(n.) The style of writing or thought of an author; characteristic peculiarity of an artist.
(n.) Certain degree or measure; as, it is in a manner done already.
(n.) Sort; kind; style; -- in this application sometimes having the sense of a plural, sorts or kinds.
Example Sentences:
(1) Results suggest that Cd-MT is reabsorbed and broken down by kidney tubule cells in a physiological manner with possible subsequent release of the toxic cadmium ion.
(2) These data indicate that CSF levels are not inversely related to the blood neutrophil count in chronic idiopathic neutropenia and suggest that CSF is not a hormone regulating the blood neutrophil count in a manner analogous to the erythropoietin regulation of circulating erythrocyte levels.
(3) Diazepam inhibited DA release evoked by high concentrations of extracellular K+ in a dose-dependent manner (IC50, 10 microM).
(4) Somatostatin inhibited carbachol- and cholecystokinin octapeptide-induced pepsinogen secretion from dispersed gastric mucosal cells in a dose-dependent manner.
(5) The amplitudes of the a-wave and the 01 decreased in dose-dependent manners, but their changes were less striking than those of the 01 latency.
(6) A neodymium YAG (Nd:YAG) laser was evaluated in a dog ulcer model used in the same manner as is recommended for bleeding patients (power 55 W, divergence angle 4 degrees, with CO2 gas-jet assistance).
(7) Hemagglutinating (HA) activity of rubella virus was inactivated with 2-mercaptoethanol (2ME) in a dose-dependent manner.
(8) Enzyme prepared in this manner was homogeneous according to electrophoresis on sodium dodecyl sulfate-polyacrylamide gels and immunoelectrophoresis using antiserum directed against it.
(9) Loss of reduced protein thiols, as measured by binding of the thiol reagent iodoacetic acid to GPD, and loss of GPD enzymatic activity occurred in a dose-dependent manner.
(10) Inhibition of binding of [3H]TPA to the receptor preparation by tigliane and ingenane DTE correlates with irritant activity in vivo, while some daphnane and 1 alpha-alkyldaphnane DTE inhibit binding of [3H]TPA in a less pronounced manner but still are very irritant.
(11) All three organotins inhibited cardiac Na+,K(+)-ATPase, [3H]ouabain binding, K(+)-activated p-nitrophenyl phosphatase (K(+)-PNPPase) and oligomycin-sensitive (OS) and oligomycin-insensitive (OI) Mg(2+)-ATPase in a concentration-dependent manner.
(12) "With the advent of sophisticated data-processing capabilities (including big data), the big number-crunchers can detect, model and counter all manner of online activities just by detecting the behavioural patterns they see in the data and adjusting their tactics accordingly.
(13) The reductase in B. subtilis seemed to reduce ribonucleoside triphosphates in a similar manner to the enzyme in Lactobacillus leichmannii.
(14) At high luminances, the temporal, but not spatial, properties of this mechanism break down in a manner which had not been studied.Low-frequency inhibitory processThis process is manifest as a decrease in sensitivity from that of the simple excitatory process.
(15) Dialyzed crude enzyme extracts from yeast cells were found to destroy diacetyl in a manner quite similar to that of diacetyl reductase from Aerobacter aerogenes, and both the bacterial and the yeast extracts were stimulated significantly by the addition of reduced nicotinamide adenine dinucleotide (NADH).
(16) The liposomal thyroglobulin was hydrolyzed in a time-dependent manner in the fraction showing both radioactivity and acid phosphatase activity.
(17) The dual-probe system incorporates a central collimated probe for monitoring activity in the LV surrounded by an annular detector collimated in such a manner as to provide simultaneous real-time monitoring of the LV background activity.
(18) Cell culture experiments showed that CA III induced a 2- to 11-fold increase in [14C]HA synthesis by human synovial fibroblasts (SF) in a dose-dependent manner (P less than 0.001); erythrocyte CA I and CA II were inactive.
(19) Dopamine and SKF 82526 stimulated the release of inositol phosphates from added [3H]PIP2 in a concentration-dependent manner.
(20) We found that when CyA or FK was added to the culture throughout the experiment, the production of the factors with ECA by PBMC was inhibited in a dose-dependent manner.
Tone
Definition:
(n.) Sound, or the character of a sound, or a sound considered as of this or that character; as, a low, high, loud, grave, acute, sweet, or harsh tone.
(n.) Accent, or inflection or modulation of the voice, as adapted to express emotion or passion.
