(n.) The state or quality of being malignant; disposition to do evil; virulent enmity; malignancy; malice; spite.
(n.) Virulence; deadly quality.
(n.) Extreme evilness of nature or influence; perniciousness; heinousness; as, the malignity of fraud.
Example Sentences:
(1) In contrast to previous reports, these tumours were more malignant than osteosarcomas and showed a five-year survival rate of only 4-2 per cent.
(2) Oral administration in domestic cats causes malignant hepatomas and tumors of the esophagus and kidney.
(3) In view of reports of the reduction of telomeric repeats in human malignant tumors, we measured the lengths of telomeric repeats in 55 primary neuroblastomas.
(4) The frequency of gastric malignancies in the families of the women with gastric polyps was higher than in the controls and in men, 6.2, 3.1 and 2.4 percent, respectively (p less than 0.05, and p less than 0.025).
(5) In 60 rhesus monkeys with experimental renovascular malignant arterial hypertension (25 one-kidney and 35 two-kidney model animals), we studied the so-called 'hard exudates' or white retinal deposits in detail (by ophthalmoscopy, and stereoscopic color fundus photography and fluorescein fundus angiography, on long-term follow-up).
(6) The only localized tumors known to produce elevation of CEA above the levels observed in non malignant diseases are carcinomas of the large bowel and the pancreas.
(7) Normal cultured human epidermal melanocytes and melanoma cells derived from three different malignant melanomas were examined for synthesis of extracellular matrix components before and after treatment for one day with interferon-gamma, tumor necrosis factor-alpha, or both.
(8) The presence of these markers has facilitated the identification and characterization of the mononuclear cells in a number of animal and human lymphoid malignancies.
(9) Benign and malignant epithelial and soft tissue tumors of the skin were usually negatively stained with MoAb HMSA-2.
(10) HCT were classified by light microscopy as benign (n = 22), intermediate (n = 30), and malignant (n = 13).
(11) This case is unusual in that it demonstrated no malignant epithelium beyond that of a borderline tumor, but met the criteria of malignancy because of its invasiveness and metastasis.
(12) As novel antibody therapeutics are developed for different malignancies and require evaluation with cells previously uncharacterized as antibody-dependent cell-mediated cytotoxicity (ADCC) targets, efficient description of key parameters of the assay system expedites the preclinical assessment.
(13) The fragile site at 10q25 was expressed in larger proportions of malignant than normal cells.
(14) In the control group it was 18% and in other malignancies 20%.
(15) Total lactate dehydrogenase (LDH; EC 1.1.1.27) activity and the percentage distribution of LDH isoenzymes were determined in 127 patients with malignant diseases.
(16) In our opinion, a carcinologically "malignant" metastatic myxoma remains a questionable pathological entity.
(17) Hexokinase, phoshofructokinase, and aldolase appear to be rate-limiting in normal cervix epithelium; however, since the increase in activity of the first two in cancers was least of all the glycolytic enzymes, redundant enzyme synthesis probably occurs in the malignant cell for the enzymes catalysing reversible reactions.
(18) The flow cytometric measured DNA content (i.e., DNA index), S-fractions, and histopathologic malignancy grades were studied for ninety uterine cervical squamous cell carcinomas using tissue biopsies taken prior to radiotherapy.
(19) Changes in the plasma lipid composition are observed in patients and animals with malignancy and certain other diseases that are consistent with peroxidation of plasma lipoprotein lipids.
(20) It was difficult to assess the diagnosis of malignant mesothelioma on isolated differentiated mesothelial cells in pleural fluids or biopsies.
Rancor
Definition:
(n.) The deepest malignity or spite; deep-seated enmity or malice; inveterate hatred.
Example Sentences:
(1) In its more loose, common usage, it's a game in which the rivalry has come to acquire the mad, rancorous intensity of a Celtic-Rangers, a Real Madrid-Barcelona, an Arsenal-Tottenham, a River Plate-Boca Juniors.
(2) The developments come at a time of deep tension in Bangladesh , a nation struggling to overcome extreme poverty and rancorous politics.
(3) No one else need bother to paint them as a ramshackle and rancorous rabble marooned in the past and without a plausible account of the future.
(4) Arguments about this case, and the broader debate about the best way to tackle exploitative treatment of women in the sex industry, are unexpectedly rancorous.
(5) Trump approves of working with autocrats, at least, and would probably make fast friends with the galaxy’s less reputable leaders – especially those who share his interests, eg crimelord Jabba the Hutt, who lives in an ostentatious palace , loves parties , demeans women and feeds a literal Rancor .
(6) A sense of victimhood festers among even relatively advantaged white men, as the rancorously popular candidacy of Donald Trump confirms.
(7) This peaceful university town is 7,000 miles from the violence of the Middle East, but a proposal to become sister cities with a Palestinian community has stirred such rancor that the city council is trying to negotiate a truce among its own residents.
(8) While the contest has at times been rancorous, there is now a degree of bonhomie among the contenders – an esprit de corps that arises from having shared stages, green rooms and cars non-stop for nearly four months.
(9) Under Pinter's direction, Bates brilliantly brought out Butley's blend of rancorous wit and emotional immaturity; and it was to be the start of a long and fruitful assocation with Gray that included the lead roles in Otherwise Engaged (1975), for which Bates won an Evening Standard Best Actor award, Stage Struck (1979) and Melon (1987).
(10) That we demand a contest as satisfyingly unwholesome and rancorous as Cain and Abel, not something as nauseatingly wholesome and harmonious as Abel and Cole?
(11) Even in the most partisan and rancorous of times in Washington, there was enough respect for the two-party system and voters to avoid such an arrogant and autocratic move.
(12) Negotiations between the two sides have gone nowhere for five months and have become particularly rancorous in the past month as bailout and debt repayment deadlines came and went, with Athens missing a €1.5bn repayment to the IMF.
(13) Keegan haunts Ashley Mike Ashley, the Newcastle United owner, looks like he has learned the lessons of Kevin Keegan's rancorous 13-month battle for compensation after he was constructively dismissed as Newcastle manager in September 2008.
(14) That spirit of forgiveness is what we need more and more in this rancorous modern world.” The opposition leader, Bill Shorten, said the fresh calls for changes to the Racial Discrimination Act were a “ distasteful” attempt to use the French attack “to make domestic political points in Australia”.
(15) With Washington gripped by a growing sense that it may be too late to avert a crisis, the president has said he will give the increasingly rancorous negotiations until the end of next week to reach agreement on the terms for raising the US's $14.3 trillion (£8.9tn) debt ceiling.
(16) Photograph: Reuters The debate about restoring affordability to our cities is often rancorous and out of date.
(17) The legislation had an agonisingly tortuous passage through a rancorous and partisan Congress, but eventually it made it onto the statute book.
(18) John Gielgud highlighted Hamlet’s lyrical introspection, Laurence Olivier his athletic virility, Nicol Williamson his rancorous disgust, Mark Rylance his tormented isolation, David Tennant his mercurial humour.
(19) Thus, the usual forms of working time organization, with their arbitrary divisions, the monotony, repetitiveness and other restricting factors (stress), not only do not contribute to self-realization, but create rancor, boredom and drama.
(20) Barrett offers conciliation after a year and a half of unprecedented partisan rancor and disruptive political turmoil.