(a.) Given to melancholy; depressed; melancholy; dejected; unhappy.
(n.) One affected with a gloomy state of mind.
(n.) A gloomy state of mind; melancholy.
Example Sentences:
(1) The authors took multiple serum samples for measurement of melatonin between 4:30 p.m. and 7:30 a.m. in seven male depressed patients with melancholia and five healthy male control subjects and found that melancholic patients had a significantly lower rise of melatonin.
(2) With the Extracted Criteria, initial insomnia, early waking, anorexia, weight loss, loss of libido, and worsened mood in the morning were all significantly more common in melancholia than in non-melancholic depression, while increased appetite was more common in non-melancholia.
(3) Patients with a past history of major melancholic depression or severe agoraphobia had similar binding parameters as panic disorder patients without a history of depression or severe agoraphobia.
(4) Every episode was diagnosed cross-sectionally as schizophrenic, melancholic, manic, manic-depressive mixed, schizodepressive, schizomanic or schizomanic-depressive mixed.
(5) Lower fT3 levels were also observed in melancholic depressed patients when compared with nonmelancholic depressed patients or when compared with normal control subjects.
(6) Melancholic episode: according to "Major Depression, Melancholic Type" of DSM-III-R. Manic episode: according to the criteria of DSM-III, slightly modified.
(7) Controlling for baseline biological, clinical, and demographic factors eliminated the higher prolactin response in the melancholic and psychotic patients, attenuated the blunted GH response in the unipolar patients, and revealed a blunted GH response in the melancholic patients.
(8) Occasionally certain behavioural styles and symptoms can be seen in melancholics which are difficult to classify as hysterical or pseudohysterical.
(9) However, when subjects were stratified based upon the presence or absence of DSM III-R melancholic features, the melancholic depressives showed little change in weekly depression ratings compared to patients without melancholic symptoms (p less than 0.001).
(10) Sixty-four percent of buspirone patients and 50% of placebo patients were melancholic; 64% of buspirone patients and 74% of placebo patients discontinued treatment before the end of the study.
(11) To explore whether abnormal CCK secretion during feeding may be related to pathophysiological mechanisms in disorders associated with appetite abnormalities, we report here studies of the plasma CCK response to a test meal in patients with bulimia nervosa, as well as seasonal (hyperphagic) and melancholic (anorexic) depression.
(12) A tendency in the opposite direction of the thyroxine values was found in bipolar (melancholic) patients.
(13) The results suggest that the 'depressive attributional style' may be specific to melancholic patients, and underline the importance of studying well-defined diagnostic subgroups.
(14) The test may have power in differentiating severe melancholic depression, mania, or acute psychosis from chronic psychosis (87% specificity) or dysthymia (77% specificity).
(15) In addition, when patients with more severe, melancholic, subtype of depression were examined, adinazolam was also as effective as imipramine.
(16) In the depressed group, irritability and DSM-III-R melancholic type predicted 40% or the variance of stage 4 increment after ritanserin, as assessed by stepwise multiple regression.
(17) In conditions of conflict between probability and value of reinforcement the dogs manifested two opposite strategies of behaviour: orientation to highly probable events (choleric and phlegmatic) and to low-probable events (sanguinic and melancholic) what is connected with individual properties of functioning and the character of interaction of four brain structures (frontal cortex, hippocampus, hypothalamus, amygdala).
(18) The sensitivity of the DST (rate of a positive outcome, or nonsuppression of cortisol) in major depression is modest (about 40%-50%) but is higher (about 60%-70%) in very severe, especially psychotic, affective disorders, including major depression with psychotic as well as melancholic features, mania, and schizoaffective disorder.
(19) Serotonin in platelet-free plasma and in platelets from melancholics was significantly reduced to 30% and 60% of their respective control values.
(20) Many wept, wiping tears off their faces as the melancholic tunes of the hymns reached them through loudspeakers.
Sanguine
Definition:
(a.) Having the color of blood; red.
(a.) Characterized by abundance and active circulation of blood; as, a sanguine bodily temperament.
(a.) Warm; ardent; as, a sanguine temper.
(a.) Anticipating the best; not desponding; confident; full of hope; as, sanguine of success.
(n.) Blood color; red.
