(n.) The tissue which fills the cavities of most bones; the medulla. In the larger cavities it is commonly very fatty, but in the smaller cavities it is much less fatty, and red or reddish in color.
(n.) The essence; the best part.
(n.) One of a pair; a match; a companion; an intimate associate.
(v. t.) To fill with, or as with, marrow of fat; to glut.
Example Sentences:
(1) We have addressed the effect of late intensification with autologous bone marrow transplantation on SCLC through a randomized clinical trial.
(2) Our results indicate that increasing the delay for more than 8 days following irradiation and TCD syngeneic BMT leads to a rapid loss of the ability to achieve alloengraftment by non-TCD allogeneic bone marrow.
(3) Decreased MU stops additions of bone by modeling and increases removal of bone next to marrow by remodeling.
(4) Pokeweed mitogen-stimulated rat spleen cells were identified as a reliable source of rat burst-promoting activity (PBA), which permitted development of a reproducible assay for rat bone marrow erythroid burst-forming units (BFU-E).
(5) Survival was independent of the type of clinical presentation and protocol employed but was correlated with the stage (P less than 0.0005), symptoms (P less than 0.025), bulky disease (P less than 0.025) and bone marrow involvement (P less than 0.025).
(6) During the digestion of these radiolabeled bacteria, murine bone marrow macrophages produced low-molecular-weight substances that coeluted chromatographically with the radioactive cell wall marker.
(7) In later phases, mast cells appeared in the newly formed marrow in the external callus.
(8) Moreover, the data showed for the first time that DNA synthesis in the bone marrow and spleen and colon were markedly statistically significantly stimulated at specific times after treatment.
(9) It reduced serum AP levels, increased serum Ca levels, increased bone ash weight, epiphyseal and metaphyseal bone volume, with a concomitant reduction in epiphyseal and metaphyseal bone marrow volume.
(10) Some evidence has shown that platelet crossmatching is useful in multitransfused patients with hypoplastic bone marrows who are refractory to platelet therapy through alloimmunization.
(11) A previous trial into the safety and feasibility of using bone marrow stem cells to treat MS, led by Neil Scolding, a clinical neuroscientist at Bristol University, was deemed a success last year.
(12) A nonspecific reaction of the marrow against extramedullary lymphogranulomatosis closely resembling to the so-called tumor myeopathy has to be distinguished from the localized marrow changes due to the tumor itself.
(13) These agents have been well-tolerated and generally produce a high incidence of sustained improvements in neutrophil counts and marrow morphology, although hemoglobin and platelet counts have generally not been altered.
(14) After birth, it was in the liver and spleen up to 6 weeks af age, and thereafter it was present only in the bone marrow.
(15) This result indicates that the bone marrow is a very useful material for the detection of diazepam in skeletonized remains.
(16) In the first assay, we used a simple density separation technique to remove dense neutrophils (PMN) from suspensions of blood and of bone marrow cells prior to culture in semisolid agar.
(17) These results indicate that this population (approximately 0.1% of bone marrow) may contain the pluripotent hematopoietic stem cell.
(18) Four hours after injection radioactivity was identified in the spleen, liver, and bone marrow.
(19) A study was conducted to assess the suppression of segmental pancreatic allograft rejection by cyclosporine (CSA) alone in baboons and dogs, and subtotal marrow irradiation (TL1) alone and TL 1 in combination with CSA in baboons.
(20) Cell-free culture media conditioned by all but two of the seven types of monolayer studied inhibited haemoglobin synthesis by K562 cells; those conditioned by blood-monocyte-derived macrophages and two of 11 monolayers of bone-marrow-derived macrophages stimulated haemoglobin synthesis.
Substance
Definition:
(n.) That which underlies all outward manifestations; substratum; the permanent subject or cause of phenomena, whether material or spiritual; that in which properties inhere; that which is real, in distinction from that which is apparent; the abiding part of any existence, in distinction from any accident; that which constitutes anything what it is; real or existing essence.
(n.) The most important element in any existence; the characteristic and essential components of anything; the main part; essential import; purport.
(n.) Body; matter; material of which a thing is made; hence, substantiality; solidity; firmness; as, the substance of which a garment is made; some textile fabrics have little substance.
(n.) Material possessions; estate; property; resources.
(n.) Same as Hypostasis, 2.
(v. t.) To furnish or endow with substance; to supply property to; to make rich.
Example Sentences:
(1) No differences between the two substances were observed with respect to side effects and general tolerability.
(2) Modulation of the voltage-gated K+ conductance in T-lymphocytes by substance P was examined.
(3) During the digestion of these radiolabeled bacteria, murine bone marrow macrophages produced low-molecular-weight substances that coeluted chromatographically with the radioactive cell wall marker.
(4) Intracellular localization of the labeled substance in the tumor tissue was examined autohistoradiographically.
(5) Substances with a leaving group at the C-3 position form unsaturated conjugated cyclic adducts and are mutagenic only in the His D3052 frameshift strains with an intact excision repair system (no urvA mutation).
(6) A substance with a chromatographic mobility of Rf = 0.8 on TLC plates having an intact phosphorylcholine head group was also formed but has not yet been identified.
(7) Serum pepsinogen 1, serum gastrin, ABO blood groups, secretor status of ABH blood group substances and behavioral factors were studied in 15 patients with duodenal ulcer and 61 their relatives affected and unaffected to duodenal ulcer.
(8) Agarose-albumin beads may be useful for removing protein-bound substances from the blood of patients with liver failure, intoxication with protein-bound drugs, or specific metabolic deficits.
(9) Urine tests in six patients with other kidney diseases and with uraemia and in seven healthy persons did not show this substance.
(10) Substance P, a potent vasodilating peptide, seems to be released from trigeminal nerve endings in response to nervous stimulation and is involved in the transmission of painful stimuli within the periphery.
(11) Regulators concerned about physician behavior and confronted by demands of nonphysicians to prescribe controlled substances may find EDT a good solution.
(12) These results are discussed in the light of the mode of action of the substances used.
(13) Most cis AB sera have anti-B activity, essentially at 4 degrees C. In saliva A and H substances are found in normal amounts but B substance is only evidenced by inhibition of autologous cells agglutination.
(14) We have investigated some of the factors which affect the retention times of these substances in reversed-phase HPLC on columns of 5-micron octadecylsilyl silica.
(15) The data indicate that adult neurons with an intrinsic ability to regenerate axons can respond to substances with neurotrophic or neurite-promoting activities in tissue cultures.
(16) The authors describe the role played by these substances in the pathogenesis of inflammations, their importance in the regulation of intraocular pressure and in the development of cystoid macular oedema.
(17) They were more irregularly curved and consisted of various substances.
(18) We examined 10 life areas clustered around the general categories of "substance use," "social functioning," and "emotional and interpersonal functioning."
(19) In certain cases, the effects of these substances are enhanced, in others, they are inhibited by compounds that were isolated from natural sources or prepared by chemical synthesis.
(20) The following possible explanations were discussed: a) the tested psychotropic drugs block prostaglandin receptors in the stomach; b) the test substances react with prostaglandin in the nutritive solution; c) the substances stimulate metabolic processes in the stomach wall that break down prostaglandin.