(n.) The act or practice of one who mimics; ludicrous imitation for sport or ridicule.
(n.) Protective resemblance; the resemblance which certain animals and plants exhibit to other animals and plants or to the natural objects among which they live, -- a characteristic which serves as their chief means of protection against enemies; imitation; mimesis; mimetism.
Example Sentences:
(1) Antigenic mimicry by T. cruzi antigens sharing epitopes with host macromolecules has been implicated in the pathogenesis which is thought to have a significant autoimmune component.
(2) To investigate the possible involvement of epitopes shared by microbial antigens and host self-components in initiation of autoimmunity (molecular mimicry), a sequence data bank was screened for proteins containing an amino acid motif identical or related to ERKRR.
(3) The homology thus revealed not only lends strong support to mechanisms of autoimmunity that invoke the theory of molecular mimicry of viral proteins, but also suggests a rationale for the skeletal muscle target of polymyositis.
(4) They include antigenic variation, antigenic polymorphism, antigenic mimicry and direct interference with the generation of the host immune response.
(5) The basis of the stimulation of this group of autoantibodies is at least in part due to antigenic mimicry between the envelope protein VP3 of LDV and determinants of intermediate filaments, since a panel of monoclonal antibodies cross-reacts with both.
(6) The role of molecular mimicry in the spondyloarthropathies was investigated with respect to the epitopes involved.
(7) The possibility of molecular mimicry (antibody cross-reactivity between LCM and RBC membrane epitopes) was considered but appeared unlikely since the RBC antibody eluates gave no signal in an LCM-specific ELISA (which showed an ever increasing serum titer of virus-specific antibody).
(8) To examine how mimicry was influenced by a person's power and the status of those around them, Carr asked 55 volunteers to watch videos of high-status people (such as a doctor or business leader) or low-status people (a worker in a fast food restaurant, say, or a rubbish collector) either being happy or angry.
(9) Although several means have been hypothesized to play a role in disease, a widely accepted mechanism for viral-induced autoimmunity is molecular mimicry.
(10) In an effort to understand the structural basis for antigen mimicry by internal image antibodies, we determined the variable (V) region sequences of two mouse mAbs that mimic the rabbit Ig a1 allotype.
(11) Phenotypic switching and molecular mimicry may also provide the organism with an arsenal of mechanisms to evade host defenses.
(12) The binding of antibodies in the sera of patients with Lyme arthritis to the NH2-terminal region of the flagellar protein, a region with sequence homology to the flagellar proteins of other bacterial species, suggests the possibility that antigenic mimicry contributes to the immunopathogenesis of Lyme disease.
(13) Antigenic mimicry has been demonstrated to be operative, since they are cross-reactive to viral proteins.
(14) Although the thickness of the soft tissue is dependent on exogenous factors, such as nutrition, mimicry, and so forth, the dimensions of the bony nose apparently also influence the skin depths to some extent.
(15) Molecular mimicry or epitope similarity between group A streptococcal M proteins and myosin may contribute to the presence of heart reactive antibodies in acute rheumatic fever.
(16) Our results show that the macromolecular assemblage approach bears immunological mimicry of the gp120 of HIV virus and may lead to useful vaccines against HIV infection.
(17) Variations in the antigenic behaviour of parasites and their immunological mimicry by uptake of substances from the host and their immunosuppressive action are discussed.
(18) Hence it is not likely to be involved in the pathogenesis of HAM through molecular mimicry.
(19) It has been suggested that molecular mimicry might be a reason for autoimmunity as a result of immunological cross reactivity.
(20) Other mechanisms including antigenic mimicry by capsular polysaccharides and antigenic masquerade by immunoglobulin fragments confer additional resistance to the extracellular life style of these organisms.
Simulate
Definition:
(a.) Feigned; pretended.
(v. t.) To assume the mere appearance of, without the reality; to assume the signs or indications of, falsely; to counterfeit; to feign.
Example Sentences:
(1) It is concluded that during exposure to simulated microgravity early signs of osteoporosis occur in the tibial spongiosa and that changes in the spongy matter of tubular bones and vertebrae are similar and systemic.
(2) We present a mathematical model that is suitable to reconcile this apparent contradiction in the interpretation of the epidemiological data: the observed parallel time series for the spread of AIDS in groups with different risk of infection can be realized by computer simulation, if one assumes that the outbreak of full-blown AIDS only occurs if HIV and a certain infectious coagent (cofactor) CO are present.
(3) A Monte Carlo simulation was performed to characterize the spatial and energy distribution of bremsstrahlung radiation from beta point sources important to radioimmunotherapy (RIT).
(4) Angus (A), Charolais (C), Hereford (H), Limousin (L), and Simmental (S) breeds were included in deterministic computer models simulating integrated cow-calf-feedlot production systems.
(5) The design of a simple dynamic knee simulator is described.
(6) Our results suggest that during simulated ischemia the rate-dependent component of the increase in Ri contributes to the rate-dependence of the conduction slowing.
(7) The purposes of this study were to locate games and simulations available for nursing education, to categorize these materials to make them more accessible for nurse educators, and to determine how nursing's use of instructional games might be enhanced.
(8) It is intended to aid in finding the appropriate PI (proportional-integral) controller settings by means of computer simulation instead of real experiments with the system.
(9) The authors conclude that there is no heart rate-dependent signal loss in healthy persons that simulates valvular dysfunction, thus suggesting that signal intensity change can be used as an indicator for this disease, independent of heart rate.
(10) Dysplasia epiphysealis hemimelica - an epiphyseal developmental disturbance of the skeleton - is combined with exostose-like, tumor-simulating cartilaginous hypertrophy of bone tissue, mainly located at the epiphyses of the lower extremities and at the tarsal bones.
(11) Femoral angiograms were made in 21 cadavers under simulated clinical conditions, with a pressurized radiopaque casting material.
(12) A rubber cuff was fixed on the metal cylinder and let an opening of 8 cm, simulating the cervix uteri.
(13) It is suggested that this human model of unloading could serve to simulate effects of microgravity on skeletal muscle mass and function because reductions in muscle mass and strength were of similar magnitude to those produced by bed rest.
(14) To test this, a physiologic-based kinetic model was developed to simulate drug concentrations in brain and blood in the presence and absence of CNS metabolism.
(15) Echo delay discrimination by the bat Eptesicus fuscus had been investigated in an experiment with simulated targets jittering in range (Simmons 1979).
(16) Using the rate coefficient values found by SCoPfit, we simulated a voltage-clamp experiment with both models running under their Na(+)-Na+ exchange mode, and we computed the transient currents generated following voltage steps in both depolarizing and hyperpolarizing directions from a basic potential of -40 mV.
(17) By using increased feed-forward gain in a sampled-data control model we simulated the pattern of macrosaccadic oscillation.
(18) Studies on antimicrobial effect kinetics in dynamic models in vitro simulating pharmacokinetic profiles observed in humans markedly promote the problem solution.
(19) The technique was applied to the classification of MUAP's extracted from simulated myoelectric signals.
(20) The latter animals were raised in an automated feeding device (Autosow) with an artificial diet simulating the nutritional composition of sow milk.