(a.) Being between the two extremes; middle; interposed; intervening; intermediate.
(a.) Acting by means, or by an intervening cause or instrument; not direct or immediate; acting or suffering through an intervening agent or condition.
(a.) Gained or effected by a medium or condition.
(a.) To be in the middle, or between two; to intervene.
(a.) To interpose between parties, as the equal friend of each, esp. for the purpose of effecting a reconciliation or agreement; as, to mediate between nations.
(v. t.) To effect by mediation or interposition; to bring about as a mediator, instrument, or means; as, to mediate a peace.
(v. t.) To divide into two equal parts.
Example Sentences:
(1) Stimulation of human leukocytes with various chemical mediators such as TPA, f-Met-Leu-Phe, LTB4, etc.
(2) Fibulin is a potential mediator of interactions between adhesion receptors and the cytoskeleton.
(3) Patients with papillary carcinoma with a good cell-mediated immune response occurred with much lower infiltration of the tumor boundary with lymphocyte whereas the follicular carcinoma less cell-mediated immunity was associated with dense lymphocytic infiltration, suggesting the biological relevance of lymphocytic infiltration may be different for the two histologic variants.
(4) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(5) We have investigated the effect of methimazole (MMI) on cell-mediated immunity and ascertained the mechanisms of immunosuppression produced by the drug.
(6) We determined whether serological investigations can assist to distinguish between chronic idiopathic autoimmune thrombocytopenia (cAITP) and immune-mediated thrombocytopenia in patients at risk to develop systemic lupus erythematosus (SLE); 82 patients were seen in this institution for the evaluation of immune thrombocytopenia.
(7) IgE-mediated acute systemic reactions to penicillin continue to be an important clinical problem.
(8) This induction is sensitive to actinomycin D but not to protein synthesis inhibitor puromycin, indicating an effect of estradiol at the transcriptional level, possibly mediated by the estrogen receptor.
(9) We sought additional evidence for an inverse relationship between functional CTL-target cell affinity on the one hand, and susceptibility of the CTL-mediated killing to inhibition by alpha LFA-1 and alpha Lyt-2,3 monoclonal antibodies on the other hand.
(10) Mannose receptor mediated uptake by the reticuloendothelial system has been suggested as an explanation for the rapid removal of ricin A chain antibody conjugates from the circulation after their administration.
(11) However, direct measurements of mediator release should be carried out to reach a firm conclusion.
(12) In addition to their involvement in thrombosis, activated platelets release growth factors, most notably a platelet-derived growth factor (PDGF) which may be the principal mediator of smooth muscle cell migration from the media into the intima and of smooth muscle cell proliferation in the intima as well as of vasoconstriction.
(13) Glutathion peroxidase and p-phenylenediamide-mediated peroxidase (PPD-peroxidase) were normal in leucocytes of 1 HPS patient.
(14) But MH162 was more effective than MRK16 in lymphocyte-mediated lysis of the MDR cells.
(15) Thus, human bronchial epithelial cells can express the IL-8 gene, with expression in response to the inflammatory mediator TNF regulated mainly at the transcriptional level, and with elements within the 5'-flanking region of the gene that are directly or indirectly modulated by the TNF signal.
(16) Tumour necrosis factor (TNF), a polypeptide produced by mononuclear phagocytes, has been implicated as an important mediator of inflammatory processes and of clinical manifestations in acute infectious diseases.
(17) From these results, it was suggested that the inhibitory effect of Cd on in vitro calcification of MC3T3-E1 cells may be due to both a depression of cell-mediated calcification and a decrease in physiochemical mineral deposition.
(18) injection of various inflammatory mediators, the vasopressor effect of i.a.
(19) It is concluded that fibroblast replication is an important mechanism leading to the pathologic fibrosis seen in graft versus host disease and, by analogy, probably other types of immunologically mediated fibrosis.
(20) The authors followed up the occurrence of inflammation-mediated osteopenia (IMO) in young and adult rats weighing 50 g and 150 g, respectively.
