(a.) Various in kind or quality; many in number; numerous; multiplied; complicated.
(a.) Exhibited at divers times or in various ways; -- used to qualify nouns in the singular number.
(n.) A copy of a writing made by the manifold process.
(n.) A cylindrical pipe fitting, having a number of lateral outlets, for connecting one pipe with several others.
(n.) The third stomach of a ruminant animal.
(v. t.) To take copies of by the process of manifold writing; as, to manifold a letter.
Example Sentences:
(1) Combined hypertension treatment with inhibitors of the converting enzyme (ICE) and diuretocs gives manifold advantages, the most important of them is a synergistic action of both drugs resulting in blood pressure decrease and prevention of hypokaliaemia.
(2) It is stressed that the exact anatomical diagnosis requires the examination of every segment which can be performed only by using manifold planes.
(3) An anaerobic sampling manifold withdrew 19 samples of blood during the rest-to-exercise transition; sampling interval was usually 4 s. Blood gas analysis showed that, on average, from rest-to-steady-state exercise, O2 saturation (Svo2) fell from 71 to 41% and mixed venous PCO2 (PvCO2) rose from 42 to 59 Torr.
(4) These induction periods are regarded as the time needed by far-from-equilibrium fluctuations to drive the system into the center manifold.
(5) The apparent Km of the modified enzyme for soluble starch increased manifold, thus implicating the sensitive tryptophan residue in the substrate binding region of the enzyme.
(6) All image vectors were orthonormalized to span a linear manifold.
(7) A manifold for rapid determination of fluoride has been designed that uses a single coil for complex formation and extraction.
(8) Impinger samples were collected from the sampling manifold and analyzed accordingly.
(9) This manifold can be used to validate or calibrate various industrial hygiene analyses such as charcoal and detector tube technology, impinger techniques, respirator cartridge testing, and various survey instruments.
(10) The presentation of SAS may be manifold, and the primary health care teams play a crucial role in the detection of their basic symptoms.
(11) The modification can be made in less than 4 h without the need for any additional parts; the modified manifold requires one-third fewer pump lines and fewer reagents, thus reducing operating costs and simplifying instrument maintenance, while retaining the same precision, speed, low carryover, and linearity of the production model.
(12) The low-field temperature dependence of the MCD of oxidized FdI, which originates in the paramagnetic oxidized [3Fe-4S]1+ cluster, establishes the absence of a significant population of excited electronic states of this cluster up to 60 K. The low-field temperature dependence of the MCD of reduced FdI establishes that the ground-state manifold of the reduced [3Fe-4S]0 cluster possesses S greater than or equal to 2 at both pH 6.0 and 8.3.
(13) The appearance of this disease as generalized vasculitis is conditioned by the manifold clinical symptomatology and thus renders the diagnostics extraordinarily difficult.
(14) After certain modifications had been made in the manifold, satisfactory degrees of accuracy were also obtained for the erythrocyte counts.
(15) Among the manifold immunologic events which take place during parasitic invasions, production of autoantibodies and immune complexes can play a serious role during infections with African and American trypanosomes.
(16) There are manifold specific causes of death characterized by conditions manifest in middle and late life.
(17) It is now customary practice to couple separately metered infusions via a manifold to a common catheter that enters the patient.
(18) The differential diagnoses was manifold because of the traveling habits, the clinical symptomatic and the course of the disease.
(19) Their information must be transduced through binding to membrane receptors, so as to elicit the appropriate biological response from the manifold repertoire of a cell.
(20) The enzyme can be seen as strategically located to play a role in regenerating ATP required for the manifold activities of the synaptic membrane.
Topology
Definition:
(n.) The art of, or method for, assisting the memory by associating the thing or subject to be remembered with some place.
Example Sentences:
(1) The scheme is based on topological information, i.e.
(2) These results provide knowledge of the interrelationships between antibiotic and substrate ribosome binding sites which should eventually contribute to a map of ribosomal topology.
(3) The conformational properties of these new TASPs are now under investigation, with special emphasis on the relationship between overall conformation and the nature of the topological template.
(4) In the context of a simplified diamond lattice model of a six-member, Greek key beta-barrel protein that is closely related in topology to plastocyanin, the nature of the folding and unfolding pathways have been investigated using dynamic Monte Carlo techniques.
(5) At the Second Scandinavian Congress on Image Analysis in 1981 Kohonen provided evidence that the map of signals has the same topological order as the map of reactions.
(6) Phylogenetic analysis of the aligned sequences by both phenetic and cladistic methods with H. perryi as an outgroup generated one best topology which pairs S. alpinus with S. malma as the most recently derived species, and pairs S. confluentus with S. leucomaenis.
(7) Then, a 'hyperstructure matrix' is generated, containing the unique topological relationship between every pair of regions.
(8) Linear DNA substrates in which pairing is topologically restricted to a paranemic joint also follow this relationship.
(9) The subgroups of carcinoma of the bladder, determined by topology, have markedly different long-term prognoses.
(10) The fluorescence properties of Hoechst 33342 (HO 33342) were examined with plasmid pBR322 in the supercoiled (Form I) or relaxed covalently closed circular (Form Io) conformation in order to determine whether qualitative or quantitative differences in fluorescence properties might provide an assay for topological states of DNA.
(11) An exhaustive search of all possible trees also supported this topology, although one haplotype had to be eliminated from this analysis to save computer time.
(12) This superfamily of proteins is predicted to share the topology of the seven transmembrane helices of bacteriorhodopsin (BR), even though no significant sequence homology had been identified.
(13) These data demonstrate the utility of this approach for determining membrane protein topology and extend potential applications to include at least some proteins not normally expressed in E. coli.
(14) The unique topology of the products indicates that resolvase fixes the sum of the number of supercoils between recombination sites at synapsis and the number of such supercoils lost or gained during strand exchange.
(15) Such explanations are possible because the relatively few structural proteins of the erythrocyte are regularly distributed over the entire cytoplasmic surface of the cell membrane and because the well-understood topological associations of these proteins seem to be stable in comparison with the time required for the cell to change shape.
(16) The objectives of the present investigations were to document a composite, new approach for the evaluation of the structure-function dependencies of proteins based on the analysis of the informational content of the primary amino acid sequence as well as the topological and functional regions of a protein.
(17) When the input topology is supercoiled, high levels of transcription are observed, whereas input relaxed DNA is transcribed to a much lower extent.
(18) It is believed that one or more basic residues at the extreme amino terminus of precursor proteins and the lack of a net positive charge immediately following the signal peptide act as topological determinants that promote the insertion of the signal peptide hydrophobic core into the cytoplasmic membrane of Escherichia coli cells with the correct orientation required to initiate the protein export process.
(19) We observe that the effect of osmotic shock is an elevation of superhelical tension; quantitative comparison with changes in plasmid linking number indicates that the alteration in DNA topology is all unconstrained.
(20) Anomalous correspondence most probably has its seat where the retinal topology is not exact, i.e., where the binocular receptive fields are very large and encompass the corpus callosum, such as in area 20 or 21.