(n.) A small South American monkey (Mico melanurus), allied to the marmoset. The name was originally applied to an albino variety.
Example Sentences:
(1) "We need everything, we are underwater," mayor Mico Micic exclaimed.
(2) The antifungal azole drugs itraconazole (itra; R51,211), fluconazole (flu; UK-49,858), ketoconazole (keto) and micronazole (mico) have been investigated for their suppressive influence on the gene expression of the immunoregulatory cytokines IL2, IL4, IL9, GM-CSF, TNF-alpha, IFN-gamma, as well as both chains of the IL2 receptor in human PBMC and of the cytokines in the human keratinocyte cell line HaCat 17.5.
(3) Photograph: Mico Abrigo More than half said they had been “overlooked, ignored or denied service in a shop, restaurant or public office or transport”, while three-quarters said they had been stared at by strangers.
Moco
Definition:
(n.) A South American rodent (Cavia rupestris), allied to the Guinea pig, but larger; -- called also rock cavy.
Example Sentences:
(1) CP bonded firmly MoCo and did not release it efficiently unless aponitrate reductase was present in the incubation mixture.
(2) A Chlamydomonas reinhardtii molybdenum cofactor (MoCo)-carrier protein (CP), capable of reconstituting nitrate reductase activity with apoprotein from the Neurospora crassa mutant nit-1, was subjected to experiments of diffusion through a dialysis membrane and gel filtration.
(3) It is difficult to explain these results by a simple regulatory model; therefore, we reexamined the MoCo levels in chl2 plants using a sensitive, specific assay for MoCo: complementation of Neurospora MoCo mutant extracts.
(4) Thus MoCo is not involved in NR dimerization in higher plants, contrary to current assumptions.
(5) The amount of total MoCo (free, carrier-bound and heat releasable forms) was dependent on the growth phase of cell cultures.
(6) The Nucleus multichannel implantable hearing prosthesis (Nucleus Ltd., Sydney, Australia) has been modified by computer programming (MOCO, Inc., Scituate, Mass.)
(7) Constitutive levels of total MoCo in ammonium-grown cells markedly increased when cells were transferred to media lacking ammonium (nitrate, urea or nitrogen-free media).
(8) Stability of MoCo bound to CP against air and heat was very similar to that of free-MoCo released from milk xanthine oxidase.
(9) Ltd., Lane Cove, Sydney, Australia) has been modified by computer programming (MOCO, Inc., Scituate, Mass.
(10) Biochemical data suggest that the haem and FAD domains are functional, and that the molybdenum cofactor (MoCo) domain is inactive owing to the absence of MoCo in yeast.
(11) In addition, chl2 plants are not thought to be defective in MoCo, as they have near wild-type levels of xanthine dehydrogenase activity, which has been used as a measure of MoCo in other organisms.
(12) Hundreds of chlorate-resistant mutants have been identified in plants, and almost all have been found to be defective in nitrate reduction due to mutations in either nitrate reductase (NR) structural genes or genes required for the synthesis of the NR cofactor molybdenum-pterin (MoCo).
(13) Results suggest that MoCo is continuously synthesized in C. reinhardtii and that its levels are regulated by ammonium in a way independent of nitrate reductase synthesis.
(14) Our data strongly suggest that MoCo is directly transferred from CP to aponitrate reductase to form an active enzyme.
(15) Levels of both total MoCo and free plus carrier-bound MoCo seemed to be unrelated to either nitrate reductase synthesis or functioning of nit-1 and nit-2 genes responsible for nitrate reductase structure and regulation, respectively.
(16) The MoCo oxidation product from C. reinhardtii has the same chromatographic and spectral properties as that of milk xanthine oxidase and chicken liver sulfite oxidase.
(17) In soluble form, MoCo was found to be present in several forms: (i) as a low Mr free species; (ii) bound to a MoCo-carrier protein of about 50 kDa that could release MoCo to directly reconstitute in vitro nitrate reductase activity in the nit-1 mutant of Neurospora crassa, but not to Thiol-Sepharose which, in contrast, bonded free MoCo; and (iii) bound to other proteins, putatively constitutive molybdoenzymes, which only released MoCo after a denaturing treatment.
(18) A simple and reliable procedure of oxidation of molybdenum cofactor (MoCo) from molybdoenzymes by autoclaving samples at 120 degrees C for 20 min yielded a single predominant fluorescent species that could be quantitatively determined by reverse phase high performance liquid chromatography.
(19) Molybdenum cofactor (MoCo) of molybdoenzymes is constitutively produced in cells of the green alga Chlamydomonas reinhardtii grown in ammonium media, under which conditions certain molybdoenzymes are not synthesized.