(n.) The tissue which fills the cavities of most bones; the medulla. In the larger cavities it is commonly very fatty, but in the smaller cavities it is much less fatty, and red or reddish in color.
(n.) The essence; the best part.
(n.) One of a pair; a match; a companion; an intimate associate.
(v. t.) To fill with, or as with, marrow of fat; to glut.
Example Sentences:
(1) We have addressed the effect of late intensification with autologous bone marrow transplantation on SCLC through a randomized clinical trial.
(2) Our results indicate that increasing the delay for more than 8 days following irradiation and TCD syngeneic BMT leads to a rapid loss of the ability to achieve alloengraftment by non-TCD allogeneic bone marrow.
(3) Decreased MU stops additions of bone by modeling and increases removal of bone next to marrow by remodeling.
(4) Pokeweed mitogen-stimulated rat spleen cells were identified as a reliable source of rat burst-promoting activity (PBA), which permitted development of a reproducible assay for rat bone marrow erythroid burst-forming units (BFU-E).
(5) Survival was independent of the type of clinical presentation and protocol employed but was correlated with the stage (P less than 0.0005), symptoms (P less than 0.025), bulky disease (P less than 0.025) and bone marrow involvement (P less than 0.025).
(6) During the digestion of these radiolabeled bacteria, murine bone marrow macrophages produced low-molecular-weight substances that coeluted chromatographically with the radioactive cell wall marker.
(7) In later phases, mast cells appeared in the newly formed marrow in the external callus.
(8) Moreover, the data showed for the first time that DNA synthesis in the bone marrow and spleen and colon were markedly statistically significantly stimulated at specific times after treatment.
(9) It reduced serum AP levels, increased serum Ca levels, increased bone ash weight, epiphyseal and metaphyseal bone volume, with a concomitant reduction in epiphyseal and metaphyseal bone marrow volume.
(10) Some evidence has shown that platelet crossmatching is useful in multitransfused patients with hypoplastic bone marrows who are refractory to platelet therapy through alloimmunization.
(11) A previous trial into the safety and feasibility of using bone marrow stem cells to treat MS, led by Neil Scolding, a clinical neuroscientist at Bristol University, was deemed a success last year.
(12) A nonspecific reaction of the marrow against extramedullary lymphogranulomatosis closely resembling to the so-called tumor myeopathy has to be distinguished from the localized marrow changes due to the tumor itself.
(13) These agents have been well-tolerated and generally produce a high incidence of sustained improvements in neutrophil counts and marrow morphology, although hemoglobin and platelet counts have generally not been altered.
(14) After birth, it was in the liver and spleen up to 6 weeks af age, and thereafter it was present only in the bone marrow.
(15) This result indicates that the bone marrow is a very useful material for the detection of diazepam in skeletonized remains.
(16) In the first assay, we used a simple density separation technique to remove dense neutrophils (PMN) from suspensions of blood and of bone marrow cells prior to culture in semisolid agar.
(17) These results indicate that this population (approximately 0.1% of bone marrow) may contain the pluripotent hematopoietic stem cell.
(18) Four hours after injection radioactivity was identified in the spleen, liver, and bone marrow.
(19) A study was conducted to assess the suppression of segmental pancreatic allograft rejection by cyclosporine (CSA) alone in baboons and dogs, and subtotal marrow irradiation (TL1) alone and TL 1 in combination with CSA in baboons.
(20) Cell-free culture media conditioned by all but two of the seven types of monolayer studied inhibited haemoglobin synthesis by K562 cells; those conditioned by blood-monocyte-derived macrophages and two of 11 monolayers of bone-marrow-derived macrophages stimulated haemoglobin synthesis.
Medulla
Definition:
(n.) Marrow; pith; hence, essence.
(n.) The marrow of bones; the deep or inner portion of an organ or part; as, the medulla, or medullary substance, of the kidney; specifically, the medula oblongata.
(n.) A soft tissue, occupying the center of the stem or branch of a plant; pith.
Example Sentences:
(1) Furthermore, the local interneurons make extensive efferent synaptic connections with unidentified neurons in the terminal medulla.
(2) These findings suggest that AAT participates in the synthesis of transmitter aspartate in the medulla oblongata of the rat.
(3) These included the noradrenergic, TH- and DBH-immunoreactive cell groups of the pons and medulla.
(4) Size of both areas gradually decreased as the medulla filled with plasma cells, 7-30 days after injection.
(5) Obvious restitution of the thymic medulla was evident about 14 days after withdrawal of FK506.
(6) + inf., pons + medulla), rCBF increased toward the control level gradually, and it completely recovered 60 min after recirculation.
(7) It is well established that the renal medulla exerts a potent endocrine-like antihypertensive action.
(8) It was found that within the dorsal part of the well known pressor area there is a narrow strip, 2.5 mm lateral from the mid line, starting ventral to the inferior colliculus and ending in the medulla close to the floor of the IV ventricle, from which vasodilatation in skeletal muscles is selectively obtained.
(9) Urea decreased and valine increased in the TD medulla-pons.
(10) The sizes of adrenaline (A) and noradrenaline (N) cells in the adrenal medulla of nonoperated (NO), sham-operated (SPX), and pinealectomized (PX) male rats (n = 126) were investigated by quantitative light microscopy.
(11) Injection of horseradish peroxidase into the rostral ventrolateral medulla (RVLM) led to heavy retrograde and anterograde labeling in the region of the hypothalamus that yielded the CRDR when stimulated electrically.
(12) The object of these studies was to investigate whether destruction of the renal medulla in normal rats would alter vascular capacitance.
(13) The presence in lamprey kidney of a loop which is similar to Henle's loop in mammals and birds indicates that the development of the system of osmotic concentration conditioned by the formation in the kidney of the medulla and from a sharp increase in renal arterial blood supply.
(14) Our results suggest that multiple receptors and signal transduction pathways are involved in the regulation of the tyrosine hydroxylase gene in the rat adrenal medulla.
(15) In hypertensive rats (SHR) the density of alpha 2-adrenoceptors was reduced in the cerebral cortex, hypothalamus and medulla oblongata (20-27%), as was the dose-pupillary response curve for clonidine (1.8-fold).
(16) An antihypertensive function in systemic blood pressure control has been attributed to the renal medulla.
(17) 1 After the injection of labelled procaine and lidocaine in mice, the location and concentration of radioactivity was demonstrated by autoradiographical methods.2 An accumulation in some endocrine cells such as the pancreatic islets, the hypophysis, the adrenal medulla and certain cells of the thyroid (probably representing the calcitonin-producing parafollicular cells) was shown.3 After the injection of [(14)C]-procaine in chicks, an accumulation of radioactivity was observed in the ultimobranchial gland (which produces calcitonin in birds), but not in the thyroid.4 Radioactivity was also shown to be strongly concentrated in structures containing melanin, such as the pigment of the eye, skin and hair and in some organs involved in the metabolism and excretion of these drugs.
(18) Histologically, increased amounts of fibrotic tissue in the medulla and the cortex were found together with tubular atrophy.
(19) Two well-defined zones are observed both in the medulla and in the cortex.
(20) One infant had a unilateral infarction in the medulla and another showed extensive gliosis in the brainstem tegmentum along with a large infarction in the region of the anterior cerebral artery.