(n.) Anything of a blood-red color, as cloth.
(n.) Bloodstone.
(n.) Red crayon. See the Note under Crayon, 1.
(v. t.) To stain with blood; to impart the color of blood to; to ensanguine.
Example Sentences:
(1) The Rt Rev Stephen Lowe, the Bishop of Hulme, who speaks for the Anglican church on urban life and faith, is less sanguine.
(2) Ministers are sanguine, expecting the controversy to die down once the bill becomes law, even if they are concerned at the way in which the rightwing commentariat has lined up against the bill.
(3) The article points out the possibilities and limitations of combining a) ascending phlebography of the leg and pelvis with peripheral venous pressure measurement (phlebodynamometry) and b) visualisation of the veins of the pelvis and vena cava inferior with central sanguinous venous pressure measurement (CP).
(4) Davis is sanguine about her occasionally fraught on-set encounters: "It's always an act of faith.
(5) Trade ministers, much lower down the pecking order, are more sanguine.
(6) The horses had stertorous breathing (n = 4) or intermittently sanguineous nasal discharge (n = 7).
(7) The initially sanguine expectations regarding the practical use of recombinant DNA research, for instance in the production of biologically important substances by bacteria, will therefore possibly not be realized at short notice.
(8) The sera from 2.028 blood donors were screened by all those techniques, as well as 105 known sera, used as references (87 HBS antigen positive sera with different titers, 18 HBS antigen negative sera) and coming from 4 origins: NIH-Bethesda, Centre National de Transfusion Sanguine, Paris; Hôpital de la Pitié-Salpêtrière, Paris; Hôpital Broussais, Paris.
(9) Fellow goalkeeper Tim Howard chimed in after the first US practice on the field to note that the grass comes in trays and that it “kind of jells together” to create “spots on the field that may tear up easily.” Clint Dempsey was fairly sanguine though — noting that while the ball may not bounce as much on this surface, that with the field being watered well “the ball will be moving quickly —which is important — and rolling true.” Let’s hope that the turf becomes a footnote in the game.
(10) In conditions of conflict between probability and value of reinforcement the dogs manifested two opposite strategies of behaviour: orientation to highly probable events (choleric and phlegmatic) and to low-probable events (sanguinic and melancholic) what is connected with individual properties of functioning and the character of interaction of four brain structures (frontal cortex, hippocampus, hypothalamus, amygdala).
(11) Cooze and the trust’s chairman, Phil Sumbler, say they knew the other shareholders would sell at some point and are sanguine about them making so much money.
(12) We need to keep cool heads as the market heats up.” Carney has been less sanguine over the state of Britain’s economy and earlier this week sent clear hints to financial markets that interest rates would be held at their record low of 0.5% for many months to come against the backdrop of a weaker world economy and a slowdown in the UK.
(13) Weaknesses are being exploited by firms to reduce their tax burdens.” While the proposed new rules could run into opposition from national EU governments that have to endorse the package, Moscovici sounded sanguine that there would be quick approval, enabling the mandatory and automatic exchange of information on tax rulings to come into effect by the end of next year.
(14) David can afford to be sanguine about his brother's choice of career, however, because he remains the more senior figure after making Question Time his own.
(15) Outside Byzantium Café, Saki, who is 72 and remembers the declaration of Cypriot independence ("You British knew what was going to happen"), is relatively sanguine.
(16) Although he couldn’t be described as sanguine about the reality of representing himself – “I get minor panic attacks just being in the same room as my ex” – he does believe it’s possible to do a decent job on your own behalf in court.
(17) The result is that, once again, the US and Britain have persuaded themselves of an ambitious course of action – weakening or even breaking the Putin-Assad link – the results of which other allies are less sanguine about.
(18) Personally I thought the Gomez take (cited in an mlssoccer.com story ) was about the most sanguine on it: I love it – I love it.
(19) Watery, serous, serosanguineous, and sanguineous discharges are surgically significant; while they are most often caused by intraductal papillomas or fibrocystic disease, they can be due to cancer or a precancerous mastopathy.
(20) Matthew Taylor, the former chief adviser on strategy to Tony Blair, is more sanguine about the chances of making the pitch "Brown in adversity".