(1) Methamphetamine abuse is increasing and methamphetamine is second only to alcohol as a positive finding in cases submitted to the San Diego Sheriff's Crime Laboratory.
(2) Aggressive behavior was evoked by introducing a group-housed male mouse (intruder) into the home cage of the isolated or nonisolated mouse (resident).d-Amphetamine, methamphetamine, methylphenidate, cocaine, and L-dopa decreased attack and threat behavior by resident mice, the isolates requiring 2--4 times higher drug doses for the antiaggressive effects than the nonisolates, d-Amphetamine, methamphetamine, and methylphenidate caused intruder mice to be more frequently attacked by their non-treated resident opponents, to escape more often, to assume the defensive upright posture less, and to move about more often.
(3) 1-Methyl,1'-hexanoic acid-4,4'-bi-pyridinium, 4-amino-D,L-phenylalanine-diazo-coupled diquat, p-amino-methamphetamine as haptens were synthesized and coupled to bovine serum albumin (BSA) directly or to BSA via glutaraldehyde, and an antigen of MT was prepared by binding MT to BSA with the Mannich reaction.
(4) For a decade, relatively little methamphetamine was submitted to street-drug analytical labs.
(5) ), given 15 min before each dose of methamphetamine, totally prevented the methamphetamine-induced loss of tyrosine hydroxylase activity and partly prevented the loss of dopamine.
(6) Effects of dose, route of administration, and sex and strain differences on the metabolism of methamphetamine in vivo were investigated in rats.
(7) After ingesting 3,4-methylene-dioxy-methamphetamine (MDMA) and the monoamine oxidase (MAO) inhibitor phenelzine, a 50 year old male developed marked hypertension, diaphoresis, altered mental status, and hypertonicity lasting 5-6 hours.
(8) The method has been applied to the analysis of urine samples from monkeys singly and repeatedly treated with methamphetamine.
(9) After a 7-day abstinence period, a challenge test with methamphetamine alone revealed supersensitivity of methamphetamine-sensitized rats to subsequent methamphetamine, whereas rats pretreated with repeated methamphetamine in combination with BMY 14802 exhibited no difference in the intensity of stereotypy from rats pretreated with repeated saline.
(10) The report by University of New South Wales (UNSW) researchers examined available data on drug-related deaths, hospital admissions, and treatment services, and also found that within methamphetamine related deaths, the drug was the underlying cause in 23%.
(11) The effects of quinidine and cimetidine on methamphetamine-induced stereotyped behavior were studied in rats.
(12) Both the presence of arterial inflammation and increased blood pressure caused by sympathomimetic action of methamphetamine are probably the important factors in the occurrence of intracranial hemorrhage associated with methamphetamine.
(13) Remarkable changes in the circadian activity rhythm of rats were observed when they were chronically treated with methamphetamine dissolved in drinking water.
(14) After grafting, however, DOPAC and HVA restored to control levels and responded to methamphetamine with decreases as was observed in control animals.
(15) Compared with placebo and methamphetamine, diphenhydramine caused subjects no experience geophysical time as passing more slowly, but the drug had no significant effects on the visual search or divided-attention tasks.
(16) The present results suggest that the induction of hypothalamic IL-1 beta mRNA by methamphetamine is mediated by beta-adrenoceptors in the brain.
(17) This study proposes a method capable of separating the pharmacodynamic from the pharmacokinetic component in the methamphetamine (MA) hyperactivity potentiation induced by antidepressants.
(18) The effects of 5-HT3 receptor antagonists, MDL72222 and ICS205-930, on cocaine- and methamphetamine-induced place preference were examined.
(19) YM-08050 was more potent than either HPD or CPZ in inhibitory effects on a variety of behaviors such as apomorphine-induced stereotypes behavior and emesis, methamphetamine-induced stereotyped behavior, conditioned avoidance response and open field behavior.
(20) Bilateral injection of CCK-8 (1 microgram per side) into the nucleus caudatus significantly reduced the locomotor hyperactivity induced by methamphetamine.
Tweak
Definition:
(v. t.) To pinch and pull with a sudden jerk and twist; to twitch; as, to tweak the nose.
(n.) A sharp pinch or jerk; a twist or twitch; as, a tweak of the nose.
(n.) Trouble; distress; tweag.
(n.) A prostitute.
Example Sentences:
(1) Bojan Krkic had been snuffed out in his central role for Stoke and Hughes’s tweaks would have paid off if Diouf’s finishing had been more incisive.
(2) Starting small, with oddly tweaked vocal samples and ominous-sounding piano, the first half is brilliantly brooding, to the point where the first chorus of “I love these streets but they weren’t meant for me to walk” arrives at the 45-second mark just as all the music drops away completely.
(3) That's likely to mean a tweak in set-up – most likely Vidal will play in more of an advanced role, with Silva adding extra ballast in behind him.
(4) Figures from the Halifax showing a 2.4% rise in prices in February could put pressure on the chancellor to announce tweaks to Help to Buy in next week's budget.
(5) And we will report back on how we are doing and we might have to tweak, but this is what we are aiming for."
(6) Once humans have gained "total mastery over morphological genetics", post-60,000 years from now, we'll be tweaking our children's DNA so that they're born with straight noses, regal lines and perfect facial symmetry.
(7) The Liverpool manager, Brendan Rodgers, secured Fabio Borini from Roma last week and is still hoping to tweak his squad before the new season, retaining interest in Fulham's Clint Dempsey and the Swansea City midfielder Joe Allen, and any money from Carroll's sale would bolster the funds at his disposal.
(8) "That essentially is just a group of people agreeing on tweaking things and making them a little bit different.
(9) The results are stunning and include precise measurements of the matter content of the universe and a tweak to the best estimate for its age.
(10) The Observer view on tax credit cuts | Observer editorial Read more “These are very significant changes and therefore I am sure the chancellor is keeping an open mind and will be looking to see whether any specific tweaks need to be made in the comprehensive spending review which takes place next month,” he said.
(11) It will need lots of tweaking to avoid annoying people – it's already being prodded to see whether it takes more or fewer clicks to reach the phone-dialer (more), and whether you can still set wallpaper (no, but your friends do with their picture – you may need to prune your friends).
(12) So let us tweak the question slightly and ask: what is the point of Jimmy Carr?
(13) The show's storylines were tweaked to take account of the new post-watershed slot.
(14) Osborne won limited support for "technical" tweaks to the draft legislation , although it appeared unlikely that Britain would make big gains in seeking to reverse the key points.
(15) The Department for Transport unveiled several tweaks to the first stage of the HS2 route to mollify opponents in the wealthy commuter belt north and west of London.
(16) To Geldof’s credit, he has said some of the lyrics will be tweaked slightly for this new version.
(17) She has been staying in the Y:Cube temporarily as a test to help the architects tweak the interior design.
(18) The engineers have put a brave face on the crash landings, tweaking navigation software, landing trajectories and other details based on each test.
(19) It may also offer tweaked devices to get around any injunction: "Samsung has already made some design changes to new products since the litigation first started more than a year ago," said Seo Won-seok, an analyst at Korea Investment & Securities.
(20) What they are prepared to do is tweak the existing doctrine," said Rebecca Johnson, the head of the Acronym Institute, a pro-disarmament pressure group.