(a.) Being between the two extremes; middle; interposed; intervening; intermediate.
(a.) Acting by means, or by an intervening cause or instrument; not direct or immediate; acting or suffering through an intervening agent or condition.
(a.) Gained or effected by a medium or condition.
(a.) To be in the middle, or between two; to intervene.
(a.) To interpose between parties, as the equal friend of each, esp. for the purpose of effecting a reconciliation or agreement; as, to mediate between nations.
(v. t.) To effect by mediation or interposition; to bring about as a mediator, instrument, or means; as, to mediate a peace.
(v. t.) To divide into two equal parts.
Example Sentences:
(1) Stimulation of human leukocytes with various chemical mediators such as TPA, f-Met-Leu-Phe, LTB4, etc.
(2) Fibulin is a potential mediator of interactions between adhesion receptors and the cytoskeleton.
(3) Patients with papillary carcinoma with a good cell-mediated immune response occurred with much lower infiltration of the tumor boundary with lymphocyte whereas the follicular carcinoma less cell-mediated immunity was associated with dense lymphocytic infiltration, suggesting the biological relevance of lymphocytic infiltration may be different for the two histologic variants.
(4) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(5) We have investigated the effect of methimazole (MMI) on cell-mediated immunity and ascertained the mechanisms of immunosuppression produced by the drug.
(6) We determined whether serological investigations can assist to distinguish between chronic idiopathic autoimmune thrombocytopenia (cAITP) and immune-mediated thrombocytopenia in patients at risk to develop systemic lupus erythematosus (SLE); 82 patients were seen in this institution for the evaluation of immune thrombocytopenia.
(7) IgE-mediated acute systemic reactions to penicillin continue to be an important clinical problem.
(8) This induction is sensitive to actinomycin D but not to protein synthesis inhibitor puromycin, indicating an effect of estradiol at the transcriptional level, possibly mediated by the estrogen receptor.
(9) We sought additional evidence for an inverse relationship between functional CTL-target cell affinity on the one hand, and susceptibility of the CTL-mediated killing to inhibition by alpha LFA-1 and alpha Lyt-2,3 monoclonal antibodies on the other hand.
(10) Mannose receptor mediated uptake by the reticuloendothelial system has been suggested as an explanation for the rapid removal of ricin A chain antibody conjugates from the circulation after their administration.
(11) However, direct measurements of mediator release should be carried out to reach a firm conclusion.
(12) In addition to their involvement in thrombosis, activated platelets release growth factors, most notably a platelet-derived growth factor (PDGF) which may be the principal mediator of smooth muscle cell migration from the media into the intima and of smooth muscle cell proliferation in the intima as well as of vasoconstriction.
(13) Glutathion peroxidase and p-phenylenediamide-mediated peroxidase (PPD-peroxidase) were normal in leucocytes of 1 HPS patient.
(14) But MH162 was more effective than MRK16 in lymphocyte-mediated lysis of the MDR cells.
(15) Thus, human bronchial epithelial cells can express the IL-8 gene, with expression in response to the inflammatory mediator TNF regulated mainly at the transcriptional level, and with elements within the 5'-flanking region of the gene that are directly or indirectly modulated by the TNF signal.
(16) Tumour necrosis factor (TNF), a polypeptide produced by mononuclear phagocytes, has been implicated as an important mediator of inflammatory processes and of clinical manifestations in acute infectious diseases.
(17) From these results, it was suggested that the inhibitory effect of Cd on in vitro calcification of MC3T3-E1 cells may be due to both a depression of cell-mediated calcification and a decrease in physiochemical mineral deposition.
(18) injection of various inflammatory mediators, the vasopressor effect of i.a.
(19) It is concluded that fibroblast replication is an important mechanism leading to the pathologic fibrosis seen in graft versus host disease and, by analogy, probably other types of immunologically mediated fibrosis.
(20) The authors followed up the occurrence of inflammation-mediated osteopenia (IMO) in young and adult rats weighing 50 g and 150 g, respectively.
Wrapper
Definition:
(n.) One who, or that which, wraps.
(n.) That in which anything is wrapped, or inclosed; envelope; covering.
