(a.) Designated or distinguished by, or as by, a mark; hence; noticeable; conspicuous; as, a marked card; a marked coin; a marked instance.
Example Sentences:
(1) Herpesviruses such as EBV, HSV, and human herpes virus-6 (HHV-6) have a marked tropism for cells of the immune system and therefore infection by these viruses may result in alterations of immune functions, leading at times to a state of immunosuppression.
(2) Patient plasma samples demonstrated evidence of marked complement activation, with 3-fold elevations of C3a desArg concentrations by the 8th day of therapy.
(3) Following in vitro C activation in NHS by delta IgG, the 40 KD C4d component increased markedly.
(4) However, when cross-linked to anti-CD4 or anti-CD8 antibodies a markedly enhanced proliferation of the corresponding subpopulation is observed.
(5) When chimeric animals were subjected to a lethal challenge of endotoxin, their response was markedly altered by the transferred lymphoid cells.
(6) Increased dietary protein intake led to increased MDA per nephron, increased urinary excretion of MDA, and increased MDA per milligram protein in subtotally nephrectomized animals, and markedly increased the glutathione redox ratio.
(7) Cyclic AMP stimulated phosphorylation by [gamma-32P]ATP of two proteins of apparent Mr = 20,000 and 7,000 that were concentrated in sarcoplasmic reticulum, but the stimulation was markedly dependent on the presence of added soluble cyclic AMP-dependent protein kinase.
(8) Surprisingly, the clonal elimination of V beta 6+ cells is preceded by marked expansion of these cells.
(9) Muscle weakness and atrophy were most marked in the distal parts of the legs, especially in the gastrocnemius and soleus muscles, and then spread to the thighs and gluteal muscles.
(10) of PLA2 caused marked degranulation of mast cells in the rat mesentery which was facilitated by addition of calcium ion (10 mM) but antagonized by pretreating with three antiinflammatory agents.
(11) report the complications registered, in particular: lead's displacing 6.2%, run away 0.7%, marked hyperthermya 0.0%, haemorrage 0.4%, wound dehiscence 0.3%, asectic necrosis by decubitus 5%, septic necrosis 0.3%, perforation of the heart 0.2%, pulmonary embolism 0.1%.
(12) Marked enhancement of IFN-gamma production by T cells was seen in the presence of as little as 0.3% thymic DC.
(13) This effect was more marked in breast cancer patients which may explain our earlier finding that women with upper body fat localization are at increased risk for developing breast cancer.
(14) Completeness of isolation of the coronary and systemic circulations was shown by the marked difference in appearance times between the reflex hypotensive responses from catecholamine injections into the isolated coronary circulation and the direct hypertensive response from a similar injection when the circulations were connected as well as by the marked difference between the pressure pulses recorded simultaneously on both sides of the aortic balloon separating the two circulations.4.
(15) A marked overlap of input from the two eyes is an unusual feature for a diprotodont marsupial and has previously been seen only in the feathertail glider.
(16) The erythrocyte sedimentation rate is almost always markedly elevated.
(18) Sixteen patients (27%) manifested anomalies of the urinary tract: 12 had markedly altered kidneys, 8 of which were unilateral and ipsilateral to the diaphragmatic defect.
(19) Her muscle weakness and hyperCKemia markedly improved by corticosteroid therapy, suggesting that the diagnosis was compatible with polymyositis (PM).
(20) The introduction of intravenous, high-dose thrombolytic therapy during a brief period has markedly reduced mortality of patients with acute myocardial infarction.
Remarkable
Definition:
(a.) Worthy of being remarked or noticed; noticeable; conspicuous; hence, uncommon; extraordinary.
Example Sentences:
(1) The constitution of chromosomes in the two plasmacytomas remained remarkably stable in their homogeneous modal population.
(2) Well tolerated from the clinical and laboratory points of view, it proved remarkably effective.
(3) A remarkable deterioration of prognosis with increasing age rises the question whether treatment with cytotoxic drugs should be tried in patients more than 60 years old.
(4) Before issuing the ruling, the judge Shaban El-Shamy read a lengthy series of remarks detailing what he described as a litany of ills committed by the Muslim Brotherhood, including “spreading chaos and seeking to bring down the Egyptian state”.
(5) Research efforts in the Swedish schools are of high quality and are remarkably prolific.
(6) Recent research conducted by independent investigators concerning the relationship between crime and narcotic (primarily heroin) addiction has revealed a remarkable degree of consistency of findings across studies.
(7) Tiropramide remarkably increased cAMP level but it had no effect on cGMP level in the bladder at the lower concentrations.
(8) A remarkably close relationship was found between both H. pylori urease subunits and jack bean (Canavalia ensiformis) urease, the subunit of which is a single 840 amino acid polypeptide.
(9) Specific antibody patterns in vaccinees were highly variable and in a small number of subjects a remarkable antibody titre decrease was noticed.
(10) Gove, who touched on no fewer than 11 policy areas, made his remarks in the annual Keith Joseph memorial lecture organised by the Centre for Policy Studies, the Thatcherite thinktank that was the intellectual powerhouse behind her government.
(11) Four of the tumours, 2 adenomas and 2 intramucosal carcinomas, having a remarkable macroscopic appearance like a large mucosal fold are especially mentioned.
(12) During photoirradiation, both in vivo and in vitro, the serum polar (ZE)-bilirubin IX alpha concentration increased remarkably, but unbound-bilirubin values were not affected at all.
(13) Furthermore, the AMDP-3 scale and its manual constitute a remarkable teaching instrument for psychopathology, not always enough appreciated.
(14) The iPTH values found in the hemofiltrate were remarkably high, a finding that could be explained by non-specific effects, by the occurrence of hormone fragments or by an increased secretion rate.
(15) Both Apo AI (48%) and Apo AII (5.5%) were greatly diminished and Apo E was present in remarkably high amounts (39%) with two additional isoforms (Apo E'1 and Apo E'2).
(16) There was a remarkable tendency to newborns weighting more than 2000 g and a duration of pregnancy longer than 35 weeks.
(17) Results of the present study show that epithelial cells of ciliated columnar type covering vocal cords change remarkably to nonciliated squamous cells between prenatal and postnatal stages.
(18) Cyclosporine has a remarkable hepatotropic effect that may be helpful in the context of liver transplantation.
(19) This remarkably reliable examination showed a predominance of anterior and anterolateral aneurisms (87% of cases), and enables definition of the critical cardiac surface area (about 25%) above which the aneurysm is operable.
(20) The influential Belgian scientist Quetelet demonstrated a remarkable scotoma towards the phenomenon.