(1) The degree of increase in Meth responsiveness elicited by the initial provocation is a major factor in determining the airway response to a subsequent HS challenge.
(2) Enhanced H2O2 generation was observed in PMP activated by long-term stimulation followed by triggering with PMA, but not observed by triggering with Meth A cells.
(3) Known as crank, crystal, ice, crystal meth, and speed, MAP can be produced easily from ephedrine, and it is widely available.
(4) You are hunting for signs of the assembly of injuries - a broken nose, knocked-out teeth, fractured eye socket - incurred by falling face-first down a fire escape in Michigan while high on crystal meth, crack cocaine and cheap wine.
(5) The interaction between the MetR activator protein and the S. typhimurium metH control region was investigated.
(6) The Dyn system associated with the nucleus accumbens responded in a similar manner in that MK801 totally blocked the METH-induced increases; moreover, NMDA elevated the Dyn content in this structure.
(7) The vitamin B12 (B12)-mediated repression of the metE gene in Escherichia coli and Salmonella typhimurium requires the B12-dependent transmethylase, the metH gene product.
(8) OK-432 at a dose of 0.1, 1 or 10 KE was administered orally every 3 days or every other day for 30 days to subcutaneously Meth A tumor-inoculated mice.
(9) Like METH, single or multiple doses of either drug caused marked reductions in both tryptophan hydroxylase (TPH) activity and concentrations of 5-hydroxytryptamine (5HT) and 5-hydroxyindoleacetic acid (5HIAA) in several brain regions.
(10) As soon as I called them and was like, 'Hey guys, it's OK, I'm not smoking meth or anything,' it was OK." He adds, frowning: "I don't really know why it happened… My girlfriend told me everyone had been saying, [he puts on a sulky voice] 'Man, Mac's shows aren't crazy any more.'
(11) Tolerance in some endocrine systems appears to be quite long-lasting, as CS, TSH and PRL responses to METH challenge were still decreased 3 weeks after withdrawal from the ID regimen.
(12) The chief executive is pinning early hopes on Breaking Bad, a gritty US drama in which a chemistry teacher with terminal cancer sets up a crystal meth lab, which was barely noticed when it aired on 5USA, although for all its merits it might not exactly be classified as family entertainment.
(13) Furthermore, F-drugs could be utilized to probe the microenvironmental pH in Meth-A cells, in which the drug was located by the ratio of fluorescent intensities at 450 and 490 nm.
(14) The induction of IFN-gamma production by in vivo tumor-sensitized T cells is tumor specific, in that spleen cells from mice immunized against Meth A fibrosarcoma can produce IFN in response to irradiated Meth A cells but not in response to another syngeneic tumor M109 lung carcinoma.
(15) Splenic cells obtained from Meth-A inoculated mice which received combination therapy were not only NK-sensitive YAC-1 and LAK-sensitive EL-4 cells, but also NK-resistant Meth-A cells, as shown in a 4-h 51Cr-release assay.
(16) In this investigation, primary myocardial cell cultures were established from 3-5-day-old Sprague-Dawley rats to describe the adverse effects of Coc and Meth on the myocardium.
(17) During a raid in 2013 on a village in Guangdong province nicknamed “China’s number one drug village”, police closed dozens of secret drug labs producing meth and ketamine and confiscated at least three tonnes of drugs worth about £142m.
(18) Pharmaceutical dosage was set at approximately 30% of the increased life span (ILS) for Meth-A.
(19) No excellent antitumor effects of three platinum complexes were observed against Lewis lung carcinoma and B16 melanoma implanted s.c. even at triple injection every other day, and no effect was obtained against Meth-A fibrosarcoma under similar conditions.
(20) Eight metH mutants in Salmonella typhimurium with closely linked sites of mutation which could grow only on methionine were isolated from a metE mutant deficient in N(5)-methyltetrahydropteroyltriglutamate-homocysteine transmethylase; their deficiency in cobalamin-dependent N(5)-methyltetrahydrofolate-homocysteine transmethylase was supported by the results of enzyme studies of one of them.