(n.) A whining style of speaking; a kind of mournful or artificial strain of voice; an affected speaking with a measured rhythm ahd a regular rise and fall of the voice; as, children often read with a tone.
(n.) A sound considered as to pitch; as, the seven tones of the octave; she has good high tones.
(n.) The larger kind of interval between contiguous sounds in the diatonic scale, the smaller being called a semitone as, a whole tone too flat; raise it a tone.
(n.) The peculiar quality of sound in any voice or instrument; as, a rich tone, a reedy tone.
(n.) A mode or tune or plain chant; as, the Gregorian tones.
(n.) That state of a body, or of any of its organs or parts, in which the animal functions are healthy and performed with due vigor.
(n.) Tonicity; as, arterial tone.
(n.) State of mind; temper; mood.
(n.) Tenor; character; spirit; drift; as, the tone of his remarks was commendatory.
(n.) General or prevailing character or style, as of morals, manners, or sentiment, in reference to a scale of high and low; as, a low tone of morals; a tone of elevated sentiment; a courtly tone of manners.
(n.) The general effect of a picture produced by the combination of light and shade, together with color in the case of a painting; -- commonly used in a favorable sense; as, this picture has tone.
(v. t.) To utter with an affected tone.
(v. t.) To give tone, or a particular tone, to; to tune. See Tune, v. t.
(v. t.) To bring, as a print, to a certain required shade of color, as by chemical treatment.
Example Sentences:
(1) The vascular endothelium is capable of regulating tissue perfusion by the release of endothelium-derived relaxing factor to modulate vasomotor tone of the resistance vasculature.
(2) In summary, GABAergic tone did not effect basal acid secretion in anesthetized rats.
(3) After midazolam infusion, there was a 50% decrease in amplitude of P3 in response to target tones (P less than 0.006), whereas N3 latency increased by 40 ms (P less than 0.05).
(4) All of this in the same tones of weary nonchalance you might use to stop the dog nosing around in the bin.
(5) More disturbing than his ideas was Malema's style and tone.
(6) Noradrenaline decreased the phasic contraction amplitude of the circular muscle and exerted a stimulant effect on the tone which suggested an existence of two alpha 1-adrenoceptor subtypes.
(7) Histamine (10(-6)-10(-4) M) induced concentration-dependent increases in tone and Ca2+i, but these responses were not sustained.
(8) Masking experiments are demonstrated for electrical frequency-modulated tone bursts from 1,000 to 10,000 cps and from 10,000 to 1,000 cps with superimposed clicks.
(9) The stimuli were two simple tones in experiment 1 and two tonal complexes in both experiments 2 and 3.
(10) Isolated outer hair cells from the organ of Corti of the guinea pig have been shown to change length in response to a mechanical stimulus in the form of a tone burst at a fixed frequency of 200 Hz (Canlon et al., 1988).
(11) Complex tones containing the first 20 harmonics of 50, 100, or 200 Hz, all at equal amplitude, were used.
(12) An attempt to eliminate the age effect by adjusting for age differences in monaural shadowing errors, fluid intelligence, and pure-tone hearing loss did not succeed.
(13) Inhibition of the production or action of these substances will allow for vasodilatation, and it is probable that perinatal pulmonary vascular tone reflects a balance between local prostaglandin and leukotriene production.
(14) Subject evaluations in accordance with the intensity levels of tones, i.e.
(15) Maximum expiratory flow on partial flow-volume curve at 25% forced vital capacity (PEF25) was measured as an index showing basal bronchomotor tone.
(16) Twenty-four hours later, a stimulus generalization test was conducted in the absence of drug; during this session, tones that varied in frequency around 4.5 KHz were presented while the animals were responding under the VI schedule.
(17) Auditory sensory perception was operationalized as number of tones heard on audiometric examination.
(18) Later, Lucas, also a former party leader, strongly defended Bennett, saying it was a “bad day for Natalie” but there was also “kind of a gloating tone that strikes one as having something to do with her being a woman in there too”.
(19) From a set of tones that varied only in intensity, it was possible to calculate the growth of loudness with intensity for the budgerigar.
(20) Two hundred forty-six fetuses had at least one abnormal biophysical profile variable with the risk of bad outcome, for a single abnormal variable, ranging from 8% (body movements) to 100% (tone) and increasing from 14% (any variable abnormal) to 63% (all variables abnormal).