(1) Acquired drug resistance to INH, RMP, and EMB can be demonstrated in M. kansasii, and SMX in combination with other agents chosen on the basis of MIC determinations are effective in the treatment of disease caused by RMP-resistant M. kansasii.
(2) From 1983 to 1986 more than 2000 non-penicillinase producing Neisseria gonorrhoeae from Amsterdam, The Hague and Rotterdam were auxotyped and screened for susceptibility to 10 antibiotics by MIC determination.
(3) MICs of cefazolin and cefoxitin were also measured for Escherichia coli.
(4) MICs of chlortetracycline were 8 to 16 times higher than MICs of the other tetracyclines.
(5) MICs for the tested molecules correlate strongly with their binding parameters.
(6) After that during 14 days the concentration of gentamicin in the implantation zone maintained at the level higher than its MIC for the main pathogens of wound infections.
(7) The response of Legionella pneumophila to antibiotics that inhibit cell-wall, protein and DNA synthesis was examined by electronmicroscopy, MIC estimations and viable counts.
(8) The MICs of the remaining anaerobes were 50 mug or less per ml.
(9) A kinetic turbidimetric Limulus amebocyte lysate (LAL) assay was used to study the effects of gentamicin, amoxycillin and ciprofloxacin (16 x MIC) upon release of lipopolysaccharide at different stages of a growing Escherichia coli 055:B5:H culture in vitro.
(10) Benzylpenicillin had an MBC value for the tolerant strains which was 256 times higher than the MIC; with the non-tolerant strain there was no difference.
(11) After 6 to 7 weeks exposure to sub-lethal concentrations of minocycline there was no appreciable increase in the MICs of most organisms with the exception of Actinobacillus actinomycetemcomitans NCTC 10981 and Campylobacter concisus NCTC 11485.
(12) Mutants resistant to R 61837 (up to 85 times the MIC) were shown to bear some cross-resistance (up to 23 times the MIC) to the new compound, indicating that pirodavir also binds into the hydrophobic pocket beneath the canyon floor of rhinoviruses.
(13) The antibiotic concentration in the agar at the zone edges was almost the same as the MIC of doxycycline against the test-cultures determined with the method of serial dilutions in agar.
(14) Urine concentrations remained in excess of the MIC for 90% of the relevant urinary tract pathogens for the full 12-h dosing interval at each dose.
(15) Also, the MIC of each antibiotic against different strains generally varied over a wide range.
(16) The mean MIC 50 for all 22 recorded species was in the susceptible range.
(17) MIC is clearly a well tolerated regime and among the most active combinations in non-small cell lung cancer.
(18) Paradoxical response to bactericidal activity of beta-lactams was abolished by incubation of the inoculum with 2 x MIC before exposure to higher antibiotic concentrations.
(19) The significance of MIC and MBC is discussed in connection with blood and tissue levels attainable during therapy and with the pharmacokinetic properties of a drug.
(20) There is poor correlation between the MICs and zone sizes obtained for erythromycin against Haemophilus influenzae.
Mir
Definition:
(n.) A Russian village community.
(n.) Same as Emir.
Example Sentences:
(1) Most anti-nicotinic acetylcholine receptor (AChR) antibodies in myasthenia gravis are directed against an immunodominant epitope or epitopes [main immunogenic region (MIR)] on the AChR alpha-subunit.
(2) The data challenge the concept that a MIR of the AChR is the principal stimulus for antibody production in MG and emphasize a potential pitfall in assuming seronegativity in MG on the basis of a single assay system.
(3) The likelihood of performing a surgical procedure in space will increase as the Soviet Mir space station is expanded and the Space Station Freedom becomes operational.
(4) Mir M7 is a spontaneous morphologically conditional mutant of Klebsiella pneumoniae which grows as round cells (cocci) at pH 7 and as normal rods at pH 5.8.
(5) The beta-subunits of insulin receptor in CHO, CIR-0, Monr-31, and MIR-2 were similarly phosphorylated.
(6) Amino acid composition was qualitatively similar in both strains, but Mir M7 cocci contained a higher amount of alanine and glucosamine.
(7) Eldar Mustafayev, a former Turkish Airlines representative who returned to farming when his employer left Crimea after the referendum, said the canal bringing drinking and irrigation water from Ukraine's Dnieper river into Crimea was dry near their village of Novy Mir.
(8) The mAb inhibition was not explainable by epitope competition because (1) the mAb was reactive with both Torpedo and human AChR, but antibodies in 85 of the MG sera did not bind to Torpedo AChR, and (2) the mAb blocked binding of rat anti-peptide antibodies to an alpha subunit region of the human AChR unrelated antigenically to the designated MIR region.
(9) This suggest that the majority of the human MG antibodies are also directed against the MIR.
(10) The three-dimensional and clavulanate double-disk potentiation tests were compared as procedures for the detection of extended-spectrum beta-lactamase production in 32 strains of Escherichia coli and Klebsiella pneumoniae, 31 of which produced TEM-1, TEM-2, TEM-3, TEM-4, TEM-5, TEM-7, TEM-8, TEM-9, TEM-10, TEM-12, TEM-101, SHV-1, SHV-2, SHV-3, SHV-4, SHV-5, CAZ-2, MIR-1, or an unidentified extended-spectrum beta-lactamase with a pI of 5.95, with some strains producing multiple beta-lactamases.
(11) Mir Ali is a hotbed of al-Qaida and Taliban militancy that has borne the brunt of a sharp escalation in US attacks this year.
(12) Two-dimensional NMR experiments [correlated spectroscopy (COSY) and two-dimensional transferred nuclear Overhauser enhancement spectroscopy (TR-NOESY)] have been applied to study the interactions of a monoclonal antibody (mAb) directed to the main immunogenic region (MIR) of the acetylcholine receptor (AChR), and four synthetic decapeptides from the MIR.
(13) Nick Kanas, a psychiatrist at the University of California, San Francisco, who has studied astronauts on the international space station and the Russian Mir station, said the crew face a tough time.
(14) The computer program MIR previously described (R. Bianchi, G.M.
(15) Fab fragments of an anti-MIR monoclonal antibody (mAb) or a mAb to the beta-subunit (neither of which causes antigenic modulation) were allowed to shield their corresponding regions on the AChR on the mouse muscle cell line BC3H1.
(16) Indices of JE transmission activity (vector abundance, pig seroconversions, and MIRs) increased proportionately with rainfall.
(17) We report the isolation and characterization of a strain of Bacillus, designed MIR 15, which appears to produce and excrete antimicrobials active against Gram-negative bacteria, but not against fungi.
(18) Chick dorsal root ganglion neurons thought to lack nicotinic acetylcholine receptors were not labeled by the anti-MIR mAb.
(19) The patient underwent a CT scan and MIR which showed a diffuse involvement of the ilium and sacrum along with the presence of two cysts (anterior and posterior).
(20) This is interpreted as the contribution to antigenic modulation of the anti-MIR antibody fraction in the human sera.