(1) This substance stopped fetal and skin (MALME 3 line) fibroblast propagation.
(2) In maxicells, the resulting plasmid permitted tac12-promoted synthesis of two polypeptides, encoded by gene malM, with apparent molecular weights of 37 X 10(3) and 34.5 X 10(3).
(3) Smaller increases were noted with the cell lines RPMI 7951, HT 144, Malme-3M, MEL-2, and no significant increase was observed with MEL-5.
(4) Treatment of MALME-3 cells with BESPM resulted in an accumulation of N-acetylspermidine in cells and the enhanced excretion of putrescine, spermidine, and N-acetylspermidine into the medium.
(5) The malM gene, encoding a periplasmic protein of unknown function in Escherichia coli, is a highly conserved as genes encoding proteins of known function from the same region.
(6) Treatment of human MALME-3 melanoma cells with 10 microM N1,N11-bis(ethyl)norspermine (BENSPM) for 48-72 h increased SSAT activity by some 1000- to 4000-fold and enabled purification of the enzyme by established procedures--binding on immobilized spermine and elution with spermine followed by binding on Matrex Blue A and elution with coenzyme A.
(7) One malM mutation corresponding to an A.T----G.C transition showed a 10-fold-higher spontaneous reversion frequency than other such transitions in a wild-type background.
(8) From 1981, we changed a surgical procedure fro Gersony-Malm procedure to the posterior approach method, and a surgical technique from the deep hypothermia and the circulatory arrest to the moderate hypothermia and the pump perfusion.
(9) The patient was treated with repair using Gersony-Malm's method and plasty of SVC because of the stenosis of the common pulmonary vein's entrance to the SVC.
(10) In MALME-3 cells, SSAT accumulation was found to be differentially modulated by the BESPM homologues, N1,N11-bis-(ethyl)norspermine and N1,N14-bis-(ethyl)homospermine, which were 5-fold more and 9-fold less effective, respectively, than BESPM in increasing SSAT but similar in analogue uptake and effects on polyamine biosynthesis and cell growth inhibition.
(11) The intergenic region between lamB and the following gene, malM, comprises conserved segments, including one palindromic unit.
(12) They result in an increase in amount and specific activity of a MalM-LacZ hybrid protein.
(13) The complete malM open reading frame was cloned under control of the tac 12 promoter.
(14) Mutations affecting the hydrophobic core of the N-terminal extension of the MalM protein have been isolated.
(15) The calcium balance studies of Malm were re-analysed to quantify the seasonal variation he had demonstrated in one group of men.
(16) We show that the chromosomal malM gene is expressed as part of the malK-lamB operon, and that its product is periplasmic.
(17) Antiproliferative effects ranged from slowing of cell growth in the less SSAT responsive lines (LOX, SH-1) to total cessation of cell growth or overt cytotoxicity in the more potently SSAT responsive lines (MALME-3, Ebey).
(18) Finally, we demonstrate with nuclease S1 mapping experiments that the mRNA terminates at a typical rho-independent terminator located about 45 base-pairs beyond the end of gene malM, which is thus the last gene of the malK-lamB operon.
(19) We have subcloned and sequenced the genes malF and malM of Salmonella typhimurium, thereby completing the determination of the nucleotide sequence of its 'maltose B' regulon.
(20) They failed to kill autologous B cells, erythroid progenitors present in allogeneic bone marrow, and a number of cultured human tumor cells (Malme, CAKI) even after prolonged (36 h) co-culture.
Mam
Definition:
(n.) Mamma.
Example Sentences:
(1) PFP-MAM is separated by capillary GC and identified mass spectrometrically by selected ion monitoring (SIM).
(2) In this study the morphology of the lateral geniculate nucleus and occipital cortex in rats with methylazoxymethanol acetate (MAM Ac)-induced micrencephaly was examined.
(3) The use of monoclonal antibodies and alpha MAM-6 indicated that the majority of TEC were of medullary origin.
(4) The results suggest that rats exposed to MAM in varying doses would be useful for evaluating the developmental process of neurons and its unification.
(5) Also analogues seem to be the producing of the so-called instinctives as mam(m)a and papa by somewhat older babies which are able to pass over from the babbling into permanent words of the adults' speech in which they persist if used without shifting of sounds since they are produced de novo generation by generation, but they are subordinate to shifting and possible extinction if used in the form of derivatives in the standard language, and some phenomena of the phylogenesis as the survival of less differentiated species contrary to the relatively quick extinction of the highly specialized ones.
(6) Liver microsomes isolated from rats fed the 3 diets metabolized MAM to formic acid and methanol in vitro, but liver microsomes from rats fed the continuous ethanol diet were 12 to 15 times more active than liver microsomes from rats fed the control diet.
(7) Too proud to ask for help, the alarm bells rang in the week before his death when he accepted a tenner from his mam.
(8) A quantitative sandwich radioimmunoassay, using 115D8 as catcher and as tracer antibody, has been developed to detect MAM-6 in serum.
(9) To further analyze the apparent colocalization of ricin and MAM-6 in the perinuclear Golgi region, immunogold cytochemistry on ultracryosections was performed.
(10) The brain weights in the MNU- and MAM-treated pups on postnatal day 22 were significantly less than those in the control pups.
(11) MAM-6 might be considered as a marker of severe (premalignant) dysplasia in adenomas of the large intestine.
(12) Microradiographical and histological investigations showed that the cranial base lordosis was more pronounced in the MAM rats than in the controls, and that the width of the spheno-occipital synchondrosis was reduced mainly due to reduction in the central zone.
(13) These results suggest that working memory disorders of MAM rats on radial maze tasks may be due to the lowering of cholinergic functions in their hippocampus and cerebral cortex.
(14) Cumulative properties indicate that MAM is the guinea pig analogue of human Mo1 and mouse Mac-1.
(15) The controls of a fibroblastic cell culture derived from gill tissue of bluegill sunfish showed spontaneous transformation after 6 months of passage, similar to the transformation observed in the experimental MAM acetate treated gill cultures.
(16) One of the antigens, MAM-6, appeared to be an important epithelial marker, present in all normal and neoplastic breast tissue samples, in about 80% of non-mammary normal tissues and in more than 90% of non-mammary epithelial tumours.
(17) Pretreatment with CCl4 caused not only early death from chemical toxicity of MAM but also an increase in small-bowel tumors.
(18) Unlike paramagnetic material, MAM appears effective as a small-bowel contrast material.
(19) 5HT-immunoreactive neurons in the MAM-rats were reduced in number and irregularly distributed in the dorsal and median raphe nuclei compared with those in the control.
(20) Treatment with MAM, 3 to 6 hr after Con A addition, partially blocks the enhancement.