(1) Maybe there was a wish to go for these stronger story formulations, more extreme situations to try to get the energy up to comfortably blow the lid off.” Miller pointed out to Franzen that he has developed something of a reputation as a misanthrope.
(2) This misanthropic masterpiece says it all for them.
(3) Williams's Cat On a Hot Tin Roof, with its all-black cast, won best revival, beating strong competition that included The Misanthrope and A View From the Bridge.
(4) I am not a misanthrope (or not entirely) but I like my experience of nature to be unmediated by the presence of other members of my species, and so I stay away from the venues where the tourists gather en masse.
(5) Jonathan Franzen on his misanthropic reputation: 'We live in a world of cant' Read more While the novelist blamed himself for the incident, he admitted he also blamed Winfrey.
(6) The West End debut of Keira Knightley will irresistibly get all the headlines and shift a lot of the tickets, though the rest of the cast of The Misanthrope – including Damian Lewis, Dominic Rowan and Tara Fitzgerald – are not exactly duffers.
(7) "I was busy being misanthropic and miserable, as most 13-year-olds are.
(8) Scalia was, as usual, the episode's garish, garrulous villain, the kind of lusty misanthrope the word "harrumph" erupts from.
(9) People think I'm crabby having seen the new movie, (1) but I'm not this misanthrope who sits in a dark room, smoking, writing comments under YouTube clips.
(10) They leave the zoo, and close the door and we are left ... " He trails off, the professional churl and pretend misanthrope.
(11) Let's make Alceste fall in love with Jennifer, an American film star, whose shameless manipulation of her powerful friends, strategic sexual provocation and delight in malicious chatter makes her, like The Misanthrope's Célimène, represent everything he most hates.
(12) Her quiet lifestyle, gamine looks and infrequent personal appearances have fuelled her reputation as a misanthropic genius.
(13) To critics who consider Rand's philosophy that " of the psychopath, a misanthropic fantasy of cruelty, revenge and greed ", her posthumous success is alarming.
(14) Known for having starred as child actors in the communist-era film The Two Who Stole the Moon, theirs was a symbiotic political dynamic, with the more softly spoken and personable Lech softening the image of the vitriolic and misanthropic Jarosław.
(15) Amazing – but at the same time worrying: how can his play The Misanthrope have any purchase on a world of such egalitarian transparency?
(16) I have even heard the cynically misanthropic opinion that, without the Bible as a moral compass, people would have no restraint against murder, theft and mayhem.
(17) This isn't easy, for Travers is a misanthrope, highly strung and fiercely protective of her books.
(18) I've found that the songs that come out of nastier, more misanthropic places are better.
(19) "I have heard the cynically misanthropic opinion that without the Bible as a moral compass people would show no restraint against murder, theft and mayhem.
(20) When I put it to him that, like Brooker, there's a liberal heart beating behind the misanthropic exterior (he's fiercely pro-choice and pro-drugs), he disagrees.
Reprobate
Definition:
(a.) Not enduring proof or trial; not of standard purity or fineness; disallowed; rejected.
(a.) Abandoned to punishment; hence, morally abandoned and lost; given up to vice; depraved.
(a.) Of or pertaining to one who is given up to wickedness; as, reprobate conduct.
(n.) One morally abandoned and lost.
(v. t.) To disapprove with detestation or marks of extreme dislike; to condemn as unworthy; to disallow; to reject.
(v. t.) To abandon to punishment without hope of pardon.
Example Sentences:
(1) The biotin and its attached streptavidin and radiolabel can be removed under mild conditions and the blot reprobed with a different antibody using an identical protocol.
(2) Replacing radioactively labeled probes by nonradioactive ones and detection by chemiluminescence instead of colorimetry allows a nonhazardous handling and offers the possibility of easily reprobing filters in Southwestern analysis.
(3) Repeated strippings and heterologous reprobings resulted in loss of target DNA from UV-immobilized nylon membranes as compared to baked nylon membranes.
(4) Thirty-three of sixty-one flies reprobed with an Endotrypanum probe were positive.
(5) The recurrent dacryocystocele was reprobed and the abnormality was resolved.
(6) DNA from the cDNA-positive cosmid clones was transferred to nylon filters and reprobed with cDNAs to identify restriction fragments that were expressed in these tissues.
(7) How did the Republican party allow that reprobate to hijack it?
(8) Northern blots reprobed with H1t-specific oligonucleotide showed that H1t mRNA remained prominent when TH2B mRNA started to decline after 8-12 days of coculture.
(9) A first technique allows to detect zinc- and DNA-binding proteins immobilized on the membrane; a second (a modification of Southern-Western blotting) makes it possible to detect DNA-binding proteins followed by immunological reprobing.
(10) He whips out his smartphone and records the scene, documenting the offence, and confronts the suspected reprobate with a voice which can boom across a street: “Hey!” California drought shaming takes on a class-conscious edge Read more Corcoran is a drought-shamer.
(11) New probes, based on sequence that lies beyond other restriction sites, are then synthesized, and the membranes are reprobed to reveal new sequence.
(12) Analysis with direct beta counting was also shown not to interfere with the successful reprobing of stripped dot blots with either unique sequence or total genomic probes.
(13) In the longer term the Conservatives only get away with supporting universal values like the rule of law and human rights while also condemning non-white foreigners, immigrants and benefit scroungers, because they are always silently whistling that none of the values we supposedly uphold apply to these reprobates.
(14) Many specimens among 37 other serum samples showed greater or lesser degrees of homology to different probes, as demonstrated by reprobing of samples fixed to nylon membranes.
(15) The hybridized nylon membranes could be stripped of probe and reprobed at least 6 times without loss of signal strength.
(16) These conceptions and their cultural influences incidentally inform us about one of the origins of the reprobation of onanism, as well as one possible way, among many others, for traditional thinking to explain the clinical enigma of depressive syndrome.
(17) (As told in the 1950 World Cup 'final' MBM from And Gazza Misses The Final , written by the excellent Rob Smyth and some other reprobate.)
(18) The Southern blots were reprobed with a cloned fragment of the STA2 glucoamylase gene of S. diastaticus.
(19) If the trailer is any indication , this final series will see the various gangsters and reprobates of the prohibition era attempting to legitimise themselves as businessmen.
(20) Repeated cycles of oligomer probe synthesis and subsequent reprobing permit rapid sequence walking along the genome.