(1) In dogs, H1-receptor stimulation with 2-MeH induced pulmonary vasoconstriction, and a decrease in cardiac output.
(2) Assays were optimized for time, pH, and temperature, using trans-stilbene oxide (TSO) and cis-stilbene oxide (CSO) as substrates for cEH and mEH, respectively.
(3) PGE1, PGF2alpha and 4-methylhistamine (4-MeH: a relatively specific H2-receptor agonist) contract pulmonary arterial strips but further increase in the dose of PGE1 produces relaxation.
(4) Gathering fasting and TPN data MEH excretion was significantly related to both body (r = 0.89) and muscle (r = 0.73) NB, that were highly related to each other (r = 0.93), being muscle always worse than body NB.
(5) The reaction from Wall Street traders is more often along the lines of "meh".
(6) Thus, the hypothalamus-pituitary-adrenal axis is involved in the regulation of mEH but the regulation of the cEH enzyme remains unclear.
(7) In microsomal fractions, enzyme activities measured were pentoxyresorufin O-dealkylase (PROD), ethoxyresorufin O-dealkylase (EROD), and epoxide hydrolase (mEH).
(8) Using benzo[alpha]pyrene-4,5-oxide as substrate, mEH enzymatic activity is shown to correlate closely with tissue levels of mEH mRNA.
(9) The study demonstrates that the balance between activation of CBZ by the cytochrome P450 enzymes to a chemically reactive arene oxide metabolite and its detoxification by mEH and GSH may contribute to individual susceptibility to CBZ idiosyncratic toxicity.
(10) Thus, the pituitary appears to be important in the developmental induction of mEH but not cEH.
(11) 'Hermless, hermless, there's never nae bather fae me, I go to the library, I tak oot a book, and then I go hame for meh tea.'"
(12) Immunoblot analyses revealed that hepatic mEH levels in males increased in an age-dependent manner, with a maximal increase (approximately 3-fold) being noted at 44 weeks of age, whereas the expression of hepatic mEH in females decreased significantly at 14 weeks of age or older, by approximately 70%s, compared with that of 4-week-old rats.
(13) The possible role of the secretion from the Mehlis' gland in egg-shell formation is discussed.
(14) The excretion of the amino acid 3-methylhistidine (3-MeH), an indicator of muscle protein breakdown, and urea nitrogen loss were measured in the urine collected the day before, and on the 2nd and 4th postoperative days.
(15) Urinary excretion of urea nitrogen and 3-methylhistidine (3-MeH) after surgery was significantly lower in the warmed group compared with the cold group (P less than 0.05).
(16) These results provide evidence that the imidazole antimycotic agents induce mEH and that the mEH induction involves large increases in mRNA, with transcriptional activation.
(17) Morphological studies revealed the following major characteristics for 35 day-old worms: the mean length of the terminal segment accounted for 54% of the total worm length; the position of the sexually mature segment was always terminal; the female reproductive system possessed an elongated ovary with compact lobules; the female ducts were also compact; the Mehlis' gland was covered by the vitelline gland and the testes were distributed throughout the segment, with 1 row posterior to the vitelline gland.
(18) We have assessed the effects of glutamine (Gln) availability on protein breakdown in perfused rat hindlimb by measuring net phenylalanine (Phe) production (an index of protein balance), the dilution of [15N]Phe labelling (an index of mixed protein breakdown) and rate of production of 3-methylhistidine (3-MeH) (an index of myofibrillar breakdown).
(19) Clotrimazole, however, maintained the activated mEH transcription rate at 24 hr after treatment, exhibiting a 11-fold increase, compared with control.
(20) Immunoblot analyses revealed that administration of either ketoconazole or clotrimazole caused a approximately 4-5-fold increase in mEH levels, whereas either miconazole or econazole resulted in a approximately 7-fold increase in mEH at day 3 after treatment.
Mew
Definition:
(n.) A gull, esp. the common British species (Larus canus); called also sea mew, maa, mar, mow, and cobb.
(v. t.) To shed or cast; to change; to molt; as, the hawk mewed his feathers.
(v. i.) To cast the feathers; to molt; hence, to change; to put on a new appearance.
(n.) A cage for hawks while mewing; a coop for fattening fowls; hence, any inclosure; a place of confinement or shelter; -- in the latter sense usually in the plural.
