(a.) Designated or distinguished by, or as by, a mark; hence; noticeable; conspicuous; as, a marked card; a marked coin; a marked instance.
Example Sentences:
(1) Herpesviruses such as EBV, HSV, and human herpes virus-6 (HHV-6) have a marked tropism for cells of the immune system and therefore infection by these viruses may result in alterations of immune functions, leading at times to a state of immunosuppression.
(2) Patient plasma samples demonstrated evidence of marked complement activation, with 3-fold elevations of C3a desArg concentrations by the 8th day of therapy.
(3) Following in vitro C activation in NHS by delta IgG, the 40 KD C4d component increased markedly.
(4) However, when cross-linked to anti-CD4 or anti-CD8 antibodies a markedly enhanced proliferation of the corresponding subpopulation is observed.
(5) When chimeric animals were subjected to a lethal challenge of endotoxin, their response was markedly altered by the transferred lymphoid cells.
(6) Increased dietary protein intake led to increased MDA per nephron, increased urinary excretion of MDA, and increased MDA per milligram protein in subtotally nephrectomized animals, and markedly increased the glutathione redox ratio.
(7) Cyclic AMP stimulated phosphorylation by [gamma-32P]ATP of two proteins of apparent Mr = 20,000 and 7,000 that were concentrated in sarcoplasmic reticulum, but the stimulation was markedly dependent on the presence of added soluble cyclic AMP-dependent protein kinase.
(8) Surprisingly, the clonal elimination of V beta 6+ cells is preceded by marked expansion of these cells.
(9) Muscle weakness and atrophy were most marked in the distal parts of the legs, especially in the gastrocnemius and soleus muscles, and then spread to the thighs and gluteal muscles.
(10) of PLA2 caused marked degranulation of mast cells in the rat mesentery which was facilitated by addition of calcium ion (10 mM) but antagonized by pretreating with three antiinflammatory agents.
(11) report the complications registered, in particular: lead's displacing 6.2%, run away 0.7%, marked hyperthermya 0.0%, haemorrage 0.4%, wound dehiscence 0.3%, asectic necrosis by decubitus 5%, septic necrosis 0.3%, perforation of the heart 0.2%, pulmonary embolism 0.1%.
(12) Marked enhancement of IFN-gamma production by T cells was seen in the presence of as little as 0.3% thymic DC.
(13) This effect was more marked in breast cancer patients which may explain our earlier finding that women with upper body fat localization are at increased risk for developing breast cancer.
(14) Completeness of isolation of the coronary and systemic circulations was shown by the marked difference in appearance times between the reflex hypotensive responses from catecholamine injections into the isolated coronary circulation and the direct hypertensive response from a similar injection when the circulations were connected as well as by the marked difference between the pressure pulses recorded simultaneously on both sides of the aortic balloon separating the two circulations.4.
(15) A marked overlap of input from the two eyes is an unusual feature for a diprotodont marsupial and has previously been seen only in the feathertail glider.
(16) The erythrocyte sedimentation rate is almost always markedly elevated.
(18) Sixteen patients (27%) manifested anomalies of the urinary tract: 12 had markedly altered kidneys, 8 of which were unilateral and ipsilateral to the diaphragmatic defect.
(19) Her muscle weakness and hyperCKemia markedly improved by corticosteroid therapy, suggesting that the diagnosis was compatible with polymyositis (PM).
(20) The introduction of intravenous, high-dose thrombolytic therapy during a brief period has markedly reduced mortality of patients with acute myocardial infarction.
Waymark
Definition:
(n.) A mark to guide in traveling.
Example Sentences:
(1) There are ancient tracks and waymarked modern paths snaking through mixed woodland.
(2) It was opened on 17 June as part of celebrations to mark 100 years of independence from Russia, and €2.5m has been spent updating this 110 sq km area into a modern, accessible, waymarked park, with nature trails, mountain biking routes and pristine lakes and rivers.
(3) Continue in a straight line past the entrance to the visitor centre along the hard-surfaced path (waymarked NCN11).
(4) 2 Follow the waymarked route down towards the cliff edge.
(5) Take the number 5 bus from Ajaccio to the start of the waymarked path (in the car park) and it's a 40-minute round trip to the end of the Pointe de la Parata peninsula.
(6) With easy access on to the path and clear waymarking, it’s very easy to walk sections of the route independently, but several tour operators have packages, including British walking specialists Headwater ( headwater.com ) and Inntravel ( inntravel.co.uk ), and local outfits such as Ramblin’tejano ( ramblintejano.com ).
(7) The vote in the European parliament elections in May, the likely verdict of the Chilcot inquiry in the summer on the value of Britain's special relationship with America, and the referendum on Scottish independence in September will be three indispensable waymarks that will help chart the shape of modern Britain.
(8) The waymarked three-mile route begins at 10,900ft, from a trailhead eight miles south of Breckenridge.
(9) It has three waymarked walking routes, ranging from a simple 40 minute stroll (blue waymarkers) to more serious walks (green and red waymarkers) of up to 3 hours.
(10) Turn left, following the waymarked route back to the car park.
(11) Before reaching the road, take a waymarked path left which eventually leads you on to the road.
(12) Leave the coastal path and follow the waymarked path.
(13) Counsellor, Waymark Counselling Trust and Arcadia Counselling Service.
(14) As I sat staring out to sea I considered how tomorrow maybe I'd drive the 20km to the mountain village of Vero for the 1km waymarked Casteddu Loop, or head a little higher up to Bastelica (around 30km) for some real mountain scenery on a four- or five-hour circular route from the ski resort of Ese.
(15) • hackfall.org.uk Paul Kirkwood England Eaves Wood, Silverdale, Lancashire Follow the waymarked route from the National Trust car park along wooded paths, through dappled light and birdsong, into a land of Narnia.