(1) This substance stopped fetal and skin (MALME 3 line) fibroblast propagation.
(2) In maxicells, the resulting plasmid permitted tac12-promoted synthesis of two polypeptides, encoded by gene malM, with apparent molecular weights of 37 X 10(3) and 34.5 X 10(3).
(3) Smaller increases were noted with the cell lines RPMI 7951, HT 144, Malme-3M, MEL-2, and no significant increase was observed with MEL-5.
(4) Treatment of MALME-3 cells with BESPM resulted in an accumulation of N-acetylspermidine in cells and the enhanced excretion of putrescine, spermidine, and N-acetylspermidine into the medium.
(5) The malM gene, encoding a periplasmic protein of unknown function in Escherichia coli, is a highly conserved as genes encoding proteins of known function from the same region.
(6) Treatment of human MALME-3 melanoma cells with 10 microM N1,N11-bis(ethyl)norspermine (BENSPM) for 48-72 h increased SSAT activity by some 1000- to 4000-fold and enabled purification of the enzyme by established procedures--binding on immobilized spermine and elution with spermine followed by binding on Matrex Blue A and elution with coenzyme A.
(7) One malM mutation corresponding to an A.T----G.C transition showed a 10-fold-higher spontaneous reversion frequency than other such transitions in a wild-type background.
(8) From 1981, we changed a surgical procedure fro Gersony-Malm procedure to the posterior approach method, and a surgical technique from the deep hypothermia and the circulatory arrest to the moderate hypothermia and the pump perfusion.
(9) The patient was treated with repair using Gersony-Malm's method and plasty of SVC because of the stenosis of the common pulmonary vein's entrance to the SVC.
(10) In MALME-3 cells, SSAT accumulation was found to be differentially modulated by the BESPM homologues, N1,N11-bis-(ethyl)norspermine and N1,N14-bis-(ethyl)homospermine, which were 5-fold more and 9-fold less effective, respectively, than BESPM in increasing SSAT but similar in analogue uptake and effects on polyamine biosynthesis and cell growth inhibition.
(11) The intergenic region between lamB and the following gene, malM, comprises conserved segments, including one palindromic unit.
(12) They result in an increase in amount and specific activity of a MalM-LacZ hybrid protein.
(13) The complete malM open reading frame was cloned under control of the tac 12 promoter.
(14) Mutations affecting the hydrophobic core of the N-terminal extension of the MalM protein have been isolated.
(15) The calcium balance studies of Malm were re-analysed to quantify the seasonal variation he had demonstrated in one group of men.
(16) We show that the chromosomal malM gene is expressed as part of the malK-lamB operon, and that its product is periplasmic.
(17) Antiproliferative effects ranged from slowing of cell growth in the less SSAT responsive lines (LOX, SH-1) to total cessation of cell growth or overt cytotoxicity in the more potently SSAT responsive lines (MALME-3, Ebey).
(18) Finally, we demonstrate with nuclease S1 mapping experiments that the mRNA terminates at a typical rho-independent terminator located about 45 base-pairs beyond the end of gene malM, which is thus the last gene of the malK-lamB operon.
(19) We have subcloned and sequenced the genes malF and malM of Salmonella typhimurium, thereby completing the determination of the nucleotide sequence of its 'maltose B' regulon.
(20) They failed to kill autologous B cells, erythroid progenitors present in allogeneic bone marrow, and a number of cultured human tumor cells (Malme, CAKI) even after prolonged (36 h) co-culture.
Mixture
Definition:
(n.) The act of mixing, or the state of being mixed; as, made by a mixture of ingredients.
(n.) That which results from mixing different ingredients together; a compound; as, to drink a mixture of molasses and water; -- also, a medley.
(n.) An ingredient entering into a mixed mass; an additional ingredient.
(n.) A kind of liquid medicine made up of many ingredients; esp., as opposed to solution, a liquid preparation in which the solid ingredients are not completely dissolved.
