(n.) A hydrocarbon radical, CH3, not existing alone but regarded as an essential residue of methane, and appearing as a component part of many derivatives; as, methyl alcohol, methyl ether, methyl amine, etc.
Example Sentences:
(1) Phospholipid methylation in human EGMs is distinctly different from that in rat EGMs (Hirata and Axelrod 1980) in that the human activity is not Mg++-dependent, and apparent methyltransferase I activity is located in the external membrane surface.
(2) Structure assignment of the isomeric immonium ions 5 and 6, generated via FAB from N-isobutyl glycine and N-methyl valine, can be achieved by their collision induced dissociation characteristics.
(3) Microionophoretically applied excitatory amino acids induced firing of extracellularly recorded single units in a tissue slice preparation of the mouse cochlear nucleus, and the similarly applied antagonist 2-amino-5-phosphonovalerate (2APV) was demonstrated to be a selective N-methyl-D-aspartate (NMDA) receptor antagonist.
(4) A novel bicyclic prostaglandin analogue, (1S)-[1 alpha,2 alpha(Z),3 alpha,4 alpha]-7-[3-[(hexylthio)methyl]-7- oxabicyclo [2.2.1]hept-2-yl]-5-heptenoic acid ((-)-10), and its cogeners were found to be potent antagonists at the TxA2 receptor.
(5) The enzyme was solubilized by Triton X-100 and purified approximately 480-fold by gel filtration and affinity chromatography on alanine methyl ketone-AH-Sepharose 4B.
(6) Glycosyl ceramide concentration was determined by gas-liquid chromatography of the trimethylsilyl ethers of the methyl glycosides.
(7) We have measured the antibody specificities to the two polysaccharides in sera from asymptomatic group C meningococcal carriers and vaccinated adults by a new enzyme-linked immunosorbent assay (ELISA) procedure using methylated human serum albumin for coating the group C polysaccharide onto microtiter plates.
(8) A new type of Escherichia coli mutant which shows increased sensitivity to methyl methane sulfonate but not to UV light or to gamma rays was isolated after mutagenesis with N-methyl-N'-nitro-N-nitrosoguanidine.
(9) The effect of S-adenosylhomocysteine on DNA methylation was examined, and it was found at equal molar concentrations of S-adenosylhomocysteine to to S-adenosylmethionine that DNA methylation was competitively inhibited 50%.
(10) Thermal stabilities (Tm's) of the hybrid between the 2'-O-methyl ribooligomer and the complementary ribooligomer and of the related hybrids are compared.
(11) Intoxicating concentrations of ethanol also inhibit excitatory synaptic transmission mediated by N-methyl-D-aspartate receptors in hippocampal slices from adult rodents.
(12) S-methyl-l-cysteine, 2-hydroxy-4-methiol butyric acid, S-adenosyl-l-methionine, and methionine peptides were the only compounds supporting growth, when substituted for methionine.
(13) Immunocytochemical analyses of the hippocampus demonstrated that alpha-amino-3-hydroxy-5-methyl-isoxazole-4-propionate receptor subunits are present in the cell bodies and dendrites of pyramidal cells.
(14) It was concluded that the detachment of the oxaloyl residue from oxaloacetate and its replacement by a proton proceed with inversion of configuration at the methylene group which becomes methyl during the hydrolysis.
(15) These products were identified to be epimers of 5,12(S)-dihydroxy-eicosatetraenoic acid methyl ester (5,12(S)-diHETE-Me) and epimers of 11,12-diHETE-Me.
(16) CCK-8 was acylated with the iodinated aryl azide derivatives, methyl-3-azido-4-hydroxy-5-[125I]iodobenzimidate and N-[4-(4'-azido-3'-[125I]iodophenylazo)benzoyl]-3-aminopropionyl-N- oxy- succinimide.
(17) Substitution of NaCl in the extracellular medium by sucrose, LiCl, or Na2SO4 had no effect on glutamate stimulation of [3H]dopamine release; however, release was inhibited when NaCl was replaced by choline chloride or N-methyl-D-glucamine HCl.