(n.) Specifically, a loose outer garment; an article of dress intended to be wrapped round the person; as, a morning wrapper; a gentleman's wrapper.
Example Sentences:
(1) Lauren Eyles, MCS Beachwatch officer, said: "Despite last summer being seen as a washout by many with heavy rain in many places, it appears those people that did visit our beaches left behind a lot of personal litter – sweet wrappers, ice cream wrappers and plastic drinks bottles failed to find their way into rubbish bins and ended up being dropped and left behind.
(2) It’s just one in a long line of cowardly and slimy moves by Ryan, who is really just Trump in a more aesthetically appealing wrapper.
(3) A foreign body consisting of a piece of a celophane candy wrapper was found by surgery.
(4) So there would be no more bundling up dodgy mortgages and flogging them in fancy wrappers.
(5) Subjects were presented with Hershey's kisses wrapped in either transparent (visible) or non-transparent (non-visible) wrappers while performing a sham test; the number of chocolates consumed was the dependent measure.
(6) Water bottles, sweet wrappers, sanitary towels and footprints are telltale signs, as is a bivouac made from bushes to shelter the migrants from the heat of the day so they can continue their journey at night.
(7) Analysis of unused wrappers showed 76-88% of the total DBP and DEHP to be present on the foil (outer) surface as a component of the protective coating (washcoat).
(8) Several providers, including Aldermore, Nationwide, Newcastle building society and NatWest, however, operate their Isas inside a wrapper, which means you can transfer all your money to them and distribute it between the help-to-buy Isa and their other cash Isas.
(9) A noble idea – offering free sports equipment to schools in return for collecting chocolate wrappers – backfired disastrously when it emerged that a child eating enough chocolate to "earn" a free basketball would have to play the game continuously for four days and nights to burn off the calories they had consumed to get it.
(10) In every grocery store, Kumamon smiles from every punnet of strawberries and honeydew melon wrapper.
(11) Vegetarian haggis gyoza dumplings You can make your own wrappers, but it's much easier to buy them frozen at Japanese or Oriental shops.
(12) Back in Whitstable the kite-surfers were having a ball, leaping high above the sea in the strong gusts of wind, their acrobatics watched forlornly by the seagulls, waiting to scavenge discarded chip wrappers that would never come.
(13) Exposed meat wrappers showed a higher prevalence of cough, phlegm, hay fever, and asthma than did the control group.
(14) The village is a smattering of fishing shacks frequented by stray dogs and chickens; the sand is littered with sweet wrappers, water bottles, flip-flops and polystyrene food containers; the sea is cloudy from the dredging.
(15) Serves 6 For the wrappers 200g plain flour ¼ tsp baking powder A good pinch of salt 100ml water 3 tbsp cornflour, for dusting For the filling 250g chicken or pork mince 1 red onion, finely chopped 2 garlic cloves, chopped 5cm-piece of fresh ginger, chopped 5 green chillies, chopped 2 spring onions, chopped 5g black peppercorns, crushed 2 tbsp chopped fresh coriander 1 tsp cumin powder, roasted ½ tsp garam masala powder 75g butter 1¼ tsp salt Juice of one lemon 1 To make the momo wrappers, sift the flour and baking powder on to a work surface.
(16) Sitting in the shelter with her son, Luis, a half-eaten cookie in a wrapper on the table in front of him, Maldonado said that they decided to leave when a gang tried to recruit the 17-year-old.
(17) Or, if it’s been a stressful one, a pile of KitKat wrappers!
(18) There is also some quite magnificent socialising, including being part of the inner circle at the Factory, and fabled New York nightclub Studio 54 (Jones was a close confidante of Warhol, and drops celebrity names as nonchalantly as sweet wrappers).
(19) Connolly says older people should be wary of taking money out of cash Isas to put into the bonds, as they would lose the tax-free wrapper for the sake of a one or three-year interest rate boost.
(20) Dangers such as bed- and tub-sharing, diaper and cleaning pails, plastic wrappers, balloons, small beds, toys on strings, broken or poorly designed cribs, and poorly positioned adult beds must be brought to the attention of the parent as consumer.