(n.) A mass of two or more ingredients, the particles of which are separable, independent, and uncompounded with each other, no matter how thoroughly and finely commingled; -- contrasted with a compound; thus, gunpowder is a mechanical mixture of carbon, sulphur, and niter.
(n.) An organ stop, comprising from two to five ranges of pipes, used only in combination with the foundation and compound stops; -- called also furniture stop. It consists of high harmonics, or overtones, of the ground tone.
Example Sentences:
(1) Stimulation is also observed with mixtures of APC expressing DPw3 and APC expressing A1, and likewise, DPw3+ APC become stimulatory when preincubated with supernatants from A1-positive cells.
(2) Fluorination with [18F]acetylhypofluorite yields 6-[18F]fluoro-L-dopa with 95% radiochemical purity; fluorination of the same substrate with [18F]F2 yields a mixture of all three structural isomers in a ratio of 70:16:14 for 6-, 5-, and 2-fluoro compounds.
(3) In addition to the phase diagrams reported here for these two binary mixtures, a brief theoretical discussion is given of other possible phase diagrams that may be appropriate to other lipid mixtures with particular consideration given to the problem of crystalline phases of different structures and the possible occurrence of second-order phase transitions in these mixtures.
(4) However, within 5 min potassium overcame the vanadate potentiation of ouabain binding regardless of the order in which it was added to the reaction mixture.
(5) Mixtures of 2 components involving kappa-casein were more readily dephosphorylated than alphas- and beta-casein mixtures.
(6) None of the animals injected with either CD4+ or CD8+ T cells became overtly diabetic during the 30 days of observation whereas 8 of 23 mice inoculated with a mixture of the two subsets developed glycosuria and hyperglycemia.
(7) The hypothesis that experimentally determined survival times of Treponema pallidum in stored donor blood could be related to the number of treponemes initially present in the treponeme-blood mixtures was investigated by inoculating rabbits with three graded doses of treponemes suspended in donor blood and stored at 4 degrees C for various periods of time.
(8) The IL-8 isolated from each of these cell types is a mixture of two IL-8 polypeptides, one consisting of 72 amino acids (herein called [ser-IL-8]72) and the other 77 amino acids (an N-terminal extended form herein called [ala-IL-8]77).
(9) Differential absorption experiments showed that LG-1 contained a mixture of specific and cross-reacting antibodies.
(10) The method involves the use of a monoclonal antibody fragment mixture that binds to platelets.
(11) It is shown that, by comparison of a reacting mixture at chemical equilibrium with a non-reacting but equally composed one, the sum of the mean concentrations of the reaction products can immediately be taken from optical absorption or from interferometric measurements.
(12) The 105 000 X g supernatant of the reaction mixture, which contained more than 85% of the thiobarbituric acid-reactive substances, did not inactivate the plasmid DNA.
(13) Blood acid-base status, serum electrolytes, and urine pH were examined in 64 infants and children with phenylketonuria (PKU) treated with three different low phenylalanine protein hydrolyzates (Aponti, Cymogran, AlbumaidXP) and two synthetic amino acid mixtures (Aminogran, PAM).
(14) Anaesthesia was achieved by a mixture of oxygen, nitrous oxide and fluothane without use of muscle relaxants.
(15) Variations in light chain composition, particularly fast and slow myosin light chain 1, appeared to occur independently of the variations in heavy chain composition, suggesting that some myosin molecules consist of mixtures of slow- and fast-type subunits.
(16) That piece was placed on the slide and embedded with a mixture of agar and antiserum.
(17) In addition, a beta-linked sialic acid:nucleoside conjugate (Kl-8111) and an equimolar mixture of Kl-8110 and Kl-8111 (Kl-414) also inhibited the metastatic ability of NL cells to the same extent as Kl-8110 did.
(18) In contrast, boundary layer diffusion is operative in the release from the matrixes prepared by compression of physical mixtures.
(19) The bacterial strains did not liberate free patulin from the adduct mixture present in the growth medium.
(20) (Tokyo) 58, 227), yields a protein mixture that has a time-dependent 13C-NMR spectrum.