(a.) The act of mediating; action or relation of anything interposed; action as a necessary condition, means, or instrument; interposition; intervention.
(a.) Hence, specifically, agency between parties at variance, with a view to reconcile them; entreaty for another; intercession.
Example Sentences:
(1) Stimulation of human leukocytes with various chemical mediators such as TPA, f-Met-Leu-Phe, LTB4, etc.
(2) Fibulin is a potential mediator of interactions between adhesion receptors and the cytoskeleton.
(3) Patients with papillary carcinoma with a good cell-mediated immune response occurred with much lower infiltration of the tumor boundary with lymphocyte whereas the follicular carcinoma less cell-mediated immunity was associated with dense lymphocytic infiltration, suggesting the biological relevance of lymphocytic infiltration may be different for the two histologic variants.
(4) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(5) We have investigated the effect of methimazole (MMI) on cell-mediated immunity and ascertained the mechanisms of immunosuppression produced by the drug.
(6) We determined whether serological investigations can assist to distinguish between chronic idiopathic autoimmune thrombocytopenia (cAITP) and immune-mediated thrombocytopenia in patients at risk to develop systemic lupus erythematosus (SLE); 82 patients were seen in this institution for the evaluation of immune thrombocytopenia.
(7) IgE-mediated acute systemic reactions to penicillin continue to be an important clinical problem.
(8) This induction is sensitive to actinomycin D but not to protein synthesis inhibitor puromycin, indicating an effect of estradiol at the transcriptional level, possibly mediated by the estrogen receptor.
(9) We sought additional evidence for an inverse relationship between functional CTL-target cell affinity on the one hand, and susceptibility of the CTL-mediated killing to inhibition by alpha LFA-1 and alpha Lyt-2,3 monoclonal antibodies on the other hand.
(10) Mannose receptor mediated uptake by the reticuloendothelial system has been suggested as an explanation for the rapid removal of ricin A chain antibody conjugates from the circulation after their administration.
(11) However, direct measurements of mediator release should be carried out to reach a firm conclusion.
(12) In addition to their involvement in thrombosis, activated platelets release growth factors, most notably a platelet-derived growth factor (PDGF) which may be the principal mediator of smooth muscle cell migration from the media into the intima and of smooth muscle cell proliferation in the intima as well as of vasoconstriction.
(13) Glutathion peroxidase and p-phenylenediamide-mediated peroxidase (PPD-peroxidase) were normal in leucocytes of 1 HPS patient.
(14) But MH162 was more effective than MRK16 in lymphocyte-mediated lysis of the MDR cells.
(15) Thus, human bronchial epithelial cells can express the IL-8 gene, with expression in response to the inflammatory mediator TNF regulated mainly at the transcriptional level, and with elements within the 5'-flanking region of the gene that are directly or indirectly modulated by the TNF signal.
(16) Tumour necrosis factor (TNF), a polypeptide produced by mononuclear phagocytes, has been implicated as an important mediator of inflammatory processes and of clinical manifestations in acute infectious diseases.
(17) From these results, it was suggested that the inhibitory effect of Cd on in vitro calcification of MC3T3-E1 cells may be due to both a depression of cell-mediated calcification and a decrease in physiochemical mineral deposition.
(18) injection of various inflammatory mediators, the vasopressor effect of i.a.
(19) It is concluded that fibroblast replication is an important mechanism leading to the pathologic fibrosis seen in graft versus host disease and, by analogy, probably other types of immunologically mediated fibrosis.
(20) The authors followed up the occurrence of inflammation-mediated osteopenia (IMO) in young and adult rats weighing 50 g and 150 g, respectively.
Mobile
Definition:
(a.) Capable of being moved; not fixed in place or condition; movable.
(a.) Characterized by an extreme degree of fluidity; moving or flowing with great freedom; as, benzine and mercury are mobile liquids; -- opposed to viscous, viscoidal, or oily.
(a.) Easily moved in feeling, purpose, or direction; excitable; changeable; fickle.
(a.) Changing in appearance and expression under the influence of the mind; as, mobile features.
(a.) Capable of being moved, aroused, or excited; capable of spontaneous movement.
(a.) The mob; the populace.
Example Sentences:
(1) It was found that linear extrapolations of log k' versus ET(30) plots to the polarity of unmodified aqueous mobile phase gave a more reliable value of log k'w than linear regressions of log k' versus volume percent.
(2) The mobility on sodium dodecyl sulfate-polyacrylamide gel electrophoresis is anomalous since the undenatured, cross-linked proteins have the same Stokes radius as the native, uncross-linked alpha beta gamma heterotrimer.
(3) It is likely that trunk mobility is necessary to maintain integrity of SI joint and that absence of such mobility compromises SI joint structure in many paraplegics.
(4) Their particular electrophoretic mobility was retained.
(5) This mobilization procedure allowed transfer and expression of pJT1 Ag+ resistance in E. coli C600.
(6) A substance with a chromatographic mobility of Rf = 0.8 on TLC plates having an intact phosphorylcholine head group was also formed but has not yet been identified.
(7) The following model is suggested: exogenous ATP interacts with a membrane receptor in the presence of Ca2+, a cascade of events occurs which mobilizes intracellular calcium, thereby increasing the cytosolic free Ca2+ concentration which consequently opens the calcium-activated K+ channels, which then leads to a change in membrane potential.
(8) Sequence specific binding of protein extracts from 13 different yeast species to three oligonucleotide probes and two points mutants derived from Saccharomyces cerevisiae DNA binding proteins were tested using mobility shift assays.
(9) The molecule may already in its native form have an extended conformation containing either free sulfhydryl groups or small S-S loops not affecting mobility in SDS-PAGE.
(10) Furthermore, carcinoembryonic antigen from the carcinoma tissue was found to have the same electrophoretical mobility as the UEA-I binding glycoproteins.
(11) There was immediate resolution of paresthesia following mobilization of the impinging vessel from the nerve.
(12) The last stems from trends such as declining birth rate, an increasingly mobile society, diminished importance of the nuclear family, and the diminishing attractiveness of professions involved with providing maintenance care.
(13) In order to obtain the most suitable mobile phase, we studied the influence of pH and acetonitrile content on the capacity factor (k').
(14) Here is the reality of social mobility in modern Britain.
(15) This includes cutting corporation tax to 20%, the lowest in the G20, and improving our visa arrangements with a new mobile visa service up and running in Beijing and Shanghai and a new 24-hour visa service on offer from next summer.
(16) The toxins preferentially attenuate a slow phase of KCl-evoked glutamate release which may be associated with synaptic vesicle mobilization.
(17) Heparitinase I (EC 4.2.2.8), an enzyme with specificity restricted to the heparan sulfate portion of the polysaccharide, releases fragments with the electrophoretic mobility and the structure of heparin.
(18) The transference by conjugation of protease genetic information between Proteus mirabilis strains only occurs upon mobilization by a conjugative plasmid such as RP4 (Inc P group).
(19) Lady Gaga is not the first big music star to make a new album available early to mobile customers.
(20) Moreover, it is the recombinant p70 polypeptides of slowest mobility that coelute with S6 kinase activity on anion-exchange chromatography.