(1) Local infusion of high concentrations of GABA or GABA mimetics into the striatum, septum or substantia nigra failed to modify 5-HTP accumulation in these areas.
(2) A possible cellular basis for dopaminergic sensitization by long-term dopamine mimetics was examined in rat brain striatum.
(3) Selective beta-mimetic drugs are the most frequently used agents for arresting preterm labour.
(4) The results are interpreted on the basis of the chemical structure and conformations of the ionophores in membrane mimetic media.
(5) We studied a role of TXA2 in the development of PAF-induced nonspecific airway hyperresponsiveness in guinea pigs using a TXA2 synthetase inhibitor (OKY-O46.HCl) and a stable TXA2 mimetic agent (STA2).
(6) In order to confirm these findings, we have studied the effect of GABA mimetics on extracellular DOPAC in the locus coeruleus (a reliable index of noradrenergic neuronal activity) of the rat through the use of in vivo voltammetry with carbon fibre electrodes.
(7) Vanadate possesses insulin-mimetic effects, and has been reported to correct the metabolic imbalances in streptozotocin-induced diabetes.
(8) With regard to the ST-depression, a possible physiological adaptation to the beta-mimetic drug is described.
(9) The novel antibacterial peptide mimetic alaphosphin (l-alanyl-l-1-aminoethylphosphonic acid) selectively inhibited peptidoglycan biosynthesis in both gram-negative and gram-positive bacteria.
(10) Two series of 1,2,4-triazolo[4,3-a]pyrazine derivatives with human renin inhibitory activity have been synthesized which incorporate the transition-state mimetics (3S,4S)- and (3R,4S)-5-cyclohexyl-3,4-diaminopentanoic acid ((S)- and (R)-CDAPA), and (4S)-4-amino-5-cyclohexyl-2,2-difluoro-3-oxopentanoic acid (ACDFOPA).
(11) A novel selective PDE V inhibitor, SK&F 96231, reversed the bronchoconstriction induced in anaesthetised guinea pigs by histamine, a thromboxane-mimetic or by ovalbumin challenge.
(12) The effect of lowering total plasma and low density lipoprotein (LDL) cholesterol in heterozygous familial hypercholesterolaemia type IIa (FH) on platelet function, thromboxane (TX) formation and platelet sensitivity against iloprost, a stable prostacyclin mimetic, was studied in platelet-rich plasma ex vivo.
(13) Blockade of these beta-mimetic effects resulted in a fall in uterine blood flow as the perfusion pressure was reduced.
(14) The majority of the remaining damage could be blocked, in a dose-dependent manner, by superoxide dismutase (SOD) or a SOD-mimetic copper complex, identifying a fraction of damage to intracellular DNA dependent upon extracellular O2-.
(15) Dopamine (DA) and DA-mimetics (apomorphine, midantan, piribedil) have a dual effect on Na, K-ATPase of the rat brain striate synaptosomes: activating at micromolar concentrations and inhibitory at higher concentrations (less than or equal to 30 microM).
(16) The lymphatics were mounted in tissue baths, and isometric contractions were induced by increasing concentrations of the thromboxane A2 (TXA2) mimetic U-46619.
(17) BAY u3405 was a potent, and competitive, antagonist of the TXA2-mimetic U46619-induced contractions of human, guinea-pig, rat and ferret airway smooth muscle with pA2 values between 8.0 and 8.9 and with no inherent contractile activity (10(-9)-10(-4) M).
(18) The overall pattern of decreased glucose use seen with progabide was different from that noted with previously studied GABA-mimetic drugs, such as muscimol, except for those changes observed in the extrapyramidal and sensory-motor areas for which similar dose-response relationships occurred.
(19) Peptides of portions of loop 2 (the "toxic" loop) of snake venom curare-mimetic neurotoxins (alpha-bungarotoxin and king cobra toxin b) and of a structurally similar region of the rabies virus glycoprotein were synthesized.
(20) Relaxation to bradykinin of rings contracted with the thromboxane A2 mimetic U-46619 was not affected by L-NMMA and was only minimally inhibited by methylene blue.
Mnemonic
Definition:
(a.) Alt. of Mnemonical
Example Sentences:
(1) The selected students had normal intellectual capacity but often showed inadequate progress in school, attentive-mnemonic deficiencies, and psychopathological elements of a depressive nature.
(2) Although those receiving active pretraining plus mnemonics did not differ from one another at Time 3, they recalled more than those with no active pretraining.
(3) This more recent system has developed embedded wlithin the posteriorly located analytic and mnemonic cortical tissues and provides for communications between individuals within the species at symbolic, verbal levels.
(4) No consistent hemispheric specialization nor difference in direction of interhemispheric communication was observed despite the use of different types of material and the different mnemonic tasks.
(5) It is suggested that natural analogs of pyrimidine, whose precursor is orotic acid, are universal endogenous regulators of mnemonic and antianxiety functions.
(6) The young group showed significantly higher recall and recognition (both immediate and delayed) for the digit-symbol pairs and were more likely to report the use of mnemonic techniques in learning the pairs.
(7) Thus, theta-rhythm may play a modulating role in the induction of LTP, suggesting a possible mnemonic function for the rhythm during the behaviors in which it occurs.
(8) A combination of drugs dilating the heart vessels with drugs improving metabolism and the brain blood flow resulted in an improvement of mnemonic function.
(9) Women must be taught the serious adverse effects to watch for: a mnemonic "ACHES" is suggested.
(10) The effect of intravenous atropine (1 mg) or saline on mnemonic function was tested in patients with various forms of dementia and age-matched controls.
(11) These results indicate that animals showing a definitive sign of tolerance to OP administration (subsensitivity to a cholinergic agonist) were also functionally impaired on both the mnemonic and motoric demands of a working memory task.
(12) In essence, it is argued that the human amygdala is responsible for activating or reactivating those mnemonic events which are of an emotional significance for the subjects' life history and that this (re-)activation is performed by charging sensory information with appropriate emotional cues.
(13) Sixty-two normal elderly subjects averaging 71 years old were taught a common mnemonic device for recall of lists using a Computer-Aided Instruction (CAI) package.
(14) In summary, these results indicate that primate prefrontal cortex participates in visual information processing and may code several aspects of visual stimuli including behavioral significance and mnemonic representations.
(15) These results suggest that frequency-specific RF plasticity in the MGv may be a substrate of short-term mnemonic processes that could participate in long-term storage of information and modification of the representation of the CS at the auditory cortex.
(16) This finding identifies a neurochemical change associated with classical conditioning which is similar to the increase in transmitter release seen in hippocampal long-term potentiation (LTP), and which is consistent with the hypothesis that an LTP-like mechanism is involved in mnemonic processes.
(17) Activation by vaginocervical stimulation of the "mnemonic" neurogenic system that controls the autonomous nocturnal prolactin surges did not interfere with the reflexive pup-induced release of prolactin in maternally behaving virgins.
(18) The deteriorating effect of amphetamine on mnemonic processes and its facilitatory effect on behaviors directed to get more than the usual amount of pleasant tactile stimulation might underlie the behavioral changes described in this study.
(19) The study of this effect in the case of poly(dA).oligo(dT) replication led us to propose a mnemonic model for Pol I, in which the 3' to 5' excision activity warms up when the enzyme is actively polymerizing, and cools down when it dissociates from the template.
(20) Although mnemonic interpretations of hippocampal function in people have been readily accepted for many years, similar interpretations of hippocampal function in animals have received a number of challenges.