(n.) A border; edge; brink; verge; as, the margin of a river or lake.
(n.) Specifically: The part of a page at the edge left uncovered in writing or printing.
(n.) The difference between the cost and the selling price of an article.
(n.) Something allowed, or reserved, for that which can not be foreseen or known with certainty.
(n.) Collateral security deposited with a broker to secure him from loss on contracts entered into by him on behalf of his principial, as in the speculative buying and selling of stocks, wheat, etc.
(v. t.) To furnish with a margin.
(v. t.) To enter in the margin of a page.
Example Sentences:
(1) Blood pressure control was marginally improved during the study and it is thought possible that better patient compliance might explain this.
(2) Nine of the 12 long-term survivors showed lymph node metastasis and six of the 12 revealed cancer cells at the surgical margins.
(3) Fusiform cells were most concentrated along the lateral margin of the subnucleus interpolaris.
(4) But that gross margin only includes the cost of paying drivers as a cost of revenue, classifying everything else, such as operations, R&D, and sales and marketing, as “operating expenses”.
(5) Photograph: AP Reasons for wavering • State relies on coal-fired electricity • Poor prospects for wind power • Conservative Democrat • Represents conservative district in conservative state and was elected on narrow margins Campaign support from fossil fuel interests in 2008 • $93,743 G K Butterfield (North Carolina) GK Butterfield, North Carolina.
(6) Computed tomography (CT) is the most sensitive radiologic study for detecting these tumors, which usually are small, round, sharply marginated, and of homogeneous soft tissue density.
(7) Although patients treated with postoperative radiation therapy showed significantly extended survival rates as compared to those receiving surgical resection alone, the glioblastoma recurred within a 2cm margin of the primary site in more than 90% of the patients and conventional external radiation therapy with a doses of 50-60 Gy did not result in local cure.
(8) Such margins would be enough to put the first female president in the White House, but Democrats are guarding against complacency.
(9) When collateral marginal vessels were eliminated, adjacent arterial blood flow decreased to control levels and venous flow virtually stopped.
(10) Measurements were made of the width of the marginal gap for three sites at each of four stages: (1) after the shoulder firing, (2) after the body-incisal firing, (3) after the glaze firing, and (4) after a correction firing.
(11) The ruffles of the sub-marginal cells showed different characteristics, being longer and not propagated successively as were the marginal ruffles.
(12) Based on review examination of 224 patients 5 years after their ankle fractures, the authors demonstrate a significant worsening of prognosis with fractures of the anterior or posterior tibial margin.
(13) Chloroquine concentrations were marginally but significantly higher in venous whole blood.
(14) Sialomucin was markedly increased in 17.0 percent of proximal resection margins and 17.3 percent in distal resection margins.
(15) The combined prevention of caries was conductive to improved treatment quality which was accounted for by a 1.5 to 2-fold reduction in the rate of disorders in marginal contact with filling material and secondary caries.
(16) The dietary information on children with diarrhea came from focus groups with mothers in 3 marginal urban communities, 3 rural indigenous communities, and 4 rural Ladino communities.
(17) After 21 days, supragingival and marginal plaque was collected from each subject and assayed for total cultivable microbiota, total facultative anaerobes, facultative Streptococci, Actinomyces, Fusobacterium, Veillonella and Capnocytophaga.
(18) Even when combined with a peripheral-acting BZD, such as Ro5-4608, which displayed only marginal antiproliferative activity against human melanoma cells when applied alone, growth suppression of the combination of this peripheral-type BZD with all three types of IFNs was more than additive.
(19) Suede sang about life on the margins, in council homes.
(20) The most important variable for anastomotic recurrence was mucin histochemical changes at the resection margins according to the Wald statistic value.
Tolerance
Definition:
(n.) The power or capacity of enduring; the act of enduring; endurance.
(n.) The endurance of the presence or actions of objectionable persons, or of the expression of offensive opinions; toleration.
(n.) The power possessed or acquired by some persons of bearing doses of medicine which in ordinary cases would prove injurious or fatal.
Example Sentences:
(1) within 12 h of birth followed by similar injections every day for 10 consecutive days and then every second day for a further 8 weeks, with mycoplasma broth medium (tolerogen), to induce immune tolerance.
(2) No differences between the two substances were observed with respect to side effects and general tolerability.
(3) This treatment is usually well tolerated but not devoid of systemic effects.
(4) Well tolerated from the clinical and laboratory points of view, it proved remarkably effective.
(5) To estimate the age of onset of these differences, and to assess their relationship to abdominal and gluteal adipocyte size, we measured adiposity, adipocyte size, and glucose and insulin concentrations during a glucose tolerance test in lean (less than 20% body fat), prepubertal children from each race.
(6) Although temazepam was effective for maintaining sleep with short-term use, there was rapid development of tolerance for this effect with intermediate-term use.
(7) testosterone, fentanyl, nicotine) may ultimately be administered in this way, important questions pertaining to pharmacology (tolerance), toxicity (irritation, sensitisation) and dose sufficiency (penetration enhancement) remain.
(8) There were no biochemical or haematological abnormalities caused by prazosin but on continued therapy 16 patients developed tolerance to its effect.
(9) Characerization of further parameters such as relative susceptibility to tolerance induction and relative degree of specificity was not possible with the use of KLH as the antigen.
(10) Because of these different direct and indirect actions, a sudden cessation of sinus node activity or sudden AV block may result in the diseased heart in a prolonged and even fatal cardiac standstill, especially if the tolerance to ischemia of other organs (notably the brain) is decreased.
(11) Efficacy and tolerability of perorally administered desmopressin were evaluated in 12 adult patients suffering from central diabetes insipidus.
(12) This suggests that both blood transfusion and allograft are required for IL2 suppression and that this suppression may be related to the heart tolerance.
(13) At present, ACE inhibitors are preferred because they are usually better tolerated than conventional vasodilators and are clinically more effective.
(14) Changes in pain tolerance after administration of differently labelled placebos were studied by measuring the reaction time after a cold stimulus.
(15) TK1 showed the most restricted substrate specificity but tolerated 3'-modifications of the sugar ring and some 5-substitutions of the pyrimidine ring.
(16) Provided that adequate reflection is given and the appropriate moment chosen, it is well tolerated and provides all the necessary information.
(17) After large bowel removal, there was impaired glucose tolerance and attenuated plasma insulin secretion.
(18) Cardiac pump function is not affected, even in patients with ventricular dysfunction or heart failure, in whom chronic oral administration of the drug is well tolerated.
(19) These agents have been well-tolerated and generally produce a high incidence of sustained improvements in neutrophil counts and marrow morphology, although hemoglobin and platelet counts have generally not been altered.
(20) The above treatment is tolerated well and no serious side effects have been observed.