What's the difference between median and mediator?

Median


Definition:

  • (a.) Being in the middle; running through the middle; as, a median groove.
  • (a.) Situated in the middle; lying in a plane dividing a bilateral animal into right and left halves; -- said of unpaired organs and parts; as, median coverts.
  • (n.) A median line or point.

Example Sentences:

  • (1) The mean and median values in the nondiabetic group are higher than in previously published reports.
  • (2) However, time in greater than 21% oxygen was significantly longer in infants less than 1000 g (median 30 days, 8.5 days in patients greater than 1000 g, p less than 0.01).
  • (3) Standard nerve conduction techniques using constant measured distances were applied to evaluate the median, ulnar and radial nerves.
  • (4) Only candidacidal activity was enhanced in FCA-elicited peritoneal macrophages (median C. albicans killed 28% versus 16% for resident peritoneal macrophages, p less than 0.01).
  • (5) Local application of 8-OH-DPAT (0-5 micrograms) into the median raphe nucleus, facilitated male rat sexual behavior, as evidenced by a decrease in number of intromissions preceding ejaculation and in time to ejaculation.
  • (6) Median effect analysis was applied for the evaluation of in vitro effect by the growth inhibition, and the in vivo effect by comparison of the increase of life span (ILS) in a combined group with the sum of ILS's in 2 single agent groups.
  • (7) Median time for ventilatory support was 90 minutes after transfer to the area.
  • (8) As of November, 1988 after a median observation period of 34 months, 174 of the 256 patients (68%) were alive, 11 (4%) dead and 71 (28%) lost to follow-up.
  • (9) Unilateral VNAB lesions induced similar alterations but these were restricted to the ipsilateral PVN and median eminence.
  • (10) SPRs were elicited either by stimulating the reticular formation or the distal end of the median nerve.
  • (11) The criteria for sero-positivity was determined from the median antibody concentration in a group of 368 non-endoscoped control patients.
  • (12) With a median follow-up of 6 years, 32 (20%) of 156 patients who achieved complete remission have relapsed.
  • (13) The median survival after radiotherapy is 17.4 months.
  • (14) But the median survival time was 30.7 months in Arm A and 24.5 months in Arm B, and significantly longer in Arm A until 10 months.
  • (15) The median functional protein S of these patients was 71% (40-101%).
  • (16) Using the MTT assay and analyzing the data using the median-effect principle, we showed that synergistic cytotoxic interactions exist between CDDP and VM in their liposomal form.
  • (17) At concentrations below the respective median for each variable, odds ratios of between 1.42 and 1.67 were calculated whereas at concentrations above the respective medians the odds ratios ranged from 4.50 to 6.33 (P less than 0.001).
  • (18) The median blood levels were lower in hyperacidic subjects and higher in hypoacidic patients; the urinary excretion of the digitalis compound showed no essential differences.
  • (19) Irradiation of the skin overlying the median nerve at the wrist in humans with a low power (1 mW; 632.5 nm) helium-neon laser produced a somatosensory evoked potential obtained at Erb's point.
  • (20) Most of the bilateral lung lesions were removed through a median sternotomy so as to avoid staged bilateral thoracotomy.

Mediator


Definition:

  • (n.) One who mediates; especially, one who interposes between parties at variance for the purpose of reconciling them; hence, an intercessor.

Example Sentences:

  • (1) Stimulation of human leukocytes with various chemical mediators such as TPA, f-Met-Leu-Phe, LTB4, etc.
  • (2) Fibulin is a potential mediator of interactions between adhesion receptors and the cytoskeleton.
  • (3) Patients with papillary carcinoma with a good cell-mediated immune response occurred with much lower infiltration of the tumor boundary with lymphocyte whereas the follicular carcinoma less cell-mediated immunity was associated with dense lymphocytic infiltration, suggesting the biological relevance of lymphocytic infiltration may be different for the two histologic variants.
  • (4) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
  • (5) We have investigated the effect of methimazole (MMI) on cell-mediated immunity and ascertained the mechanisms of immunosuppression produced by the drug.
  • (6) We determined whether serological investigations can assist to distinguish between chronic idiopathic autoimmune thrombocytopenia (cAITP) and immune-mediated thrombocytopenia in patients at risk to develop systemic lupus erythematosus (SLE); 82 patients were seen in this institution for the evaluation of immune thrombocytopenia.
  • (7) IgE-mediated acute systemic reactions to penicillin continue to be an important clinical problem.
  • (8) This induction is sensitive to actinomycin D but not to protein synthesis inhibitor puromycin, indicating an effect of estradiol at the transcriptional level, possibly mediated by the estrogen receptor.
  • (9) We sought additional evidence for an inverse relationship between functional CTL-target cell affinity on the one hand, and susceptibility of the CTL-mediated killing to inhibition by alpha LFA-1 and alpha Lyt-2,3 monoclonal antibodies on the other hand.
  • (10) Mannose receptor mediated uptake by the reticuloendothelial system has been suggested as an explanation for the rapid removal of ricin A chain antibody conjugates from the circulation after their administration.
  • (11) However, direct measurements of mediator release should be carried out to reach a firm conclusion.
  • (12) In addition to their involvement in thrombosis, activated platelets release growth factors, most notably a platelet-derived growth factor (PDGF) which may be the principal mediator of smooth muscle cell migration from the media into the intima and of smooth muscle cell proliferation in the intima as well as of vasoconstriction.
  • (13) Glutathion peroxidase and p-phenylenediamide-mediated peroxidase (PPD-peroxidase) were normal in leucocytes of 1 HPS patient.
  • (14) But MH162 was more effective than MRK16 in lymphocyte-mediated lysis of the MDR cells.
  • (15) Thus, human bronchial epithelial cells can express the IL-8 gene, with expression in response to the inflammatory mediator TNF regulated mainly at the transcriptional level, and with elements within the 5'-flanking region of the gene that are directly or indirectly modulated by the TNF signal.
  • (16) Tumour necrosis factor (TNF), a polypeptide produced by mononuclear phagocytes, has been implicated as an important mediator of inflammatory processes and of clinical manifestations in acute infectious diseases.
  • (17) From these results, it was suggested that the inhibitory effect of Cd on in vitro calcification of MC3T3-E1 cells may be due to both a depression of cell-mediated calcification and a decrease in physiochemical mineral deposition.
  • (18) injection of various inflammatory mediators, the vasopressor effect of i.a.
  • (19) It is concluded that fibroblast replication is an important mechanism leading to the pathologic fibrosis seen in graft versus host disease and, by analogy, probably other types of immunologically mediated fibrosis.
  • (20) The authors followed up the occurrence of inflammation-mediated osteopenia (IMO) in young and adult rats weighing 50 g and 150 g, respectively.