transient ischemic attacks (TIA).
  • (5) The promoters of the adenovirus 2 major late gene, the mouse beta-globin gene, the mouse immunoglobulin VH gene and the LTR of the human T-lymphotropic retrovirus type I were tested for their transcription activities in cell-free extracts of four cell lines; HeLa, CESS (Epstein-Barr virus-transformed human B cell line), MT-1 (HTLV-I-infected human T cell line without viral protein synthesis), and MT-2 (HTLV-I-infected human T cell line producing viral proteins).
  • (6) The data suggest that major differences may exist between ruminants and non-ruminants in the response of liver metabolism both to lactation per se and to the effects of growth hormone and insulin.
  • (7) Then a handful of organisers took a major bet on the power of people – calling for the largest climate change mobilisation in history to kick-start political momentum.
  • (8) This finding is of major importance for persons treated with diltiazem who engage in sport.
  • (9) Blatter requires a two-thirds majority of the 209 voters to triumph in the opening round, with a simple majority required if it goes to a second round.
  • (10) Further analysis with two other synthetic peptides (212Cys to 222Glu and Cys X 221Ile to 236Glu) indicated that the dodecapeptide Ile-Glu-Phe-Gln-Lys-Asn-Asn-Arg-Leu-Leu-Glu mimicked either the whole or a major part of the neutralization epitope.
  • (11) Inadequate treatment, caused by a lack of drugs and poorly trained medical attendants, is also a major problem.
  • (12) Even so, amputation of fifteen extremities and four other major excisions were required in twelve patients.
  • (13) In this study, standby and prophylactic patients had comparable success and major complication rates, but procedural morbidity was more frequent in prophylactic patients.
  • (14) These major departmental transformations are being run in isolation from each other.
  • (15) Epidemiological studies on low risks involve a number of major methodological difficulties.
  • (16) Given Australia’s number one position as the worst carbon emitter per capita among major western nations it seems hardly surprising that islanders from Fiji, Samoa, Vanuatu and other small island developing states have been turning to Australia with growing exasperation demanding the country demonstrate an appropriate response and responsibility.
  • (17) The time-course and dose-response for this modification of pp60c-src paralleled PDGF-induced increases in phosphorylation of pp36, a major cellular substrate for several tyrosine-specific protein kinases.
  • (18) The degree of increase in Meth responsiveness elicited by the initial provocation is a major factor in determining the airway response to a subsequent HS challenge.
  • (19) On the other hand, the majority of gynecologic patients with pelvic infections are young and healthy.
  • (20) Confidence is the major prerequisite for a doctor to be able to help his seriously ill patient.

Significant


Definition:

  • (a.) Fitted or designed to signify or make known somethingl having a meaning; standing as a sign or token; expressive or suggestive; as, a significant word or sound; a significant look.
  • (a.) Deserving to be considered; important; momentous; as, a significant event.
  • (n.) That which has significance; a sign; a token; a symbol.

Example Sentences:

  • (1) Once treatment began, no significant changes occurred in Group 1, but both PRA and A2 rose significantly in Groups 2 and 3.
  • (2) However, patients with GGBHS were significantly older (P less than .05).
  • (3) In each sheep there was a significant negative correlation between the glucose and corticosteroid concentrations in both maternal and fetal plasma, and there were positive correlations between the maternal and fetal plasma concentrations of glucose, and between the glucose and fructose concentrations of fetal plasma.
  • (4) Such a decrease significantly biased survival (p = 0.001).
  • (5) This may have significant consequences for people’s health.” However, Prof Peter Weissberg, medical director of the British Heart Foundation, which funded the work, said medical journals could no longer be relied on to be unbiased.
  • (6) It is supposed that delta-sleep peptide along with other oligopeptides is one of the factors determining individual animal resistance to emotional stress, which is supported by significant delta-sleep peptide increase in hypothalamus in stable rats.
  • (7) However, when first trimester specimens were analyzed, the direct-product measurements were significantly larger than the corresponding 3H2O assay results.
  • (8) The Na+ ionophore, gramicidin, had a small but significant inhibitory effect on Na(+)-dependent KG uptake, demonstrating that KG uptake was not the result of an intravesicular positive Na+ diffusion potential.
  • (9) Propranolol resulted in a significantly lower mean hourly, mean 24 h and minimum heart rate.
  • (10) In some other countries the patient-to-nurse ratio was significantly smaller.
  • (11) The findings indicate that there is still a significant incongruence between the value structure of most family practice units and that of their institutions but that many family practice units are beginning to achieve parity of promotion and tenure with other departments in their institutions.
  • (12) The significance of minor increases in the serum creatinine level must be recognized, so that modifications of drug therapy can be made and correction of possibly life-threatening electrolyte imbalances can be undertaken.
  • (13) The process of sequence rearrangement appears to be a significant part of the evolution of the genome and may have a much greater effect on the evolution of the phenotype than sequence alteration by base substitution.
  • (14) The low affinity of several N1-alkylpyrroleethylamines suggests that the benzene portion of the alpha-methyltryptamines is necessary for significant affinity.
  • (15) During control, no significant difference between systolic fluctuation (delta Pa) and pleural swings (delta Ppl) was found.
  • (16) Urinary ANF immunoreactivity was significantly enhanced by candoxatril in both groups (P less than 0.05 and P less than 0.01 in groups 1 and 2, respectively), with a more pronounced effect evident at the higher dose (P less than 0.01).
  • (17) Both lymph flow from cannulated pancreatico-duodenal lymphatics and intralymphatic pressure in the non-transected ones increased significantly.
  • (18) We conclude that the priming effect is not a clinically significant phenomenon during natural pollen exposure in allergic rhinitis patients.
  • (19) This study examined the [3H]5-HT-releasing properties of 3,4-methylenedioxymethamphetamine (MDMA) and related agents, all of which cause significant release of [3H]5-HT from rat brain synaptosomes.
  • (20) However, the degree of sedation caused by diphenhydramine was significantly greater than that caused by cimetidine (P = .0001).