Methamphetamine
Definition:
Example Sentences:
(1) Methamphetamine abuse is increasing and methamphetamine is second only to alcohol as a positive finding in cases submitted to the San Diego Sheriff's Crime Laboratory.
(2) Aggressive behavior was evoked by introducing a group-housed male mouse (intruder) into the home cage of the isolated or nonisolated mouse (resident).d-Amphetamine, methamphetamine, methylphenidate, cocaine, and L-dopa decreased attack and threat behavior by resident mice, the isolates requiring 2--4 times higher drug doses for the antiaggressive effects than the nonisolates, d-Amphetamine, methamphetamine, and methylphenidate caused intruder mice to be more frequently attacked by their non-treated resident opponents, to escape more often, to assume the defensive upright posture less, and to move about more often.
(3) 1-Methyl,1'-hexanoic acid-4,4'-bi-pyridinium, 4-amino-D,L-phenylalanine-diazo-coupled diquat, p-amino-methamphetamine as haptens were synthesized and coupled to bovine serum albumin (BSA) directly or to BSA via glutaraldehyde, and an antigen of MT was prepared by binding MT to BSA with the Mannich reaction.
(4) For a decade, relatively little methamphetamine was submitted to street-drug analytical labs.
(5) ), given 15 min before each dose of methamphetamine, totally prevented the methamphetamine-induced loss of tyrosine hydroxylase activity and partly prevented the loss of dopamine.
(6) Effects of dose, route of administration, and sex and strain differences on the metabolism of methamphetamine in vivo were investigated in rats.
(7) After ingesting 3,4-methylene-dioxy-methamphetamine (MDMA) and the monoamine oxidase (MAO) inhibitor phenelzine, a 50 year old male developed marked hypertension, diaphoresis, altered mental status, and hypertonicity lasting 5-6 hours.
(8) The method has been applied to the analysis of urine samples from monkeys singly and repeatedly treated with methamphetamine.
(9) After a 7-day abstinence period, a challenge test with methamphetamine alone revealed supersensitivity of methamphetamine-sensitized rats to subsequent methamphetamine, whereas rats pretreated with repeated methamphetamine in combination with BMY 14802 exhibited no difference in the intensity of stereotypy from rats pretreated with repeated saline.
(10) The report by University of New South Wales (UNSW) researchers examined available data on drug-related deaths, hospital admissions, and treatment services, and also found that within methamphetamine related deaths, the drug was the underlying cause in 23%.
(11) The effects of quinidine and cimetidine on methamphetamine-induced stereotyped behavior were studied in rats.
(12) Both the presence of arterial inflammation and increased blood pressure caused by sympathomimetic action of methamphetamine are probably the important factors in the occurrence of intracranial hemorrhage associated with methamphetamine.
(13) Remarkable changes in the circadian activity rhythm of rats were observed when they were chronically treated with methamphetamine dissolved in drinking water.
(14) After grafting, however, DOPAC and HVA restored to control levels and responded to methamphetamine with decreases as was observed in control animals.
(15) Compared with placebo and methamphetamine, diphenhydramine caused subjects no experience geophysical time as passing more slowly, but the drug had no significant effects on the visual search or divided-attention tasks.
(16) The present results suggest that the induction of hypothalamic IL-1 beta mRNA by methamphetamine is mediated by beta-adrenoceptors in the brain.
(17) This study proposes a method capable of separating the pharmacodynamic from the pharmacokinetic component in the methamphetamine (MA) hyperactivity potentiation induced by antidepressants.
(18) The effects of 5-HT3 receptor antagonists, MDL72222 and ICS205-930, on cocaine- and methamphetamine-induced place preference were examined.
(19) YM-08050 was more potent than either HPD or CPZ in inhibitory effects on a variety of behaviors such as apomorphine-induced stereotypes behavior and emesis, methamphetamine-induced stereotyped behavior, conditioned avoidance response and open field behavior.
(20) Bilateral injection of CCK-8 (1 microgram per side) into the nucleus caudatus significantly reduced the locomotor hyperactivity induced by methamphetamine.