(1) In dogs, H1-receptor stimulation with 2-MeH induced pulmonary vasoconstriction, and a decrease in cardiac output.
(2) Assays were optimized for time, pH, and temperature, using trans-stilbene oxide (TSO) and cis-stilbene oxide (CSO) as substrates for cEH and mEH, respectively.
(3) PGE1, PGF2alpha and 4-methylhistamine (4-MeH: a relatively specific H2-receptor agonist) contract pulmonary arterial strips but further increase in the dose of PGE1 produces relaxation.
(4) Gathering fasting and TPN data MEH excretion was significantly related to both body (r = 0.89) and muscle (r = 0.73) NB, that were highly related to each other (r = 0.93), being muscle always worse than body NB.
(5) The reaction from Wall Street traders is more often along the lines of "meh".
(6) Thus, the hypothalamus-pituitary-adrenal axis is involved in the regulation of mEH but the regulation of the cEH enzyme remains unclear.
(7) In microsomal fractions, enzyme activities measured were pentoxyresorufin O-dealkylase (PROD), ethoxyresorufin O-dealkylase (EROD), and epoxide hydrolase (mEH).
(8) Using benzo[alpha]pyrene-4,5-oxide as substrate, mEH enzymatic activity is shown to correlate closely with tissue levels of mEH mRNA.
(9) The study demonstrates that the balance between activation of CBZ by the cytochrome P450 enzymes to a chemically reactive arene oxide metabolite and its detoxification by mEH and GSH may contribute to individual susceptibility to CBZ idiosyncratic toxicity.
(10) Thus, the pituitary appears to be important in the developmental induction of mEH but not cEH.
(11) 'Hermless, hermless, there's never nae bather fae me, I go to the library, I tak oot a book, and then I go hame for meh tea.'"
(12) Immunoblot analyses revealed that hepatic mEH levels in males increased in an age-dependent manner, with a maximal increase (approximately 3-fold) being noted at 44 weeks of age, whereas the expression of hepatic mEH in females decreased significantly at 14 weeks of age or older, by approximately 70%s, compared with that of 4-week-old rats.
(13) The possible role of the secretion from the Mehlis' gland in egg-shell formation is discussed.
(14) The excretion of the amino acid 3-methylhistidine (3-MeH), an indicator of muscle protein breakdown, and urea nitrogen loss were measured in the urine collected the day before, and on the 2nd and 4th postoperative days.
(15) Urinary excretion of urea nitrogen and 3-methylhistidine (3-MeH) after surgery was significantly lower in the warmed group compared with the cold group (P less than 0.05).
(16) These results provide evidence that the imidazole antimycotic agents induce mEH and that the mEH induction involves large increases in mRNA, with transcriptional activation.
(17) Morphological studies revealed the following major characteristics for 35 day-old worms: the mean length of the terminal segment accounted for 54% of the total worm length; the position of the sexually mature segment was always terminal; the female reproductive system possessed an elongated ovary with compact lobules; the female ducts were also compact; the Mehlis' gland was covered by the vitelline gland and the testes were distributed throughout the segment, with 1 row posterior to the vitelline gland.
(18) We have assessed the effects of glutamine (Gln) availability on protein breakdown in perfused rat hindlimb by measuring net phenylalanine (Phe) production (an index of protein balance), the dilution of [15N]Phe labelling (an index of mixed protein breakdown) and rate of production of 3-methylhistidine (3-MeH) (an index of myofibrillar breakdown).
(19) Clotrimazole, however, maintained the activated mEH transcription rate at 24 hr after treatment, exhibiting a 11-fold increase, compared with control.
(20) Immunoblot analyses revealed that administration of either ketoconazole or clotrimazole caused a approximately 4-5-fold increase in mEH levels, whereas either miconazole or econazole resulted in a approximately 7-fold increase in mEH at day 3 after treatment.
Uninspiring
Definition:
Example Sentences:
(1) But there can be few elections where the choice is as uninspiring as this.
(2) The Coalition is appealing to the same change-weary voters with the message that Turnbull is a better bet to deliver economic and political stability and Shorten is untested, uninspiring and a risk.
(3) Facebook Twitter Pinterest The Venetian Condos in Oliver Unfortunately, Edmonton has a lot of rather odd and uninspired architecture, particularly that dating from the 1990s and early 2000s.
(4) Manchester City had not won since Sergio Agüero’s last goal, away against Swansea City on 24 September, but seven games later the Argentina striker found the net twice in the first half to catapult Pep Guardiola’s team past an uninspiring West Bromwich Albion and back to the top of the table, where Arsenal had momentarily displaced them earlier in the afternoon.
(5) Occasionally Beckerman would start in the Jones role, but the effect of him alongside Bradley seemed to be very static and uninspiring.
(6) The standard of opposition is, in part, to make up for a generally uninspiring fixture list in their qualifying group.
(7) Polls put Romney ahead by two percentage points on Thursday and, after delivering a competent but uninspired speech on Thursday evening, one point on Friday.
(8) City were sluggish and uninspired, and though Dzeko hit the bar with a powerful header just before Southampton levelled, he should have done better from Nasri's well-flighted free-kick.
(9) Yet it also includes hundreds of longstanding activists who did the same to register their discontent with what they felt to be a shrunken, inauthentic and uninspiring offer from the Labour mainstream.
(10) While a less crushing defeat is expected this time, analysts are not predicting significant gains for fragmented, uninspired opponents that have wilted under the EPRDF’s glare.
(11) Or, if you prefer, Barney Ronay's analysis of a "turgid, tactically constipated semi-final”, "a deeply uninspiring match", "a game of no shots, no incident and a crushing sense of caution", "120 minutes of something that resembled a groggy second cousin of high-grade tournament football".
(12) Miguel Herrera's side may have had a fairly uninspiring qualification campaign but they have already proved that they can kick it with the best of them and with the rest of them.
(13) They are uninspiring, do not challenge able students and certainly do not prepare students for an A-level course.
(14) Villa were flat and uninspiring, on the wrong end of a game of keep-ball, and, if Lambert's move for Grant Holt of Wigan Athletic smacks a little of desperation, it is because their record of eight home goals in the league is as bad as it gets in all four divisions.
(15) It looked as though the teams would play out an uninspiring 0-0 draw after 90 minutes that had end of season stamped all over them.
(16) Those are: Labor’s me-tooism on asylum-seekers that offend a moral conscience of idealistic campaigners, me-tooism on mass surveillance that infuriates an entire digital community of potential communicators, and employing the language of uninspiring bureaucracy around the progressive policy opportunity which is climate action.
(17) It detailed a string of failures: that staff training on how to prevent radicalism and extremism was not completed; there were issues around safeguarding, declining academic standards, uninspiring teaching, low expectations and low attendance.
(18) Their campaign has been arid and uninspiring so far and they must hope that the public does not grow resentful of their persistent claims that Scotland isn't big enough or good enough to stand alone.
(19) Sifting through a mountain of unwelcome tweets, many Twitter users would sympathise with a lament such as: "Most comments are predictably ludicrous, irrational and uninspiring and, therefore, do not warrant the time for a response."
(20) Photograph: PR company handout Creatively, it’s all a bit uninspiring, but there are passable moments.