(a.) The act of mediating; action or relation of anything interposed; action as a necessary condition, means, or instrument; interposition; intervention.
(a.) Hence, specifically, agency between parties at variance, with a view to reconcile them; entreaty for another; intercession.
Example Sentences:
(1) Stimulation of human leukocytes with various chemical mediators such as TPA, f-Met-Leu-Phe, LTB4, etc.
(2) Fibulin is a potential mediator of interactions between adhesion receptors and the cytoskeleton.
(3) Patients with papillary carcinoma with a good cell-mediated immune response occurred with much lower infiltration of the tumor boundary with lymphocyte whereas the follicular carcinoma less cell-mediated immunity was associated with dense lymphocytic infiltration, suggesting the biological relevance of lymphocytic infiltration may be different for the two histologic variants.
(4) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(5) We have investigated the effect of methimazole (MMI) on cell-mediated immunity and ascertained the mechanisms of immunosuppression produced by the drug.
(6) We determined whether serological investigations can assist to distinguish between chronic idiopathic autoimmune thrombocytopenia (cAITP) and immune-mediated thrombocytopenia in patients at risk to develop systemic lupus erythematosus (SLE); 82 patients were seen in this institution for the evaluation of immune thrombocytopenia.
(7) IgE-mediated acute systemic reactions to penicillin continue to be an important clinical problem.
(8) This induction is sensitive to actinomycin D but not to protein synthesis inhibitor puromycin, indicating an effect of estradiol at the transcriptional level, possibly mediated by the estrogen receptor.
(9) We sought additional evidence for an inverse relationship between functional CTL-target cell affinity on the one hand, and susceptibility of the CTL-mediated killing to inhibition by alpha LFA-1 and alpha Lyt-2,3 monoclonal antibodies on the other hand.
(10) Mannose receptor mediated uptake by the reticuloendothelial system has been suggested as an explanation for the rapid removal of ricin A chain antibody conjugates from the circulation after their administration.
(11) However, direct measurements of mediator release should be carried out to reach a firm conclusion.
(12) In addition to their involvement in thrombosis, activated platelets release growth factors, most notably a platelet-derived growth factor (PDGF) which may be the principal mediator of smooth muscle cell migration from the media into the intima and of smooth muscle cell proliferation in the intima as well as of vasoconstriction.
(13) Glutathion peroxidase and p-phenylenediamide-mediated peroxidase (PPD-peroxidase) were normal in leucocytes of 1 HPS patient.
(14) But MH162 was more effective than MRK16 in lymphocyte-mediated lysis of the MDR cells.
(15) Thus, human bronchial epithelial cells can express the IL-8 gene, with expression in response to the inflammatory mediator TNF regulated mainly at the transcriptional level, and with elements within the 5'-flanking region of the gene that are directly or indirectly modulated by the TNF signal.
(16) Tumour necrosis factor (TNF), a polypeptide produced by mononuclear phagocytes, has been implicated as an important mediator of inflammatory processes and of clinical manifestations in acute infectious diseases.
(17) From these results, it was suggested that the inhibitory effect of Cd on in vitro calcification of MC3T3-E1 cells may be due to both a depression of cell-mediated calcification and a decrease in physiochemical mineral deposition.
(18) injection of various inflammatory mediators, the vasopressor effect of i.a.
(19) It is concluded that fibroblast replication is an important mechanism leading to the pathologic fibrosis seen in graft versus host disease and, by analogy, probably other types of immunologically mediated fibrosis.
(20) The authors followed up the occurrence of inflammation-mediated osteopenia (IMO) in young and adult rats weighing 50 g and 150 g, respectively.
Mid
Definition:
(superl.) Denoting the middle part; as, in mid ocean.
(superl.) Occupying a middle position; middle; as, the mid finger; the mid hour of night.
(superl.) Made with a somewhat elevated position of some certain part of the tongue, in relation to the palate; midway between the high and the low; -- said of certain vowel sounds; as, a (ale), / (/ll), / (/ld). See Guide to Pronunciation, // 10, 11.
(n.) Middle.
(prep.) See Amid.
Example Sentences:
(1) In contrast to L2 and L3 in L1 the mid gut runs down in a straight line without any looping.
(2) Basal 20 alpha DHP levels remained low until a sharp rise at mid pro-oestrus.
(3) It did the job of triggering growth, but it also fueled real-estate speculation, similar to what was going on in the mid-2000s here.” Slowing economic growth may be another concern.
(4) For consistent identification of the normal pancreas, preliminary longitudinal scanning at, or near, the mid-line and subsequent oblique scanning in the long axis are necessary prerequisites in delineating the anatomic outline of the pancreas.
(5) Patients with MID, but not those with DAT, exhibited correlations between enlargement of the third and lateral ventricles and severity of cognitive impairment.
(6) Meanwhile, Hunt has been accused of backtracking on a key recommendation in the official report into Mid Staffs.
(7) Hatching commenced in early October (after 23 wk), when air and water temperatures decreased to 20 and 15 degrees C, respectively, and continued until mid-December (32 wk) in the field.
(8) Retrognathia or retrusion of the maxilla and mid-face is present in about one-third of treated cleft palate patients.
(9) Heptathletes peak in their mid-to-late twenties – two Olympic cycles away yet for Johnson-Thompson – so what would she like to achieve in London?
(10) Robert Francis QC's official report in February on the Mid Staffordshire care scandal, in which an estimated 400 to 1,200 patients died unnecessarily at Stafford hospital between 2005 and 2008, called for the NHS to make "zero harm" its objective.
(11) It was found that within the dorsal part of the well known pressor area there is a narrow strip, 2.5 mm lateral from the mid line, starting ventral to the inferior colliculus and ending in the medulla close to the floor of the IV ventricle, from which vasodilatation in skeletal muscles is selectively obtained.
(12) But for the mid Atlantic, the models showed that only human-driven global warming could explain the increase in saltiness – the first time such an explicit link has been made between climate change and salinity.
(13) Another 300-350 civilians had been killed and 600-650 injured from late January to mid-April.
(14) A Teflon cylinder was placed in the mid-left anterior descending coronary artery to create a 33% stenosis.
(15) Recombination activity was found to be low in G1 and to rise 10- to 15-fold, peaking in early to mid-S phase.
(16) His bundle recordings and premature atrial stimulation from coronary sinus, mid-right atrium and high-right atrium were performed in a patient with repetitive supraventricular tachycardias.
(17) But when in mid-October two of the artists received death threats, the menaces were widely reported and rekindled debate, prompting vicious, anti-Muslim comments on Danish talk shows.
(18) The plans would eventually double the numbers of passengers at the Sussex airport, which believes its current capacity to grow from 34 million to 45 million with a single runway will see it through until the mid-2020s.
(19) In proliferative retinopathy, the mid-vitreous fluorophotometry readings were abnormally increased, correlating well with the extent of the peripheral angiographic changes (neovascularization).
(20) The 0.3 M NaCl intake of the high NaCl-exposed rats was also significantly greater than the intake of the mid and low NaCl-exposed rats.