What's the difference between melanism and melanosis?
Melanism
Definition:
(n.) An undue development of dark-colored pigment in the skin or its appendages; -- the opposite of albinism.
(n.) A disease; black jaundice. See Mel/na.
Example Sentences:
(1) In agreement with the InsP3 assays, phorbol ester (TPA) has no effect on melanization, tyrosinase activity or cell proliferation.
(2) These skins preserve the aspects and behaviour of normal human skin but after 1 month they have a heavy melanic hyperpigmentation.
(3) The skin is heavily pigmented with the epidermis, pilary canals, and the outer cell layer of the apocrine duct richly melanized.
(4) A ventrally localized melanization inhibiting factor (MIF) has been suggested to play an important role in the establishment of the dorsal-ventral pigment pattern in Xenopus laevis [Fukuzawa and Ide:Dev.
(5) The processes of melanosome maturation in the late-melanizing goldfish are evident from these observations.
(6) Melanin granules inside keratinocytes were fully melanized.
(7) Melanization in vivo, and in vitro, due to a polyphenoloxidase released by the blood cells, was stimulated by the presence of the fungal cell wall surface.
(8) The endogenous norepinephrine level was increased in eyes with melanic pigments and the exogenous amine uptake was decreased.
(9) The data suggest that host endocrines are involved in the encapsulation and melanization reactions of the larvae, but the nature of the involvement is not known.
(10) These findings suggest that glutathione provides a new situation of interrupted melanogenesis in which melanization cannot proceed despite complete formation of melanosome matrix structure and a lack of inhibition of cellular metabolisms including protein glycosylation.
(11) Conidiogenous cells in both species developed melanin only within the lowermost part of the lateral walls while the other cells of the conidium were uniformly melanized around the circumference of the cell; melanin in these cells being deposited within, at least, half the width of the cell wall.
(12) These changes may indicate the gradual melanization of the lipopigments due to auto-oxidation of catecholamines.
(13) Depending on the dose or period of feeding, symptoms were cuticular melanization, swellings in intersegmental regions, cuticular lesions, rupture of the body wall, and death.
(14) Intracellular melanization, a defense or an immune response in the thoracic muscle cells, was investigated in a refractory strain of Anopheles quadrimaculatus infected with larvae of Brugia malayi.
(15) Difficulty encountered in resolving grains of exposed photographic emulsion in autoradiographs of the densely melanized retinal pigment epithelium was solved by using epi-polarized or incident light microscopy.
(16) Inhibition of tyrosine hydroxylase with alpha-methyl-p-tyrosine retarded growth and prevented melanization of limb regenerate in adult newts (Triturus cristatus).
(17) sinensis was 72.3%; the percentage of melanized microfilariae in young Cx.
(18) It is suggested that the surface of the parasite may have inhibitors against enzyme systems causing melanization.
(19) During melanization, oxidation products of tyrosine are generated which are toxic to the cells.
(20) The melanization response of adult female Aedes aegypti (black-eyed Liverpool strain) against intrathoracically inoculated Dirofilaria immitis microfilariae (mff) was assessed with transmission electron microscopy.
Melanosis
Definition:
() The morbid deposition of black matter, often of a malignant character, causing pigmented tumors.
Example Sentences:
(1) Penile melanosis shares clinical and microscopic features with Laugier-Hunziker syndrome of the buccal mucosa and vulvovaginal melanosis.
(2) Seven cases of primary acquired melanosis were studied; one (33%) of three with atypia was HMB-45 positive, as were two (50%) of four without atypia.
(3) First, generalized melanosis is a rare complication in macrophages of skin and other areas.
(4) We have been freezing proliferative melanosis with the aid of a cryoprobe.
(5) Proptosis and ptosis, caused by a large orbital mass that was excised and determined to be malignant melanoma, developed in a 4-year-old girl with congenital neurocutaneous melanosis (multiple large or giant cutaneous nevi associated with abnormal leptomeningeal pigmentation).
(6) To our knowledge, this is the first reported case who has developed generalized skin melanosis and melanuria in its terminal stage.
(7) An otherwise normally developed child who had this hamartoma at birth is described in an attempt to clarify the relationship between pilar smooth-muscle hamartomas and Becker's melanosis.
(8) Primary acquired melanosis (PAM), a disease that affects mostly middle-aged white patients, is predominantly a proliferative condition of the melanocytes that normally populate the conjunctival epithelium.
(9) This concept of origin is proposed to apply to the Schimmelpenning-Feuerstein-Mims syndrome, the McCune-Albright syndrome, the Klippel-Trenaunay syndrome, the Sturge-Weber syndrome, and neurocutaneous melanosis.
(10) Becker's melanosis is an uncommon condition characterized by hypertrichosis, hyperpigmentation of the epidermis, dermal melanophages and absence of nevus cells.
(11) In patients with unilateral melanosis the blue, unaffected eye may also develop a melanoma.
(12) Primary malignant melanoma is an unusual neoplasm in the urinary bladder that is infrequently found in association with melanosis.
(13) An infant had a giant congenital nevus, neurocutaneous melanosis (NCM), and a Dandy-Walker malformation of the brain.
(14) Other benign pigmented lesions include lentigines, melanosis, postinflammatory hyperpigmentation, seborrheic keratoses, and warts.
(15) A case of neurocutaneous melanosis in a 15 year old male is described.
(16) The terms: borderline malignant melanoma or lesion, precancerous melanosis, active or activated nevus and atypical melanocytic hyperplasia should be abandoned.
(17) Their numbers and size were greatly increased in specimens of colon from patients with melanosis coli.
(18) Thirty five cases of neurocutaneous melanosis associated with or without malignant melanoma have been reported in Japan.
(19) Among 1072 rectoscopies we found 100 patients (9,3%) with melanosis coli.
(20) A case is presented in which a patient with a well-differentiated adenocarcinoma showed high gallium concentration in the segment with melanosis coli proximal to the obstruction.