What's the difference between malacosteon and osteomalacia?
Malacosteon
Definition:
(n.) A peculiar disease of the bones, in consequence of which they become softened and capable of being bent without breaking.
Example Sentences:
Osteomalacia
Definition:
(n.) A disease of the bones, in which they lose their earthy material, and become soft, flexible, and distorted. Also called malacia.
Example Sentences:
(1) When in addition the serum P is low (which was a feature of male patients), the danger exists for osteomalacia to develop.
(2) Osteomalacia is characterized by large osteoid seams and a preserved volume of bone trabeculae.
(3) Chronic ingestion of certain drugs can lead to osteomalacia and hypocalcemia by potentiating the metabolism of vitamin D to inactive compounds.
(4) Whereas markedly high values of 1, 25-(OH)2D in plasma were found in some cases of primary hyperparathyroidism with prominent bone resorption, relatively low values were seen in some patients with chronic renal failure, senile osteoporosis, osteomalacia and hypercalcemia due to bone metastasis.
(5) The growth plates did not increase in width despite the presence of osteomalacia and histologic evidence of extensive deposition of aluminum in bone.
(6) A follow-up biopsy examined after 12 months of therapy showed almost complete healing of osteomalacia and normal mineralization.
(7) The fractures, which appeared on roentgenograms as transverse radiolucent zones with variable callus formation, healed slowly or not at all despite treatment with calcium and vitamin D. They resembled pseudofractures (Looser's transformation zones) radiologically, but the biochemical and histologic findings were those of idiopathic osteoporosis rather than osteomalacia.
(8) A third had intestinal malabsorption, 20 had features of osteomalacia, and 87 were iron deficient.
(9) Treatment will depend on the predominant bone lesions: secondary hyperparathyroidism or osteomalacia.
(10) The various abnormalities occurred alone or in combination with one another and, to a large extent, independently of serum biochemistry.Radiological examination failed to diagnose the histological abnormality in 12 of 13 patients with osteomalacia and in 10 of 25 patients with osteitis fibrosa.
(11) The serum bio-PTH assay was useful in identifying patients with osteomalacia, low turnover bone disease, or aluminum accumulation.
(12) Thus, fractures in patients with renal failure and accumulation of aluminum may result not only from osteomalacia but also from osteopenia.
(13) Osteomalacia due to impaired liver hydroxylation of vitamin D can hardly explain the increased fracture rate and the decreased bone mass, which have been described in alcoholics.
(14) Bone biopsies (n = 3) showed a normal mineralization and the disappearance of the osteomalacia.
(15) The secondary hyperparathyroidism followed by uremic renal osteodystrophy did not result in an osteomalacia.
(16) It was shown that the serum 25-hydroxycholecalciferol level and the skeletal radiograph were the most valuable in the early detection of osteomalacia.
(17) Elevated levels persisted for six to twelve weeks after fracture, the major influence upon the level at this time being the maximum value achieved rather than the presence of osteomalacia.
(18) Pre-treatment biopsies showed signs of osteomalacia and hyperparathyroidism.
(19) We conclude that in patients with osteomalacia, a condition which is characterized by an increased osteoid accumulation due to a decreased mineralization rate, the increased level of serum osteocalcin reflects the increased osteoid synthesis but not the mineralization defect.
(20) In addition, they point out the subtle ways in which less commonly encountered metabolic bone diseases, such as osteomalacia, hyperparathyroidism, and Paget's disease, might come to the attention of the orthopedist.