(n.) The state or quality of being malignant; extreme malevolence; bitter enmity; malice; as, malignancy of heart.
(n.) Unfavorableness; evil nature.
(n.) Virulence; tendency to a fatal issue; as, the malignancy of an ulcer or of a fever.
(n.) The state of being a malignant.
Example Sentences:
(1) In contrast to previous reports, these tumours were more malignant than osteosarcomas and showed a five-year survival rate of only 4-2 per cent.
(2) Oral administration in domestic cats causes malignant hepatomas and tumors of the esophagus and kidney.
(3) In view of reports of the reduction of telomeric repeats in human malignant tumors, we measured the lengths of telomeric repeats in 55 primary neuroblastomas.
(4) The frequency of gastric malignancies in the families of the women with gastric polyps was higher than in the controls and in men, 6.2, 3.1 and 2.4 percent, respectively (p less than 0.05, and p less than 0.025).
(5) In 60 rhesus monkeys with experimental renovascular malignant arterial hypertension (25 one-kidney and 35 two-kidney model animals), we studied the so-called 'hard exudates' or white retinal deposits in detail (by ophthalmoscopy, and stereoscopic color fundus photography and fluorescein fundus angiography, on long-term follow-up).
(6) The only localized tumors known to produce elevation of CEA above the levels observed in non malignant diseases are carcinomas of the large bowel and the pancreas.
(7) Normal cultured human epidermal melanocytes and melanoma cells derived from three different malignant melanomas were examined for synthesis of extracellular matrix components before and after treatment for one day with interferon-gamma, tumor necrosis factor-alpha, or both.
(8) The presence of these markers has facilitated the identification and characterization of the mononuclear cells in a number of animal and human lymphoid malignancies.
(9) Benign and malignant epithelial and soft tissue tumors of the skin were usually negatively stained with MoAb HMSA-2.
(10) HCT were classified by light microscopy as benign (n = 22), intermediate (n = 30), and malignant (n = 13).
(11) This case is unusual in that it demonstrated no malignant epithelium beyond that of a borderline tumor, but met the criteria of malignancy because of its invasiveness and metastasis.
(12) As novel antibody therapeutics are developed for different malignancies and require evaluation with cells previously uncharacterized as antibody-dependent cell-mediated cytotoxicity (ADCC) targets, efficient description of key parameters of the assay system expedites the preclinical assessment.
(13) The fragile site at 10q25 was expressed in larger proportions of malignant than normal cells.
(14) In the control group it was 18% and in other malignancies 20%.
(15) Total lactate dehydrogenase (LDH; EC 1.1.1.27) activity and the percentage distribution of LDH isoenzymes were determined in 127 patients with malignant diseases.
(16) In our opinion, a carcinologically "malignant" metastatic myxoma remains a questionable pathological entity.
(17) Hexokinase, phoshofructokinase, and aldolase appear to be rate-limiting in normal cervix epithelium; however, since the increase in activity of the first two in cancers was least of all the glycolytic enzymes, redundant enzyme synthesis probably occurs in the malignant cell for the enzymes catalysing reversible reactions.
(18) The flow cytometric measured DNA content (i.e., DNA index), S-fractions, and histopathologic malignancy grades were studied for ninety uterine cervical squamous cell carcinomas using tissue biopsies taken prior to radiotherapy.
(19) Changes in the plasma lipid composition are observed in patients and animals with malignancy and certain other diseases that are consistent with peroxidation of plasma lipoprotein lipids.
(20) It was difficult to assess the diagnosis of malignant mesothelioma on isolated differentiated mesothelial cells in pleural fluids or biopsies.
Neoplasm
Definition:
(n.) A new formation or tissue, the product of morbid action.
Example Sentences:
(1) The types, frequency, and clinical features of neoplasms encountered in the perinatal period are markedly different from those observed in older children and adolescents.
(2) We identified four distinct clinical patterns in the 244 patients with true positive MAI infections: (a) pulmonary nodules ("tuberculomas") indistinguishable from pulmonary neoplasms (78 patients); (b) chronic bronchitis or bronchiectasis with sputum repeatedly positive for MAI or granulomas on biopsy (58 patients, virtually all older white women); (c) cavitary lung disease and scattered pulmonary nodules mimicking M. tuberculosis infection (12 patients); (d) diffuse pulmonary infiltrations in immunocompromised hosts, primarily patients with AIDS (96 patients).
(3) Of 3,837 canine neoplasms from case records at Kansas State University, only 4 were of carotid body tumors.
(4) Utilization of the immunoglobulin system is based upon the supposition that in lymphoid neoplasms with clonal origin either all or none of the tumor cells should have surface-associated IgM and kappa-reactivities.
(5) Chromosome abnormalities linked to several neoplasms have been previously associated with this region on human chromosome 14.
(6) Staplers were used and therefore the choice between resection or amputation was determined by the degree of loco-regional infiltration of the neoplasm.
(7) Frequent measurement of serum cation and appropriate replacement are recommended when high dose Cisplatin containing regimen is used in chemotherapy of neoplasms.
(8) However, the typically deep invasion of the former tumors and their histologic features indicate that they are highly aggressive neoplasms.
(9) That most of the neoplasms found were adenomas and not invasive cancer may be due to the relative youth of most of those screened.
(10) Ultrastructural differences between normal neoplasmic cells observed in this work may be the cause of the behaviour of neoplastic cells in tissue culture.
(11) We have demonstrated by electron microscopic and immunohistochemical means that these neoplasms can exhibit distinctly epithelial characteristics in their chondroid as well as their epithelial areas.
(12) A 99mTc-MDP scan was done on a patient with liver metastases from a medullary thyroid carcinoma who, in addition, had a familial history of multiple endocrine neoplasm, type 2.
(13) Two patients are described in whom Streptococcus bovis bacteremia was the only clue to the presence of a colonic neoplasm.
(14) Comparison with other neoplasms of the uterine cervix indicates that the lesion should be classified separately.
(15) The flounder developed renal and pancreatic neoplasms and hepatotoxic neoplastic precursor lesions, demonstrating trophic transfer of sediment-bound carcinogens up the food chain.
(16) Compared to related compounds, N-nitrosobis(2-hydroxypropyl)amine and N-nitrosobis(2-acetoxy-propyl)amine which are also pancreatic carcinogens, BOP induced only a few neoplasms of the lung, liver, and kidney and none in the nasal cavity, larynx, and trachea.
(17) Medullary carcinoma is an unusual malignant neoplasm.
(18) During the period of the study, 163 patients with primary intracranial neoplasms were seen and thus acoustic schwannomas accounted for 3.7%.
(19) We describe 2 additional cases, review the literature on this rare neoplasm and discuss its management.
(20) The neoplasm diagnosed as a neurinoma, was transplanted over 20 passages to 5 six-month-old Sprague-Dawley rats in each case.