(n.) Air infected with some noxious substance capable of engendering disease; esp., an unhealthy exhalation from certain soils, as marshy or wet lands, producing fevers; miasma.
(n.) A morbid condition produced by exhalations from decaying vegetable matter in contact with moisture, giving rise to fever and ague and many other symptoms characterized by their tendency to recur at definite and usually uniform intervals.
Example Sentences:
(1) The rise of malaria despite of control measures involves several factors: the house spraying is no more accepted by a large percentage of house holders and the alternative larviciding has only a limited efficacy; the houses of American Indians have no walls to be sprayed; there is a continuous introduction of parasites by migrants.
(2) Eighty-two per cent of patients with falciparum malaria had recently returned from Africa whereas 82% with vivax malaria had visited Asia.
(3) 236 patients with malaria were examined and treated.
(4) But both for malaria and Aids we’re seeing the tools that will let us do 95-100% reduction.
(5) In assessing damaged nets and curtains it must be recognised that anything less than the best vector control may have no appreciable impact on holoendemic malaria.
(6) Since then the intensive development of anti-malaria campaigns in urban areas over about ten years led temporarily to a considerable decrease in the level of endemicity, while in rural areas it remained unchanged.
(7) On land, the pits' stagnant pools of water become breeding grounds for dengue fever and malaria.
(8) immunoglobulin, purified from the plasma of local semi-immune blood donors, as an adjunct to standard treatment for cerebral malaria in Malawian children.
(9) Treatment with chloroquine and primaquine, together with packed red cell transfusions, was successful in eliminating both the malaria parasites and the leukaemoid blood picture.
(10) These C+ and R+ adherence properties of PE appear to mediate much of the pathogenesis of severe malaria infections, in part by blocking blood flow in microvessels.
(11) There was less of an increase following a blood meal infected with the rodent malaria parasite, Plasmodium berghei.
(12) Clindamycin, a semi-synthetic antibiotic of the lincomycin family, at a dose of 450 mg eight-hourly for three days in adults cured five out of 10 patients moderately ill with chloroquine-resistant falciparum malaria.
(13) This test by virtue of its high sensitivity and the facilities in processing a large number of specimens, can prove to be useful in endemic areas for the recognition of asymptomatic malaria and screening of blood donors.
(14) A small clinic consisting of 1 room decorated with pamphlets against AIDS, malaria, and other diseases was managed by the chief primary health care (PHC) assistant named Joseph.
(15) Prospects for involvement in malaria control are numerous, however there is need to enhance the existing BHW Program.
(16) This latter event might be one of the factors which results in a correlation of Burkitt's lymphoma with malaria endemic regions.
(17) Hemoglobin S (Hb S) was significantly more prevalent in adults resistant to malaria.
(18) The proportion of persons with P. malariae in this sample population, as determined by slide examination, appears to be the greatest ever reported for any area before the introduction of control measures.
(19) Other causes are malaria (21), undernutrition (12), meningitidis (10), diarrhea (9), pneumopathy (7), endogenous and obstetrical causes (24).
(20) An indirect fluorescent antibody test for glutaraldehyde-fixed, ring-infected erythrocyte surface antigen was performed on admission sera from 45 patients with complicated cerebral Plasmodium falciparum malaria, 33 with uncomplicated cerebral malaria, 91 non-cerebral malaria patients, and 53 blood donors from a non-malarious area.
Quinine
Definition:
(n.) An alkaloid extracted from the bark of several species of cinchona (esp. Cinchona Calisaya) as a bitter white crystalline substance, C20H24N2O2. Hence, by extension (Med.), any of the salts of this alkaloid, as the acetate, chloride, sulphate, etc., employed as a febrifuge or antiperiodic. Called also quinia, quinina, etc.
Example Sentences:
(1) The influence of the hexylsalicylic acid (2) on the pharmacokinetic of the quinine (1), was studied using rabbits.
(2) Concomitant with the inhibition of K+ and Na+ transport, quinine stimulates ATP hydrolysis by 57%.
(3) those that had entered the G1 phase) expressed an increased amount of Fc gamma RII and (b) blocking the entry of activated cells into the S phase (with the ion channel blocker quinine) did not affect the Fc gamma RII induction by LPS.
(4) It was found that DI rats responded less than LE rats on the progressive-ratio schedule and that DI rats suppressed drinking as much as LE rats at each concentration of quinine used on the drinking-suppression test.
(5) Microsomal metabolites were also isolated from quinine and quinidine incubations with rabbit or guinea pig liver fractions.
(6) A nearly complete blockade of channel current was observed at 100 nM quinine and above.
(7) Treatment may be delayed because the therapy recommended for severe or complicated disease, intravenous quinine dihydrochloride, is available only from the Centers for Disease Control.
(8) Cell proliferation was equally sensitive to quinine regardless of mitogen.
(9) The responses to quinine and mefloquine or halofantrine showed no correlation with each other.
(10) The CGRP-IR levels in the rostral (gustatory) part of the insular cortex were increased significantly by strongly aversive taste stimuli such as quinine hydrochloride and conditioned taste stimuli (NaCl and sucrose) which animals had been taught to avoid.
(11) Quinidine, the stereoisomer of quinine, had no effect on either cells from the patient or normal cells.
(12) Despite the presence in the region of an important resistance of Plasmodium falciparum to chloroquine (80% specimens), one can conclude to a satisfying susceptibility of this parasite to quinine, provided posology and divided doses are respected.
(13) The clinical application of the method for routine drug monitoring and for estimating the pharmacokinetics of quinine and quinidine in man are discussed.
(14) The resistance of Plasmodium falciparum, the cause of tertian malaria, to synthetic antimalarials, together with the resistance of the vector mosquitoes to insecticides, has resulted in a resurgence in the use of quinine and a search for new antimalarial agents.
(15) all infections were sensitive to quinine plus tetracycline.
(16) Quinine applied on the intracellular side of the membrane in micromolar concentrations chopped the unitary K+ currents into bursts of brief openings.
(17) This was shown by a dye exclusion test and by mitogen stimulation after exposure and removal of quinine from the medium.
(18) These are insensitive to quinine, suggesting that they are not caused by an intracellular Ca accumulation.
(19) The spread of chloroquine-resistant malaria has led to a resurgence of quinine in clinical use.
(20) Whether it was Sénac or Wenckebach who first observed that quinine could change an irregular heart rhythm (atrial fibrillation) into a regular one (sinus rhythm), we are not far from their empiricism.