(a.) Given to melancholy; depressed; melancholy; dejected; unhappy.
(n.) One affected with a gloomy state of mind.
(n.) A gloomy state of mind; melancholy.
Example Sentences:
(1) The authors took multiple serum samples for measurement of melatonin between 4:30 p.m. and 7:30 a.m. in seven male depressed patients with melancholia and five healthy male control subjects and found that melancholic patients had a significantly lower rise of melatonin.
(2) With the Extracted Criteria, initial insomnia, early waking, anorexia, weight loss, loss of libido, and worsened mood in the morning were all significantly more common in melancholia than in non-melancholic depression, while increased appetite was more common in non-melancholia.
(3) Patients with a past history of major melancholic depression or severe agoraphobia had similar binding parameters as panic disorder patients without a history of depression or severe agoraphobia.
(4) Every episode was diagnosed cross-sectionally as schizophrenic, melancholic, manic, manic-depressive mixed, schizodepressive, schizomanic or schizomanic-depressive mixed.
(5) Lower fT3 levels were also observed in melancholic depressed patients when compared with nonmelancholic depressed patients or when compared with normal control subjects.
(6) Melancholic episode: according to "Major Depression, Melancholic Type" of DSM-III-R. Manic episode: according to the criteria of DSM-III, slightly modified.
(7) Controlling for baseline biological, clinical, and demographic factors eliminated the higher prolactin response in the melancholic and psychotic patients, attenuated the blunted GH response in the unipolar patients, and revealed a blunted GH response in the melancholic patients.
(8) Occasionally certain behavioural styles and symptoms can be seen in melancholics which are difficult to classify as hysterical or pseudohysterical.
(9) However, when subjects were stratified based upon the presence or absence of DSM III-R melancholic features, the melancholic depressives showed little change in weekly depression ratings compared to patients without melancholic symptoms (p less than 0.001).
(10) Sixty-four percent of buspirone patients and 50% of placebo patients were melancholic; 64% of buspirone patients and 74% of placebo patients discontinued treatment before the end of the study.
(11) To explore whether abnormal CCK secretion during feeding may be related to pathophysiological mechanisms in disorders associated with appetite abnormalities, we report here studies of the plasma CCK response to a test meal in patients with bulimia nervosa, as well as seasonal (hyperphagic) and melancholic (anorexic) depression.
(12) A tendency in the opposite direction of the thyroxine values was found in bipolar (melancholic) patients.
(13) The results suggest that the 'depressive attributional style' may be specific to melancholic patients, and underline the importance of studying well-defined diagnostic subgroups.
(14) The test may have power in differentiating severe melancholic depression, mania, or acute psychosis from chronic psychosis (87% specificity) or dysthymia (77% specificity).
(15) In addition, when patients with more severe, melancholic, subtype of depression were examined, adinazolam was also as effective as imipramine.
(16) In the depressed group, irritability and DSM-III-R melancholic type predicted 40% or the variance of stage 4 increment after ritanserin, as assessed by stepwise multiple regression.
(17) In conditions of conflict between probability and value of reinforcement the dogs manifested two opposite strategies of behaviour: orientation to highly probable events (choleric and phlegmatic) and to low-probable events (sanguinic and melancholic) what is connected with individual properties of functioning and the character of interaction of four brain structures (frontal cortex, hippocampus, hypothalamus, amygdala).
(18) The sensitivity of the DST (rate of a positive outcome, or nonsuppression of cortisol) in major depression is modest (about 40%-50%) but is higher (about 60%-70%) in very severe, especially psychotic, affective disorders, including major depression with psychotic as well as melancholic features, mania, and schizoaffective disorder.
(19) Serotonin in platelet-free plasma and in platelets from melancholics was significantly reduced to 30% and 60% of their respective control values.
(20) Many wept, wiping tears off their faces as the melancholic tunes of the hymns reached them through loudspeakers.
Melancholy
Definition:
(n.) Depression of spirits; a gloomy state continuing a considerable time; deep dejection; gloominess.
(n.) Great and continued depression of spirits, amounting to mental unsoundness; melancholia.
(n.) Pensive maditation; serious thoughtfulness.
(n.) Ill nature.
(a.) Depressed in spirits; dejected; gloomy dismal.
(a.) Producing great evil and grief; causing dejection; calamitous; afflictive; as, a melancholy event.
(a.) Somewhat deranged in mind; having the jugment impaired.
(a.) Favorable to meditation; somber.
Example Sentences:
(1) One radio critic described Jacobs' late night Sunday show as a "tidying-up time, a time for wistfulness, melancholy, a recognition that there were once great things and great feelings in this world.
(2) And melancholy is not the only thing that links Haigh’s work.
(3) Melancholy originally had another meaning from the present one.
(4) the agitated type of involutional melancholy occurred twice as often in Canada as in Hungary, the apathetic cases were rarer in Canada, and the illness began earlier among Canadian women.
(5) Thus New Zealand, like other countries, may be entering an age of melancholy.
(6) English explanations stressed religious aspects and a relationship to melancholy.
(7) I too was attracted to the paintings of De Chirico and Delvaux, with their dreamplaces – empty, melancholy cities, abandoned temples, broken statues, shadows, exaggerated perspectives.
(8) Earlier this week in Janesville, where post-industrial melancholy is evident in a closed car plant and eerily quiet downtown, House speaker Paul Ryan crushed a Trump-style challenger in a congressional primary.
(9) There was always a rueful melancholy, stiffened by irony and leavened by humour about him.
(10) Song of the summer was Waterloo Sunset by the Kinks, with its odd blend of keening melancholy and positivism.
(11) Resorting to a series of Ted the swordsman scenes which may merely be the lurid fantasies of the heroine, director Christine Jeffs never makes it clear whether Hughes was a rampaging philanderer whose sexual conquests and general obliviousness to Plath's mounting depression led to her demise, or a man driven into other women's arms by his wife's chronic melancholy - perhaps the most time-honoured excuse of the inveterate tomcat - or both.
(12) "Oh, if one of Dostoevsky's novels, whose black melancholy is regarded with such indulgent admiration, were signed with the name of Goncourt, what a slating it would get all along the line."
(13) It's a melancholy fate for any writer to become an eponym for all that he despised, but that is what happened to George Orwell, whose memory is routinely abused in unthinking uses of the adjective "Orwellian".
(14) As the lead singer with the Walker Brothers, he enjoyed a number of melancholy hits with songs such as The Sun Ain't Gonna Shine Anymore, My Ship Is Coming In, No Regrets.
(15) The leading role is infinitely variable: as Oscar Wilde said , "There are as many Hamlets as there are melancholies."
(16) In the right light and with the right song playing on the radio, there is a certain melancholy charm to this bleak highway with its unfolding panorama of wind turbines and electricity pylons stretching to the horizon.
(17) On the contrary: Sørens incomparable melancholy, mental agony and anxiety (fear or anguish) forced the faith, existing independently of them, in a radical refining.
(18) There’s a magnificent melancholy about him, this shadowy figure performing an act of unrequited love.
(19) Closer is a melancholy piece but it is also laugh-out-loud funny, often, as in the very best drama, at moments of starkest pain.
(20) Research is needed to determine whether youth will be predisposed to further depressive episodes and, if so, will we be entering a new age of melancholy?