(18) Incubation of membrane with DL-Hcys alone (5 X 10(-5) M), the combination of both Ad (5 X 10(-5)) and DL-Hcys (5 X 10(-5)), or S-adenosyl-L-homocysteine (SAH) (1 X 10(-6)) strongly decreased the methyl ester formation.
(19) The 1-0-methylalduronic-acidmethylesters, obtained by the methanolysis of the polysaccharides, are reduced with boronhydrid to the corresponding methyl glycosides; there are split with acid to the aldoses, which are converted in pyridine with hydroxylamine to the aldoximes and than with acetic anhydride to the aldonitrilacetates, which can be separated by gaschromatography without difficulty.
(20) The effects of postnatal methyl mercury exposure on the ontogeny of renal and hepatic responsiveness to trophic stimuli were examined.
Quinaldine
Definition:
(n.) A colorless liquid of a slightly pungent odor, C9H6N.CH3, first obtained as a condensation product of aldehyde and aniline, and regarded as a derivative of quinoline; -- called also methyl quinoline.
Example Sentences:
(1) In addition, some quinaldine red may be present in the cytoplasm in an aggregated, ionically bound form.
(2) The following degradation products of quinaldine were isolated from the culture fluid and identified: 1H-4-oxoquinaldine, N-acetylisatic acid, N-acetylanthranilic acid, anthranilic acid, 3-hydroxy-N-acetylanthranilic acid and catechol.
(3) However, uptake as well as subsequent ionic binding of quinaldine red seems to be related to potential in an as yet undefined manner.
(4) A major aspect of the change is that in sodium-loaded cells, essentially all of the quinaldine red accumulated as the result of energization forms a strong bond with an anionic group.
(5) 4-(2'-, 4'-nitro- and 2',4'-dinitrobenzenesulfenamido)-quinaldines (I--III) as well as 2-(2'-,3'-nitro and 2',4'-dinitrobenzensulfenamido)-46-oimethylpyrimidines (IV--VI) were obtained.
(6) 2-Hydroxymethylquinoline and quinaldine are found in nonfresh greyhound urine as putrefactive bases.
(7) 2-aminomethylquinoline is excreted in fresh urine and two others, quinaldine and 2-hydroxymethylquinoline, are formed as the urine decays.
(8) The determination of dichloralantipyrine is based on the fact that it, as well as its major metabolite chloral hydrate, produces a blue color with quinaldine ethiodide.
(9) Solvent Yellow 33 (German: Rauchgelb) belongs to the groups of quinaldine dyes which are produced by condensing quinaldine and phthalic anhydride.
(10) The general characteristics of the cation employed, quinaldine red, closely paralleled those of other amphiphilic cations which have been used to measure membrane potential.
(11) The aggregates were estimated to contain at least five quinaldine red cations at or near van der Waals contact, and the presence of other molecules, such as phospholipids, could not be excluded.
(12) Quinaldine catabolism was investigated with the bacterial strain Arthrobacter sp., which is able to grow aerobically in a mineral salt medium with quinaldine as sole source of carbon, nitrogen and energy.
(13) Type A monoamine oxidase (MAO-A) in human placental mitochondria was competitively inhibited by naturally occurring substances, quinoline and quinaldine, using kynuramine as substrate.
(14) This binding is similar to that which occurs for the basal level of quinaldine red taken up in nonenergized cells.
(15) Uptake of the anesthetics tricaine methanesulfonate, benzocaine, Piscaine, and quinaldine is rapid because they are lipophilic.
(16) Production of 2-hydroxymethylquinoline or quinaldine is not arrested but merely retarded by preservation or refrigeration.
(17) The results show that membrane potential cannot be computed in a simple manner from the distribution of quinaldine red between cells and medium, assuming that the thermodynamic activity coefficient of cell-localized material is identical with that in dilute aqueous solution.
(18) The dithioacetic acid zwitterions were prepared from the base-catalyzed reaction of carbon disulfide with quinaldine and picoline methiodides, and the bis(methylthio) derivatives resulted from reaction with methyl iodide at room temperature.
(19) A method for the measurement of quinaldine and 2-hydroxymethylquinoline using gas chromatography is described.
(20) 2-Hydroxymethylquinoline forms in greyhound urine, if non-preserved, in three or four days at room temperature while quinaldine takes as much as 10 days longer to form.