(1) Acquired drug resistance to INH, RMP, and EMB can be demonstrated in M. kansasii, and SMX in combination with other agents chosen on the basis of MIC determinations are effective in the treatment of disease caused by RMP-resistant M. kansasii.
(2) From 1983 to 1986 more than 2000 non-penicillinase producing Neisseria gonorrhoeae from Amsterdam, The Hague and Rotterdam were auxotyped and screened for susceptibility to 10 antibiotics by MIC determination.
(3) MICs of cefazolin and cefoxitin were also measured for Escherichia coli.
(4) MICs of chlortetracycline were 8 to 16 times higher than MICs of the other tetracyclines.
(5) MICs for the tested molecules correlate strongly with their binding parameters.
(6) After that during 14 days the concentration of gentamicin in the implantation zone maintained at the level higher than its MIC for the main pathogens of wound infections.
(7) The response of Legionella pneumophila to antibiotics that inhibit cell-wall, protein and DNA synthesis was examined by electronmicroscopy, MIC estimations and viable counts.
(8) The MICs of the remaining anaerobes were 50 mug or less per ml.
(9) A kinetic turbidimetric Limulus amebocyte lysate (LAL) assay was used to study the effects of gentamicin, amoxycillin and ciprofloxacin (16 x MIC) upon release of lipopolysaccharide at different stages of a growing Escherichia coli 055:B5:H culture in vitro.
(10) Benzylpenicillin had an MBC value for the tolerant strains which was 256 times higher than the MIC; with the non-tolerant strain there was no difference.
(11) After 6 to 7 weeks exposure to sub-lethal concentrations of minocycline there was no appreciable increase in the MICs of most organisms with the exception of Actinobacillus actinomycetemcomitans NCTC 10981 and Campylobacter concisus NCTC 11485.
(12) Mutants resistant to R 61837 (up to 85 times the MIC) were shown to bear some cross-resistance (up to 23 times the MIC) to the new compound, indicating that pirodavir also binds into the hydrophobic pocket beneath the canyon floor of rhinoviruses.
(13) The antibiotic concentration in the agar at the zone edges was almost the same as the MIC of doxycycline against the test-cultures determined with the method of serial dilutions in agar.
(14) Urine concentrations remained in excess of the MIC for 90% of the relevant urinary tract pathogens for the full 12-h dosing interval at each dose.
(15) Also, the MIC of each antibiotic against different strains generally varied over a wide range.
(16) The mean MIC 50 for all 22 recorded species was in the susceptible range.
(17) MIC is clearly a well tolerated regime and among the most active combinations in non-small cell lung cancer.
(18) Paradoxical response to bactericidal activity of beta-lactams was abolished by incubation of the inoculum with 2 x MIC before exposure to higher antibiotic concentrations.
(19) The significance of MIC and MBC is discussed in connection with blood and tissue levels attainable during therapy and with the pharmacokinetic properties of a drug.
(20) There is poor correlation between the MICs and zone sizes obtained for erythromycin against Haemophilus influenzae.
Mico
Definition:
(n.) A small South American monkey (Mico melanurus), allied to the marmoset. The name was originally applied to an albino variety.
Example Sentences:
(1) "We need everything, we are underwater," mayor Mico Micic exclaimed.
(2) The antifungal azole drugs itraconazole (itra; R51,211), fluconazole (flu; UK-49,858), ketoconazole (keto) and micronazole (mico) have been investigated for their suppressive influence on the gene expression of the immunoregulatory cytokines IL2, IL4, IL9, GM-CSF, TNF-alpha, IFN-gamma, as well as both chains of the IL2 receptor in human PBMC and of the cytokines in the human keratinocyte cell line HaCat 17.5.
(3) Photograph: Mico Abrigo More than half said they had been “overlooked, ignored or denied service in a shop, restaurant or public office or transport”, while three-quarters said they had been stared at by strangers.