(1) Most anti-nicotinic acetylcholine receptor (AChR) antibodies in myasthenia gravis are directed against an immunodominant epitope or epitopes [main immunogenic region (MIR)] on the AChR alpha-subunit.
(2) The data challenge the concept that a MIR of the AChR is the principal stimulus for antibody production in MG and emphasize a potential pitfall in assuming seronegativity in MG on the basis of a single assay system.
(3) The likelihood of performing a surgical procedure in space will increase as the Soviet Mir space station is expanded and the Space Station Freedom becomes operational.
(4) Mir M7 is a spontaneous morphologically conditional mutant of Klebsiella pneumoniae which grows as round cells (cocci) at pH 7 and as normal rods at pH 5.8.
(5) The beta-subunits of insulin receptor in CHO, CIR-0, Monr-31, and MIR-2 were similarly phosphorylated.
(6) Amino acid composition was qualitatively similar in both strains, but Mir M7 cocci contained a higher amount of alanine and glucosamine.
(7) Eldar Mustafayev, a former Turkish Airlines representative who returned to farming when his employer left Crimea after the referendum, said the canal bringing drinking and irrigation water from Ukraine's Dnieper river into Crimea was dry near their village of Novy Mir.
(8) The mAb inhibition was not explainable by epitope competition because (1) the mAb was reactive with both Torpedo and human AChR, but antibodies in 85 of the MG sera did not bind to Torpedo AChR, and (2) the mAb blocked binding of rat anti-peptide antibodies to an alpha subunit region of the human AChR unrelated antigenically to the designated MIR region.
(9) This suggest that the majority of the human MG antibodies are also directed against the MIR.
(10) The three-dimensional and clavulanate double-disk potentiation tests were compared as procedures for the detection of extended-spectrum beta-lactamase production in 32 strains of Escherichia coli and Klebsiella pneumoniae, 31 of which produced TEM-1, TEM-2, TEM-3, TEM-4, TEM-5, TEM-7, TEM-8, TEM-9, TEM-10, TEM-12, TEM-101, SHV-1, SHV-2, SHV-3, SHV-4, SHV-5, CAZ-2, MIR-1, or an unidentified extended-spectrum beta-lactamase with a pI of 5.95, with some strains producing multiple beta-lactamases.
(11) Mir Ali is a hotbed of al-Qaida and Taliban militancy that has borne the brunt of a sharp escalation in US attacks this year.
(12) Two-dimensional NMR experiments [correlated spectroscopy (COSY) and two-dimensional transferred nuclear Overhauser enhancement spectroscopy (TR-NOESY)] have been applied to study the interactions of a monoclonal antibody (mAb) directed to the main immunogenic region (MIR) of the acetylcholine receptor (AChR), and four synthetic decapeptides from the MIR.
(13) Nick Kanas, a psychiatrist at the University of California, San Francisco, who has studied astronauts on the international space station and the Russian Mir station, said the crew face a tough time.
(14) The computer program MIR previously described (R. Bianchi, G.M.
(15) Fab fragments of an anti-MIR monoclonal antibody (mAb) or a mAb to the beta-subunit (neither of which causes antigenic modulation) were allowed to shield their corresponding regions on the AChR on the mouse muscle cell line BC3H1.
(16) Indices of JE transmission activity (vector abundance, pig seroconversions, and MIRs) increased proportionately with rainfall.
(17) We report the isolation and characterization of a strain of Bacillus, designed MIR 15, which appears to produce and excrete antimicrobials active against Gram-negative bacteria, but not against fungi.
(18) Chick dorsal root ganglion neurons thought to lack nicotinic acetylcholine receptors were not labeled by the anti-MIR mAb.
(19) The patient underwent a CT scan and MIR which showed a diffuse involvement of the ilium and sacrum along with the presence of two cysts (anterior and posterior).
(20) This is interpreted as the contribution to antigenic modulation of the anti-MIR antibody fraction in the human sera.
Pet
Definition:
(n.) A cade lamb; a lamb brought up by hand.
(n.) Any person or animal especially cherished and indulged; a fondling; a darling; often, a favorite child.
(n.) A slight fit of peevishness or fretfulness.
(a.) Petted; indulged; admired; cherished; as, a pet child; a pet lamb; a pet theory.
(v. t.) To treat as a pet; to fondle; to indulge; as, she was petted and spoiled.
(v. i.) To be a pet.
Example Sentences:
(1) In cases with unilateral hypoperfusion, the percentage of the activity in the lesion to that in the contralateral normal cortex on the early SPECT was correlated well with that on CBF measured by PET (r = 0.870, p less than 0.001).
(2) However, localizing a functional region with PET has been severely limited by the poor resolving properties of PET devices.
(3) The PET studies suggest dysfunction of the prefrontal cortex as a result of damage to the lentiform nuclei.
(4) If the PET measurement is commenced prior to arteriovenous equilibrium, significant errors occur in calculated CBV.
(5) Single photon emission computed tomography (SPECT) and positron emission tomography (PET) are now being used to improve the information available from radioisotopic imaging of patients with cancer.
(6) The muscarinic receptor agonist carbachol had no significant effects on [3H]PEt and [3H]IP formation in nontransfected HEK cells.
(7) Appropriate corrections for atrophy should be employed if current PET scanners are to accurately measure actual brain tissue metabolism in various pathologic states.
(8) Using a 1-stage random-digit dial telephone survey, we estimated the number of pet dogs and cats and cancer case ascertainment in the principal catchment area of an animal tumor registry in Indiana, the Purdue Comparative Oncology Program (PCOP).
(9) Such information could be most useful for in vivo receptor visualization studies using positron emission tomography (PET) scanning.
(10) Half the adolescents completed the child maltreatment instrument first, while the rest completed the pet maltreatment instrument.
(11) In this study, PET images were obtained using [18F]-labeled fluorodeoxyglucose, a marker for glucose metabolism.
(12) The global black market in animal and plants, sold as food, traditional medicines and exotic pets, is worth billions and sees an estimated 350 million specimens traded every year.
(13) The distribution of 1-11C-acetoacetic acid after injection into adult Wistar rats and cats was investigated by PET.
(14) If we start letting movie stars – even though they’ve been the sexiest man alive twice – to come into our nation (with pets), then why don’t we just break the laws for everybody?” Joyce said at the time.
(15) We have developed a method that allows two sets of regional cerebral metabolic rates of glucose (rCMRglc) to be obtained in a single extended procedure using positron emission tomography (PET) and [18F]fluorodeoxyglucose (FDG).
(16) Metabolic PET studies also give insight into pathophysiologic mechanisms of epilepsy.
(17) In view of the number of PET studies involving low count rate acquisitions, there has been increasing interest recently in the development of positron cameras capable of fully three-dimensional acquisition and reconstruction.
(18) We performed dynamic positron emission tomographic (PET) studies of glucose utilization, using (18F) 2-fluoro-2-deoxy-D-glucose (FDG), in patients with probable Alzheimer's disease (AD) and healthy age-matched controls, to evaluate blood-brain-barrier glucose transport and glucose utilization rates in the disease.
(19) We used a 11C-glucose method for positron emission tomography (PET) while estimating cerebral glucose metabolism during human sleep with polysomnography (PSG).
(20) His mother is Denise Welch, late of Corrie and Loose Women, and his father his Tim Healy, who was briefly famous 30 years ago for his role in Auf Wiedersehen, Pet.