What's the difference between mischarge and wrongly?
Mischarge
Definition:
(v. t.) To charge erroneously, as in account.
(n.) A mistake in charging.
Example Sentences:
(1) These interpretations have been extended to other mischarging systems: valylation of yeast tRNAPhE by yeast valyl-tRNA synthetase and mischarging of tRNAfMet and tRNA2Val from yeast by yeast phenylalanyl-tRNA synthetase.
(2) The mutant enzymes mischarge supF tRNA(Tyr), with glutamine, to varying degrees depending on the polarity of the side chain introduced but apparently not depending on the size or shape of the side chain.
(3) In this paper, we screened temperature sensitive mutants of E. coli in which the mischarging suppression was abolished even at the permissive temperature.
(4) The mischarging sites in Su+2 glutamine tRNA locate in the newly detected region of tRNA, differing from the previous case of Su+3 tyrosine or Su+7 tryptophan tRNAs.
(5) However, in contrast to the wild-type tRNA(Asp) transcript, the 5' extended molecule presents a reduced capacity to be mischarged by arginyl-tRNA synthetase, suggesting the existence of different structural requirements in aspartyl- and arginyl-tRNA synthetases for tRNA(Asp) recognition.
(6) Although unmodified tRNA(Asp) is charged with aspartate as efficiently as the modified native tRNA, it is mischarged with arginine with considerably increased efficiency.
(7) Kinetic analysis of the mischarging revealed that dimethyl sulfoxide stimulated the misacylation by affecting the maximum velocity.
(8) One such error involves a mischarging step in which the aspartic acid side-chain beta-carboxyl group is linked to the tRNA(Asp) instead of the main chain alpha-carboxyl group.
(9) No lactonisation nor mischarged tRNALeu is detectable.
(10) It is shown that during the ATP pyrophosphatase reaction: (a) IRS forms an IRS-Val-AMP complex; (b) the turnover number of the ATP pyrophosphatase reaction is the same at the rate constant for the transfer of isoleucine from IRS-Ile-AMP to tRNAIle over a wide range of temperature and pH; (c) mischarged Val-tRNAIle is hydrolyzed by IRS with a turnover number of 10 s-1 at pH 7.78 and 25 degrees C, compared with a value of 1.2 s-1 for the transfer of isoleucine from IRS-Ile-AMP to tRNA or for the ATP pyrophosphatase reaction.
(11) The ternary complex containing the mischarged initiator tRNA fVal-tRNAfMet displays greater resistance to the IF-3-induced destabilization than the complex containing fVal-tRNAVal.
(12) In order to select the mischarging mutants of Su+2 glutamine tRNA, auxotrophic amber mutants of E. coli K12 which cannot be suppressed particularly by Su+2 were screened.
(13) This result contrasts with the reduced rates observed in tRNA mischarging, and suggests that the viral RNA could be easily aminoacylated in vivo.
(14) We conclude that the mutant tRNAs still accept mostly glutamine, but can accept tryptophan in an extent for mischarging suppression.
(15) The role of the anticodon and discriminator base in aminoacylation of tRNAs with tryptophan has been explored using a recently developed in vivo assay based on initiation of protein synthesis by mischarged mutants of the Escherichia coli initiator tRNA.
(16) Two of the methods utilize the mischarging ability of the synthetases under special conditions of low salt concentration and presence of organic solvents.
(17) Although the isoleucyl-tRNA synthetase from Escherichia coli (IRS) does not catalyze the overall mischarging of tRNAIle with valine, it does undergo the first step of the reaction, the formation of an IRS-Val-AMP complex.
(18) Mischarging of the activated CCA-halves of tRNASer1,2 (yeast) and tRNAPhe (yeast) with phenylalanine and serine, respectively, was not observed.
(19) The mutant, called glnS7, has an Asp----Asn change, and studies with the purified glnS7 gene product show it may mischarge a number of presumably different tRNAs.
(20) Furthermore, and as in correct systems, we found that during the mischarging of tRNAfMet one ATP is hydrolyzed per tRNA charged with valine.
Wrongly
Definition:
(adv.) In a wrong manner; unjustly; erroneously; wrong; amiss; as, he judges wrongly of my motives.
Example Sentences:
(1) In this book, he dismisses Freud's idea of penis envy - "Freud got it spectacularly wrong" - and said "women don't envy the penis.
(2) But this is to look at the outcomes in the wrong way.
(3) It is not that the concept of food miles is wrong; it is just too simplistic, say experts.
(4) "But this is not all Bulgarians and gives a totally wrong picture of what the country is about," she sighed.
(5) No malignant tumour failed to be diagnosed (100% reliable), the anatomopathological examination of specimens in benign conditions was never wrong (100% reliable).
(6) The Bible treats suicide in a factual way and not as wrong or shameful.
(7) "That attracted all the wrong sorts for a few years, so the clubs put their prices up to keep them out and the prices never came down again."
(8) More than half of carers said they were neglecting their own diet as a result of their caring responsibilities, while some said they were eating the wrong things because of the stress they are under and more than half said they had experienced problems with diet and hydration.
(9) A final experiment confirmed a prediction from the above theory that when recalling the original sequence, omissions (recalling no word) will decrease and transpositions (giving the wrong word) will increase as noise level increases.
(10) Other details showed the wrong patient undergoing a heart procedure, and the wrong patient given an invasive colonoscopy to check their bowel.
(11) Mulholland and others have tried to portray the Leeds case in terms of right or wrong.
(12) And of course, as the articles are shared far and wide across the apparently much-hated web, they become gospel to those who read them and unfortunately become quasi-religious texts to musicians of all stripes who blame the internet for everything that is wrong with their careers.
(13) And I was a little surprised because I said: ‘Doesn’t sound like he did anything wrong there.’ But he did something wrong with respect to the vice-president and I thought that was not acceptable.” So that’s clear.
(14) The fitting element to a Cabrera victory would have been thus: the final round of the 77th Masters fell on the 90th birthday of Roberto De Vicenzo, the great Argentine golfer who missed out on an Augusta play-off by virtue of signing for the wrong score.
(15) "I don't think that people are waiting for the wrong solution."
(16) I can’t hear those wrong notes any more,” she says.
(17) "This crowd of charlatans ... look for one little thing they can say is wrong, and thus generalise that the science is entirely compromised."
(18) Eleven women have died in India and dozens more are in hospital, with 20 listed as critically ill, after a state-run mass sterilisation campaign went horribly wrong.
(19) in horses is imputed to the small numbers of people involved in the work, to the conservation of the authorities responsible for breeding, to the wrong choice of stallions for A.I.
(20) The Sun editor also said his newspaper was wrong to use the word "tran" in a headline to describe a transexual, saying that he felt that "I don't know this is our greatest moment, to be honest".