(a.) The act of mediating; action or relation of anything interposed; action as a necessary condition, means, or instrument; interposition; intervention.
(a.) Hence, specifically, agency between parties at variance, with a view to reconcile them; entreaty for another; intercession.
Example Sentences:
(1) Stimulation of human leukocytes with various chemical mediators such as TPA, f-Met-Leu-Phe, LTB4, etc.
(2) Fibulin is a potential mediator of interactions between adhesion receptors and the cytoskeleton.
(3) Patients with papillary carcinoma with a good cell-mediated immune response occurred with much lower infiltration of the tumor boundary with lymphocyte whereas the follicular carcinoma less cell-mediated immunity was associated with dense lymphocytic infiltration, suggesting the biological relevance of lymphocytic infiltration may be different for the two histologic variants.
(4) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(5) We have investigated the effect of methimazole (MMI) on cell-mediated immunity and ascertained the mechanisms of immunosuppression produced by the drug.
(6) We determined whether serological investigations can assist to distinguish between chronic idiopathic autoimmune thrombocytopenia (cAITP) and immune-mediated thrombocytopenia in patients at risk to develop systemic lupus erythematosus (SLE); 82 patients were seen in this institution for the evaluation of immune thrombocytopenia.
(7) IgE-mediated acute systemic reactions to penicillin continue to be an important clinical problem.
(8) This induction is sensitive to actinomycin D but not to protein synthesis inhibitor puromycin, indicating an effect of estradiol at the transcriptional level, possibly mediated by the estrogen receptor.
(9) We sought additional evidence for an inverse relationship between functional CTL-target cell affinity on the one hand, and susceptibility of the CTL-mediated killing to inhibition by alpha LFA-1 and alpha Lyt-2,3 monoclonal antibodies on the other hand.
(10) Mannose receptor mediated uptake by the reticuloendothelial system has been suggested as an explanation for the rapid removal of ricin A chain antibody conjugates from the circulation after their administration.
(11) However, direct measurements of mediator release should be carried out to reach a firm conclusion.
(12) In addition to their involvement in thrombosis, activated platelets release growth factors, most notably a platelet-derived growth factor (PDGF) which may be the principal mediator of smooth muscle cell migration from the media into the intima and of smooth muscle cell proliferation in the intima as well as of vasoconstriction.
(13) Glutathion peroxidase and p-phenylenediamide-mediated peroxidase (PPD-peroxidase) were normal in leucocytes of 1 HPS patient.
(14) But MH162 was more effective than MRK16 in lymphocyte-mediated lysis of the MDR cells.
(15) Thus, human bronchial epithelial cells can express the IL-8 gene, with expression in response to the inflammatory mediator TNF regulated mainly at the transcriptional level, and with elements within the 5'-flanking region of the gene that are directly or indirectly modulated by the TNF signal.
(16) Tumour necrosis factor (TNF), a polypeptide produced by mononuclear phagocytes, has been implicated as an important mediator of inflammatory processes and of clinical manifestations in acute infectious diseases.
(17) From these results, it was suggested that the inhibitory effect of Cd on in vitro calcification of MC3T3-E1 cells may be due to both a depression of cell-mediated calcification and a decrease in physiochemical mineral deposition.
(18) injection of various inflammatory mediators, the vasopressor effect of i.a.
(19) It is concluded that fibroblast replication is an important mechanism leading to the pathologic fibrosis seen in graft versus host disease and, by analogy, probably other types of immunologically mediated fibrosis.
(20) The authors followed up the occurrence of inflammation-mediated osteopenia (IMO) in young and adult rats weighing 50 g and 150 g, respectively.
Resolution
Definition:
(n.) The act, operation, or process of resolving. Specifically: (a) The act of separating a compound into its elements or component parts. (b) The act of analyzing a complex notion, or solving a vexed question or difficult problem.
(n.) The state of being relaxed; relaxation.
(n.) The state of being resolved, settled, or determined; firmness; steadiness; constancy; determination.
(n.) That which is resolved or determined; a settled purpose; determination. Specifically: A formal expression of the opinion or will of an official body or a public assembly, adopted by vote; as, a legislative resolution; the resolutions of a public meeting.
(n.) The state of being resolved or firm in opinion or thought; conviction; assurance.
(n.) The act or process of solving; solution; as, the resolution of an equation or problem.
(n.) A breaking up, disappearance; or termination, as of a fever, a tumor, or the like.
(n.) The passing of a dissonant into a consonant chord by the rising or falling of the note which makes the discord.
Example Sentences:
(1) Direct fetal digitalization led to a reduction in umbilical artery resistance, a decline in the abdominal circumference from 20.3 to 17.8 cm, and resolution of the ascites within 72 h. Despite this dramatic response to therapy, fetal death occurred on day 5 of treatment.
(2) Thyroid replacement led to resolution of both apnea and depression.
(3) Multiple overlapping thin 3D slab acquisition is presented as a magnitude contrast (time of flight) technique which combines advantages from multiple thin slice 2D and direct 3D volume acquisitions to obtain high-resolution cross-sectional images of vessel detail.
(4) The RNA polymerase activity was tested after the solubilization and chromatographic resolution of the three types of polymerases with exogenous template.
(5) Technical manipulations to improve resolution were time consuming and added little to the accuracy of the test.
(6) We are pleased to see the process moving forward and look forward to its resolution,” a Target spokeswoman, Molly Snyder, said in an emailed statement.
(7) It is commonly assumed that the visual resolution limit must be equal to or less than the Nyquist frequency of the cone mosaic.
(8) Limitations include the facts that the tracer inventory requires a minimal survival period, can only be done postmortem, and has low resolution for cuts of the vagal hepatic branch.
(9) There was immediate resolution of paresthesia following mobilization of the impinging vessel from the nerve.
(10) The probable reaction mechanisms prevailing in both cases are discussed in accordance with the low and high resolution mass spectral data presented.
(11) It is found that, whereas the spatial resolution achievable with such a system is only dependent upon its temporal resolution, the scattering characteristics of the tissue being imaged will strongly affect the ultimate imaging performance of such a system.
(12) After permeabilization, with attendant partial extraction, the preparation can be fixed, then viewed by either deep-etch replication, or by high-resolution scanning electron microscopy, with structure of interest revealed in deep view.
(13) The data collection scheme for the scanner uses multiple rotations of a linearly shifted, asymmetric fan beam permitting user-defined variable resolution.
(14) The model electron density map, calculated to a resolution of approximately 35 A, shows an unusually high protein content in the membranes.
(15) A technique is therefore described using 3-D images and reconstruction of high-resolution films, which allows rapid examination of the menisci in optimal planes.
(16) Analysis of Alu repeat polymorphism should be useful in construction of a high-resolution map and also in identifying genotypes of individuals for clinical and other purposes because the repeats are ubiquitous and the technique for their detection is simple.
(17) The most controversial part of the resolution is the stop and search powers.
(18) For application to mammalian cells, however, two serious problems require resolution: (1), correction of TPP+ binding to intracellular constituents and (2), estimation of the considerable TPP+ accumulation in mitochondria.
(19) Two high-resolution (Hi-Res) ECG systems (MAC-12, Marquette Electronics, Inc (MEI), Milwaukee, WI and LVP101, Arrhythmia Research Technology (ART), Austin, TX) were tested on 143 subjects (13 controls and 130 cardiac patients, 21 of whom were tested for inducible ventricular tachycardia [VT]).
(20) The spatial resolution of a NaI(T1), 25 mm thick bar detector designed for use in positron emission tomography has been studied.