(a.) Being between the two extremes; middle; interposed; intervening; intermediate.
(a.) Acting by means, or by an intervening cause or instrument; not direct or immediate; acting or suffering through an intervening agent or condition.
(a.) Gained or effected by a medium or condition.
(a.) To be in the middle, or between two; to intervene.
(a.) To interpose between parties, as the equal friend of each, esp. for the purpose of effecting a reconciliation or agreement; as, to mediate between nations.
(v. t.) To effect by mediation or interposition; to bring about as a mediator, instrument, or means; as, to mediate a peace.
(v. t.) To divide into two equal parts.
Example Sentences:
(1) Stimulation of human leukocytes with various chemical mediators such as TPA, f-Met-Leu-Phe, LTB4, etc.
(2) Fibulin is a potential mediator of interactions between adhesion receptors and the cytoskeleton.
(3) Patients with papillary carcinoma with a good cell-mediated immune response occurred with much lower infiltration of the tumor boundary with lymphocyte whereas the follicular carcinoma less cell-mediated immunity was associated with dense lymphocytic infiltration, suggesting the biological relevance of lymphocytic infiltration may be different for the two histologic variants.
(4) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(5) We have investigated the effect of methimazole (MMI) on cell-mediated immunity and ascertained the mechanisms of immunosuppression produced by the drug.
(6) We determined whether serological investigations can assist to distinguish between chronic idiopathic autoimmune thrombocytopenia (cAITP) and immune-mediated thrombocytopenia in patients at risk to develop systemic lupus erythematosus (SLE); 82 patients were seen in this institution for the evaluation of immune thrombocytopenia.
(7) IgE-mediated acute systemic reactions to penicillin continue to be an important clinical problem.
(8) This induction is sensitive to actinomycin D but not to protein synthesis inhibitor puromycin, indicating an effect of estradiol at the transcriptional level, possibly mediated by the estrogen receptor.
(9) We sought additional evidence for an inverse relationship between functional CTL-target cell affinity on the one hand, and susceptibility of the CTL-mediated killing to inhibition by alpha LFA-1 and alpha Lyt-2,3 monoclonal antibodies on the other hand.
(10) Mannose receptor mediated uptake by the reticuloendothelial system has been suggested as an explanation for the rapid removal of ricin A chain antibody conjugates from the circulation after their administration.
(11) However, direct measurements of mediator release should be carried out to reach a firm conclusion.
(12) In addition to their involvement in thrombosis, activated platelets release growth factors, most notably a platelet-derived growth factor (PDGF) which may be the principal mediator of smooth muscle cell migration from the media into the intima and of smooth muscle cell proliferation in the intima as well as of vasoconstriction.
(13) Glutathion peroxidase and p-phenylenediamide-mediated peroxidase (PPD-peroxidase) were normal in leucocytes of 1 HPS patient.
(14) But MH162 was more effective than MRK16 in lymphocyte-mediated lysis of the MDR cells.
(15) Thus, human bronchial epithelial cells can express the IL-8 gene, with expression in response to the inflammatory mediator TNF regulated mainly at the transcriptional level, and with elements within the 5'-flanking region of the gene that are directly or indirectly modulated by the TNF signal.
(16) Tumour necrosis factor (TNF), a polypeptide produced by mononuclear phagocytes, has been implicated as an important mediator of inflammatory processes and of clinical manifestations in acute infectious diseases.
(17) From these results, it was suggested that the inhibitory effect of Cd on in vitro calcification of MC3T3-E1 cells may be due to both a depression of cell-mediated calcification and a decrease in physiochemical mineral deposition.
(18) injection of various inflammatory mediators, the vasopressor effect of i.a.
(19) It is concluded that fibroblast replication is an important mechanism leading to the pathologic fibrosis seen in graft versus host disease and, by analogy, probably other types of immunologically mediated fibrosis.
(20) The authors followed up the occurrence of inflammation-mediated osteopenia (IMO) in young and adult rats weighing 50 g and 150 g, respectively.
Parties
Definition:
(pl. ) of Party
Example Sentences:
(1) Until his return to Brazil in 1985, Niemeyer worked in Israel, France and north Africa, designing among other buildings the University of Haifa on Mount Carmel; the campus of Constantine University in Algeria (now known as Mentouri University); the offices of the French Communist party and their newspaper l'Humanité in Paris; and the ministry of external relations and the cathedral in Brasilia.
(2) Another interested party, the University of Miami, had been in talks with the Beckham group over the potential for a shared stadium project.
(3) However, as the same task confronts the Lib Dems, do we not now have a priceless opportunity to bring the two parties together to undertake a fundamental rethink of the way social democratic principles and policies can be made relevant to modern society.
(4) A spokesman for the Greens said that the party was “disappointed” with the decision and would be making representations to both the BBC and BBC Trust .
(5) Brown's model, which goes far further than those from any other senior Labour figure, and the modest new income tax powers for Holyrood devised when he was prime minister, edge the party much closer to the quasi-federal plans championed by the Liberal Democrats.
(6) To a supporter at the last election like me – someone who spoke alongside Nick Clegg at the curtain-raiser event for the party conference during the height of Labour's onslaught on civil liberties, and was assured privately by two leaders that the party was onside about civil liberties – this breach of trust and denial of principle is astonishing.
(7) After friends heard that he was on them, Brumfield started observing something strange: “If we had people over to the Super Bowl or a holiday season party, I’d notice that my medicines would come up short, no matter how good friends they were.” Twice people broke into his house to get to the drugs.
(8) Finally, before the advent of the third-party payment, operations were avoided because of the financial burden.
(9) On 17 December Clegg will set out his own script for the year ahead, testing the idea that coalition governments can function even as the two parties clearly show their separate colours.
(10) A “significant” number of resignations from the party had come in on Tuesday and Giles queried whether the CLP still had the 500 members it needs to remain registered.
(11) What’s needed is manifesto commitments from all the main political parties to improve the help single homeless people are legally entitled to.
(12) Cameron, who faces intense political pressure from the UK Independence party in the runup to the 2014 European parliamentary elections, believes voters will need to be consulted if the EU agrees a major treaty revision in the next few years.
(13) "I saw my role, and continue to do so, as doing everything I can to accelerate the Lib Dems' journey from a party of protest to a party of government," he said.
(14) Canvassing previous Labour voters who were pro-independence or still undecided during the referendum, McGarry hears complaints that the party is no longer socialist and should not have sided with the Tories at the referendum.
(15) The appointment of the mayor of London's brother, who formally becomes a Cabinet Office minister, is one of a series of moves designed to strengthen the political operation in Downing Street and to patch up the prime minister's frayed links with the Conservative party.
(16) Sharif's family insist that he still runs the party from jail.
(17) All 17 candidates are going to be participating in debate night and I think that’s a wonderful opportunity Reince Priebus Republican party officials have defended the decision to limit participation, pointing out that the chasing pack will get a chance to debate separately before the main event.
(18) On Monday, the day after a party congress officially cementing Putin's candidacy in the 4 March presidential election, the top stories on Inosmi concerned modernisation, the eurozone crisis and Iran.
(19) Any party or witness is entitled to use Welsh in any magistrates court in Wales without prior notice.
(20) The Nazi party’s office of racial purity claimed that the Jewish character was essentially drug-dependent.