Meditate
Definition:
(v. i.) To keep the mind in a state of contemplation; to dwell on anything in thought; to think seriously; to muse; to cogitate; to reflect.
(v. t.) To contemplate; to keep the mind fixed upon; to study.
(v. t.) To purpose; to intend; to design; to plan by revolving in the mind; as, to meditate a war.
Example Sentences:
(1) Since he was created, he has appeared at several robotic fairs across China, but spends most of his time in deep meditation on an office shelf in Longquan.
(2) Marie Johansson, clinical lead at Oxford University's mindfulness centre , stressed the need for proper training of at least a year until health professionals can teach meditation, partly because on rare occasions it can throw up "extremely distressing experiences".
(3) A total of 48 subjects participated in a relaxation experiment to determine whether frontalis muscle EMG biofeedback, Transcendental Meditation, and meditation (Benson technique) produced decreased muscle tension and concomitant changes in locus of control.
(4) No clear evidence was thus obtained that any of the stress, or stress-related, hormones were suppressed during or after meditation in the particular setting examined.
(5) She says that, while she stayed away from the more difficult ramifications of that upbringing, she nevertheless plunged right into the "hot quicksand" of the Arab-Israeli conflict, right down into the Biblical roots of Jewish-Muslim conflict in the story of Abraham, Hagar, Isaac and Ishmael (which she meditates upon in the opera's Hagar chorus), and into the vortex of questions about Israel's right to exist and what motivates terrorists.
(6) The highly significant increase of 5-HIAA (5-hydroxyindole-3-acetic acid) in Transcendental Meditation technique suggests systemic serotonin as "rest and fulfillment hormone" of deactivation-relaxation.
(7) Meditation and aerobic activity were associated with a perception of increased ability to cope and a generally positive feeling about the value of exercise and meditation in their lives.
(8) In the meditation hall, daddy longlegs dropped from the ceiling, feeding my anxiety.
(9) Ratings from 84 students of selected attitudes before a brief introduction to a method of meditation and responses afterward correlated moderately, suggesting those favoring personal growth will favor meditation.
(10) The data indicated that certain effects attributed to the practice of Transcendental Meditation (such as increased alertness and maintenance of attention, greater consistency and less anxiety) are not manifested in terms of learning and performance of a novel perceptual-motor skill.
(11) Serum dehydroepiandrosterone sulfate (DHEA-S) levels were measured in 270 men and 153 women who were experienced practitioners of the Transcendental Meditation (TM) and TM-Sidhi programs, mental techniques practiced twice daily, sitting quietly with the eyes closed.
(12) To assess the effects of exercise and meditation on alcohol consumption in social drinkers, 60 male students, between the ages of 21 and 30, all classified as heavy social drinkers, were randomly assigned to one of three conditions: exercise (running), meditation, and a no-treatment control group.
(13) Contact was made with a ‘mystical-religious’ group that used the gas to accelerate arriving at their transcendental-meditative state of choice.” It increased in popularity with the rise of festival culture – it’s been a mainstay of Glastonbury’s stone circle and squat parties in Bristol and south London for at least a decade – but the equipment needed to dispense it remained relatively expensive.
(14) Famously ascetic, teetotal and vegetarian, he meditates, practises yoga and shuns the trappings of office.
(15) Two of the three meditational procedure subjects also showed an increase in subjective tension as measured by the anxiety lever.
(16) The solution would appear (sometimes the novel felt like a vast crossword puzzle) through a combination of experiment, meditation and lateral thought: I had to step firmly away from the French and face a contrary direction – another track entirely.
(17) The chapel is identified by the school as a Christian church but also hosts Hindu services and has been used for Buddhist meditations.
(18) These observations indicate that neither stress nor operation of other usual homeostatic control mechanisms are responsible for elevated for AVP in the meditators.
(19) At the end of 1971 Drake wrote some new songs in Tanworth, but they constituted a clean break from the second- and third-person meditations of the previous two albums.
(20) The therapy would appear to be improved by the inclusion of mental relaxation, concentration, meditation, and mind-blanking exercises for mental control.