(n.) A stable or range of stables for horses; -- compound used in the plural, and so called from the royal stables in London, built on the site of the king's mews for hawks.
(v. t.) To shut up; to inclose; to confine, as in a cage or other inclosure.
(v. i.) To cry as a cat.
(n.) The common cry of a cat.
Example Sentences:
(1) The Blairs' property portfolio already includes a £3.6m townhouse and an £800,000 adjoining mews house in Connaught Square, London, two flats in Bristol and the constituency home in Trimdon, Co Durham, which Blair bought when he was elected MP for Sedgefield in 1983.
(2) Map Neighbour Iwona Romek said Masood was a keen gardener, who lived in the modern mews house with his wife and young child.
(3) But the scene in the 250-seater conference centre on an unassuming cobbled mews in central London was a far more serene affair.
(4) Steven Wood, associate in social housing litigation at Coffin Mew LLP "The housing strategy for England is hailed as 'radical and unashamedly ambitious' but at first blush appears to predominantly be a recycling of ideas that are already out to consultation or at various stages of being enacted by changes in the law.
(5) So "out" becomes "iouuut", and "now" "niouuuw", a bit – with all due respect to her beloved dogs – like the mewing of a cat.
(6) Glutamine synthetase (GS) activity was used as a marker to examine differences in astrocyte development in mice selectively bred for ethanol sensitivity: long sleep (LS), short sleep (SS), mild ethanol withdrawal (MEW), severe ethanol withdrawal (SEW) and control ethanol withdrawal (CEW).
(7) A female infant presented at birth with hypotonia, growth retardation, distinctive facies, multiple congenital anomalies, and a high-pitched mewing cry characteristic of cri du chat syndrome.
(8) We meet once a week to make sure that Jason Mewes stays on the straight and narrow.
(9) Although it indicated the increase in heart water in the crystalloid group, it proved less reliable in the measurement of MEW in this dynamic situation.
(10) It claims that the changes include "wayfinder" signs to help staff find their way around named after BBC TV hits, such as Have I Got Mews, Little Britain's Passage, EastEnders Common, Who Do You Think You Arcade and The Great British Bake Wharf.
(11) A 12-year-old boy with a history of a mewing cry after birth, severe mental retardation, Marfanoid arachnodactyly, general osteomalacia and multiple bone fractures was found to have a de novo 5p;12q chromosomal translocation.
(12) These results indicate that the SCN-mEW circuit in birds may be involved in mediating increases in choroidal blood flow, possibly in response to the levels of retinal illumination.
(13) Anatomical studies in birds have suggested that choroidal blood flow may be regulated by a circuit involving the following serially-connected components: the retina-the suprachiasmatic nucleus (SCN)-the medial subdivision of the nucleus of Edinger-Westphal (mEW)-the ciliary ganglion-the choroidal blood vessels.
(14) Now scaled back to a total of 8,000 homes, the "legacy communities" will be formed from familiar things: terraces and squares, mansion blocks and mews houses.
(15) The Peacock industrial estate, currently fully occupied with garages and other businesses, is to be knocked down in two of the options, and become Peacock Mews.
(16) The cri-du-chat syndrome is characterized by a peculiar high-pitched, mewing cry and can be differentiated from the Wolf syndrome by the different staining characteristics (banding) of chromosomes 4 and 5.
(17) With his wife, Frannie, he bought a mews cottage in Kensington, central London, where he stocked up with luxuries purchased by friends from Harrods and from Christopher's in Jermyn Street, where he had a regular order for a dozen bottles of Veuve Clicquot champagne.
(18) The 24-year-old victim is recovering in hospital from injuries to her lower body after the attack, which happened at about 10.40pm on Wednesday night on Lord Street Mews, a cul-de-sac off the Beersbridge Road.
(19) Since moving out of Downing Street, Blair's London home has been a capacious cream and dark brick terrace in Connaught Square, near Hyde Park, with a substantial mews house behind and armed policemen perpetually guarding both.
(20) We found that 1) GS activity in MEW and SEW was higher than in LS and SS during the first 2 weeks of postnatal development, in the forebrain but not in the cerebellum; 2) lower GS activity was observed consistently in all areas examined with the SS mice as compared to the LS; 3) glutamine synthetase activity in MEW and SEW differed significantly from their controls (CEW) during the early developmental period regardless of the brain region examined; however, after 30 days of maturation, GS activity in SEW was higher than that in MEW and CEW in the forebrain.