What's the difference between menopause and perimenopause?
Menopause
Definition:
(n.) The period of natural cessation of menstruation. See Change of life, under Change.
Example Sentences:
(1) Osteoporosis and its treatment have attracted much attention in recent years, especially since the widespread recognition of its association with the menopause.
(2) Today the physician who treats women with emotional problems during menopause cannot function solely as a psychotherapist; he must deal with both their soma and psyche.
(3) The difference in the timing of the change in FSH and LH concentrations was related not only to chronological age but also to the number of years before the menopause.
(4) Women in the late pre-menopausal group who were clinically depressed had significantly higher levels of TSH and triiodothyronine than other subjects.
(5) A comparative evaluation of these data suggest that hormone independent cells are present in the cervical crypts of late menopause women and that a cyclic change of hormone dependent cells may occur in fertile women, analogous to the cyclic changes of endometrial mucosa.
(6) In short term clinical studies, the beneficial effects of transdermal estradiol on plasma gonadotrophins, maturation of the vaginal epithelium, metabolic parameters of bone resorption and menopausal symptoms (hot flushes, sleep disturbance, genitourinary discomfort and mood alteration) appear to be comparable to those of oral and subcutaneous estrogens, while the undesirable effects of oral estrogens on hepatic metabolism are avoided.
(7) The relationships between the menopause and risk factors for ischaemic heart disease are complex, which may be one reason for the contradictory results when relating menopausal age to the incidence of ischaemic heart disease.
(8) The modifying effect of estrogen receptor status on the relation of obesity to node involvement was apparent in pre- and post-menopausal women.
(9) The gonadally unresponsive patients had either pituitary tumours or premature menopause.
(10) Quantitative variation of the lysosomes in the epithelium of the human uterine tube in the menstrual cycle and in post-menopausal period.
(11) In contrast, none of 16 women who had reached menopause and only two of 21 men required oral absorption of dietary or prescribed iron for the amount of blood iron donated.
(12) To determine if menopausal status influenced the response to exercise, we analyzed the difference between groups for premenopausal and postmenopausal subjects separately.
(13) In pre-menopausal women no association has been found between increased height and weight as risk factors for breast cancer.
(14) Among breast cancer women, PRL increase was irrespective of the type of surgery, the histology of the tumor and the menopausal status.
(15) The same two estrogens were given to women with natural menopause, along with utrogestan, a micronized progesterone.
(16) It is highly probable that the menopause, spontaneous or above all artificially induced, is a cardiovascular risk factor.
(17) It is always purified on Sephadex G-100 immediately before addition to the RIA and in this manner it may be used for up to 2 month after labeling when kept at --20 degrees C. Curves obtained at different dilutions of the H-FSH Standard, carried out with phosphosaline buffer, pH 7.4-7.8 (PBS) containing 1 % human serum albumin, or with horse plasma, of with PBS containing 0,25 % serum from non-immune rabbits (RIA Buffer) have been compared iwth those abtained by serial dilutions of sera from post-menopausal with these diluents.
(18) Three women in generation IV have developed pre-menopausal breast cancer.
(19) None of the variables examined emerged as being significantly associated with PA when data from pre-menopausal patients were used.
(20) Estrogen receptors are more frequently found in post-menopausal women than in women who are still menstruating.
Perimenopause
Definition:
Example Sentences:
(1) No significant correlations were noted between serum hormone levels during the perimenopausal period.
(2) This altered pattern of estrogen binding in perimenopausal tumors likely results from the hormonal changes of the menopausal and late premenopausal years.
(3) 147 stage II pre- and perimenopausal breast cancer patients were treated with cyclophosphamide-methotrexate-5-fluorouracil (CMF)- based adjuvant regimens.
(4) The four women with normal luteal function had castrate estrogen levels following regression of the corpus luteum, whereas one woman with an abnormal luteal phase and perimenopausal levels of gonadotropins had an agonistic response.
(5) The changes in serum concentrations of luteinizing hormone (LH), follicle-stimulating hormone (FSH), estradiol (E2), and progesterone (P) during menstrual cycles in a group of perimenopausal women were compared with the findings in young normal women.
(6) When comparing this type of tumors, named locally advanced cancer with inflammatory component, to other locally advanced cancers, some remarkable differences are found: there is a preponderance of younger patients, premenopausal or perimenopausal, with a greater percentage of poorly differentiated tumors and negative estrogen receptors.
(7) Controversy surrounds the optimal use of estrogen replacement therapy (ERT) for the management of vasomotor instability and other perimenopausal symptoms.
(8) The net resource costs and net health benefits of treating perimenopausal women with hormone replacement therapy were evaluated within the framework of cost-effectiveness analysis.
(9) The principal means of evaluating perimenopausal bleeding is endometrial biopsy performed in the office.
(10) All the turnover variables were measured in a group of perimenopausal women (n = 33).
(11) In the large group of patients with localized disease the association with radiation was obvious for all ages combined (irradiated RR = 3.0, not irradiated RR = 1.6), but not obvious among premenopausal (age less than 45 years) and perimenopausal (age 45-54 years) women at primary breast cancer until followed for 20 years.
(12) Sclerosing adenosis was most frequent in the perimenopausal period and had a weak association with family history of IBC.
(13) Forty-three perimenopausal women kept daily records of menstrual cycles and sexual activity.
(14) This case suggests that some perimenopausal women may respond to their own endogenous elevated gonadotropins as if they are taking ovulation-inducing drugs and may, as a consequence, form multiple follicles.
(15) Estriol (E3) and estradiol (E2) was given to 81 women with perimenopausal complaints.
(16) Epidemiologic studies have demonstrated an increase in complaints of depressed mood and other minor psychological changes from patients in the perimenopause.
(17) A perimenopausal woman presented with a calcific adnexal mass seen on abdominal radiography, surgical exploration revealed no gross evidence of metastatic disease.
(18) The exact mechanism for these totally different responses to leuprolide acetate in two perimenopausal women is not known.
(19) The literature concerning malignancy developing in extragonadal endometriosis has been reviewed and is summarized as follows: 1) 45 cases have been compiled, of which 32 were carcinomas and 13 sarcomas; 2) adenocarcinoma was the most common histologic type, although virtually every tumor of müllerian derivation has been described; 3) the typical patient was nulliparous and perimenopausal; 4) the rectovaginal septum was the most common site, and in general the frequency of malignancy in a given site parallels the frequency of endometriosis in that location; 5) simultaneous tumors of the uterus or ovary were present in seven cases (15%); 6) prognosis appeared affected by site and histologic type; 7) a history of prior pelvic irradiation to effect castration was present in three (9%) of the patients with adenocarcinoma; and 8) four (12%) of the patients with adenocarcinoma were subjected to exogenous estrogens or estrogen-secreting ovarian tumors.
(20) Many of these women are now perimenopausal and therefore entering the age of risk for ovarian neoplasia.