(n.) A kind of mental unsoundness characterized by extreme depression of spirits, ill-grounded fears, delusions, and brooding over one particular subject or train of ideas.
Example Sentences:
(1) The authors took multiple serum samples for measurement of melatonin between 4:30 p.m. and 7:30 a.m. in seven male depressed patients with melancholia and five healthy male control subjects and found that melancholic patients had a significantly lower rise of melatonin.
(2) The patients were categorized according to DSM-III as suffering from either minor depression (including dysthymic disorder, 300.40; adjustment disorder with depressed mood, 309.00; atypical depression, 296.82) or major depression (without melancholia, 296.X2; with melancholia, 296.X3; with psychotic features, 296.X4).
(3) Von Trier, who took a " vow of silence " after being banned from the Cannes film festival in 2011 after joking about Nazism during a press conference for Melancholia, arrived at Nymphomaniac's photocall wearing a T-shirt emblazoned with the phrase "Persona Non Grata"; true to his word, he failed to attend the subsequent press conference where his actors and producer talked about the film.
(4) This study reports an open clinical trial in which seven of eight outpatients (88%) with melancholia responded to phenelzine treatment.
(5) Speaking at a press conference following the preview of his latest film, Melancholia, von Trier expressed sympathy for Hitler, remarked that Israel was "a pain in the arse" and jokingly confessed to being a Nazi .
(6) With the Extracted Criteria, initial insomnia, early waking, anorexia, weight loss, loss of libido, and worsened mood in the morning were all significantly more common in melancholia than in non-melancholic depression, while increased appetite was more common in non-melancholia.
(7) The first, or maybe, occurrence of the word "melancholia" is found in a French mediaeval book "Knight Yvain" (12th century).
(8) Patients with endogenous depression (melancholia) as defined by each of ICD-9, DSM-III, RDC and Newcastle scale demonstrated a reduced prolactin response to 60 mg oral fenfluramine when compared with non-endogenous subjects.
(9) We performed the DST in 95 depressed inpatients to determine whether abnormal DST results were associated with individual symptoms of depression, latent behavioral "factors," melancholia, or severity of depression.
(10) Neurotic subtyping was significantly negatively associated with DSM-III melancholia.
(11) In this study an evaluation of the inter-rater reliability of the Hamilton Depression Rating Scale, the Melancholia Scale and the Montgomery-Asberg Depression Rating Scale has been carried out.
(12) We also studied a group of depressed patients without melancholia (n = 11) with mean age 65.2 years, and found a similar, but less pronounced, alteration of the FVER.
(13) The Danish director was thrown out of the festival for dim comments made about Hitler at the press conference after his film Melancholia , although the film itself bizarrely remains in with a chance of prizes tonight, with its star Kirsten Dunst having particularly impressed Robert De Niro and his jury, I hear.
(14) This kind of acting is in fact also observed in melancholia, psychoses and prepsychotic states, depressions with jealousy, borderlines and the actors of "accompanied suicides".
(15) Non-suppression was found in most of the diagnostic categories, but there was a highly significant association with the DSM-III classification 'major depressive episode with melancholia' (52%) in comparison with the ICD group 'manic-depressive illness-depressed' (29%).
(16) The DST may be useful as an adjunct to the diagnostic and monitoring process in primary depression with melancholia.
(17) In psychiatry cocaine was used--also on Freud's recommendation--as an euphoriant excitant in cases of melancholia, both physical and psychic exhaustion and of cachexia.
(18) Our findings support the descriptive validity of the DSM-III melancholia diagnostic category, although the DSM-III criteria are too conservative and include nonrelevant symptoms (e.g., diurnal variation, anorexia-weight loss) whilst excluding some important items (e.g., loss of energy, cognitive disorders).
(19) The thyrotropin (TSH) and prolactin (PRL) responses to TRH were studied in 15 female depressed patients with melancholia (nine unipolar, six bipolar) during an electroconvulsive therapeutic course.
(20) Non-suppression of cortisol after dexamethasone was associated with blunted TSH-responses only in melancholia.
Melancholy
Definition:
(n.) Depression of spirits; a gloomy state continuing a considerable time; deep dejection; gloominess.
(n.) Great and continued depression of spirits, amounting to mental unsoundness; melancholia.
(n.) Pensive maditation; serious thoughtfulness.
(n.) Ill nature.
(a.) Depressed in spirits; dejected; gloomy dismal.
(a.) Producing great evil and grief; causing dejection; calamitous; afflictive; as, a melancholy event.
(a.) Somewhat deranged in mind; having the jugment impaired.
(a.) Favorable to meditation; somber.
Example Sentences:
(1) One radio critic described Jacobs' late night Sunday show as a "tidying-up time, a time for wistfulness, melancholy, a recognition that there were once great things and great feelings in this world.
(2) And melancholy is not the only thing that links Haigh’s work.
(3) Melancholy originally had another meaning from the present one.
(4) the agitated type of involutional melancholy occurred twice as often in Canada as in Hungary, the apathetic cases were rarer in Canada, and the illness began earlier among Canadian women.
(5) Thus New Zealand, like other countries, may be entering an age of melancholy.
(6) English explanations stressed religious aspects and a relationship to melancholy.
(7) I too was attracted to the paintings of De Chirico and Delvaux, with their dreamplaces – empty, melancholy cities, abandoned temples, broken statues, shadows, exaggerated perspectives.
(8) Earlier this week in Janesville, where post-industrial melancholy is evident in a closed car plant and eerily quiet downtown, House speaker Paul Ryan crushed a Trump-style challenger in a congressional primary.
(9) There was always a rueful melancholy, stiffened by irony and leavened by humour about him.
(10) Song of the summer was Waterloo Sunset by the Kinks, with its odd blend of keening melancholy and positivism.
(11) Resorting to a series of Ted the swordsman scenes which may merely be the lurid fantasies of the heroine, director Christine Jeffs never makes it clear whether Hughes was a rampaging philanderer whose sexual conquests and general obliviousness to Plath's mounting depression led to her demise, or a man driven into other women's arms by his wife's chronic melancholy - perhaps the most time-honoured excuse of the inveterate tomcat - or both.
(12) "Oh, if one of Dostoevsky's novels, whose black melancholy is regarded with such indulgent admiration, were signed with the name of Goncourt, what a slating it would get all along the line."
(13) It's a melancholy fate for any writer to become an eponym for all that he despised, but that is what happened to George Orwell, whose memory is routinely abused in unthinking uses of the adjective "Orwellian".
(14) As the lead singer with the Walker Brothers, he enjoyed a number of melancholy hits with songs such as The Sun Ain't Gonna Shine Anymore, My Ship Is Coming In, No Regrets.
(15) The leading role is infinitely variable: as Oscar Wilde said , "There are as many Hamlets as there are melancholies."
(16) In the right light and with the right song playing on the radio, there is a certain melancholy charm to this bleak highway with its unfolding panorama of wind turbines and electricity pylons stretching to the horizon.
(17) On the contrary: Sørens incomparable melancholy, mental agony and anxiety (fear or anguish) forced the faith, existing independently of them, in a radical refining.
(18) There’s a magnificent melancholy about him, this shadowy figure performing an act of unrequited love.
(19) Closer is a melancholy piece but it is also laugh-out-loud funny, often, as in the very best drama, at moments of starkest pain.
(20) Research is needed to determine whether youth will be predisposed to further depressive episodes and, if so, will we be entering a new age of melancholy?