(n.) One who imitates or mimics, especially one who does so for sport; a copyist; a buffoon.
(v. t.) To imitate or ape for sport; to ridicule by imitation.
(v. t.) To assume a resemblance to (some other organism of a totally different nature, or some surrounding object), as a means of protection or advantage.
Example Sentences:
(1) The mechanism by which gp55 causes increased erythroblastosis and ultimately leukaemia is unknown, but a reasonable suggestion is that gp55 can mimic the action of erythropoietin by binding to its receptor (Epo-R), thereby triggering prolonged proliferation of erythroid cells.
(2) The present study explored the possibility that SOD-mimics such as desferrioxamine-Mn(III) chelate [DF-Mn] or cyclic nitroxide stable free radicals could protect from O2-.-independent damage.
(3) In physiological studies CDS mimics clonidine's action as an inhibitor of the electrically induced twitch response and as a partial agonist of the epinephrine-induced platelet aggregation.
(4) It may be assumed that this trait in the evaluation of mimics is due to a constitutional and morbid process.
(5) Mimics are stars and the country’s finest impersonators have their own television shows.
(6) The diagnosis of porphyria was overlooked in some as the symptoms may mimic those of other acute illnesses, so that incomplete or incorrect death certificates have been issued.
(7) The neurotransmitter alterations which accompany aluminum neurofibrillary degeneration were examined in order to assess how closely they mimic those of Alzheimer's disease.
(8) of cAMP-dependent protein kinase (cAMP-PK) mimics this effect.
(9) Loads up to 2.5 kN were applied, without simulated muscle forces, to mimic the line-of-action of the resultant joint-force in a single-legged stance.
(10) Veryan has developed a stent – a metal mesh tube inserted in an artery – that mimics the natural swirl of the blood flow, which researchers have found improves outcomes for patients with circulation problems.
(11) To mimic physiological conditions, synaptosomes, which are pinched off presynaptic nerve termini, were used.
(12) Again, the ability of lead to mimic or mobilize calcium and activate protein kinases may alter the behavior of endothelial cells in immature brain and disrupt the barrier.
(13) ADP and ATP gamma S were able to mimic the ATP response, whereas AMP and adenosine were unable to elicit a Cl- current.
(14) This peptide appeared to be a strong agonist of FSH action, as measured by the ability to stimulate cAMP production, at concentrations as low as 10(-7) M. The observation that a synthetic peptide, in which (parts of) three earlier described receptor interaction sites are combined according to the three-dimensional model, can mimic the action of FSH, at 10(-7) M, shows that this model is useful to predict a conformational receptor-binding site in FSH and that combination of only a few amino acid residues from the alpha and beta chains of FSH in a small synthetic peptide is sufficient to transduce a signal upon binding to the receptor.
(15) These uncommon ulcers, which mimic carcinoma radiographically and were previously thought to be uniformly fatal, may occasionally heal spontaneously.
(16) Aminophylline and caffeine can mimic this effect; however, papaverine and 1-methyl-3-isobutylxanthine, at concentrations inhibitory to phosphodiesterase, are without effect on glucocorticoid receptor binding to DNA.
(17) There is thus need for models that could mimic such situations.
(18) The present findings demonstrate that exogenously administered cholinomimetics only partly mimic the action of endogenous acetylcholine in the hippocampus.
(19) Histopathologically, the lesions display caseating and noncaseating dermal granulomas that mimic those seen in tuberculosis, tuberculoid leprosy, sarcoidosis, and other diseases.
(20) Cardiac myxomas typically present as a triad of obstructive, embolic, and constitutional symptoms and thus mimic many more common systemic illnesses.
Mimicry
Definition:
(n.) The act or practice of one who mimics; ludicrous imitation for sport or ridicule.
(n.) Protective resemblance; the resemblance which certain animals and plants exhibit to other animals and plants or to the natural objects among which they live, -- a characteristic which serves as their chief means of protection against enemies; imitation; mimesis; mimetism.
Example Sentences:
(1) Antigenic mimicry by T. cruzi antigens sharing epitopes with host macromolecules has been implicated in the pathogenesis which is thought to have a significant autoimmune component.
(2) To investigate the possible involvement of epitopes shared by microbial antigens and host self-components in initiation of autoimmunity (molecular mimicry), a sequence data bank was screened for proteins containing an amino acid motif identical or related to ERKRR.
(3) The homology thus revealed not only lends strong support to mechanisms of autoimmunity that invoke the theory of molecular mimicry of viral proteins, but also suggests a rationale for the skeletal muscle target of polymyositis.
(4) They include antigenic variation, antigenic polymorphism, antigenic mimicry and direct interference with the generation of the host immune response.
(5) The basis of the stimulation of this group of autoantibodies is at least in part due to antigenic mimicry between the envelope protein VP3 of LDV and determinants of intermediate filaments, since a panel of monoclonal antibodies cross-reacts with both.
(6) The role of molecular mimicry in the spondyloarthropathies was investigated with respect to the epitopes involved.
(7) The possibility of molecular mimicry (antibody cross-reactivity between LCM and RBC membrane epitopes) was considered but appeared unlikely since the RBC antibody eluates gave no signal in an LCM-specific ELISA (which showed an ever increasing serum titer of virus-specific antibody).
(8) To examine how mimicry was influenced by a person's power and the status of those around them, Carr asked 55 volunteers to watch videos of high-status people (such as a doctor or business leader) or low-status people (a worker in a fast food restaurant, say, or a rubbish collector) either being happy or angry.
(9) Although several means have been hypothesized to play a role in disease, a widely accepted mechanism for viral-induced autoimmunity is molecular mimicry.
(10) In an effort to understand the structural basis for antigen mimicry by internal image antibodies, we determined the variable (V) region sequences of two mouse mAbs that mimic the rabbit Ig a1 allotype.
(11) Phenotypic switching and molecular mimicry may also provide the organism with an arsenal of mechanisms to evade host defenses.
(12) The binding of antibodies in the sera of patients with Lyme arthritis to the NH2-terminal region of the flagellar protein, a region with sequence homology to the flagellar proteins of other bacterial species, suggests the possibility that antigenic mimicry contributes to the immunopathogenesis of Lyme disease.
(13) Antigenic mimicry has been demonstrated to be operative, since they are cross-reactive to viral proteins.
(14) Although the thickness of the soft tissue is dependent on exogenous factors, such as nutrition, mimicry, and so forth, the dimensions of the bony nose apparently also influence the skin depths to some extent.
(15) Molecular mimicry or epitope similarity between group A streptococcal M proteins and myosin may contribute to the presence of heart reactive antibodies in acute rheumatic fever.
(16) Our results show that the macromolecular assemblage approach bears immunological mimicry of the gp120 of HIV virus and may lead to useful vaccines against HIV infection.
(17) Variations in the antigenic behaviour of parasites and their immunological mimicry by uptake of substances from the host and their immunosuppressive action are discussed.
(18) Hence it is not likely to be involved in the pathogenesis of HAM through molecular mimicry.
(19) It has been suggested that molecular mimicry might be a reason for autoimmunity as a result of immunological cross reactivity.
(20) Other mechanisms including antigenic mimicry by capsular polysaccharides and antigenic masquerade by immunoglobulin fragments confer additional resistance to the extracellular life style of these organisms.