(v. t.) To make less severe, intense, harsh, rigorous, painful, etc.; to soften; to meliorate; to alleviate; to diminish; to lessen; as, to mitigate heat or cold; to mitigate grief.
(v. t.) To make mild and accessible; to mollify; -- applied to persons.
Example Sentences:
(1) In mitigation, Gareth Jones, defending, said: "The first comment [he] wrote was in relation to Fabrice Muamba.
(2) The small numbers involved (29) and the difficulties in matching subjects may have mitigated against demonstrating a statistically significant difference between the two groups.
(3) The news comes one week after Marshall announced, in an email to staff, that there would be a shift in research priorities, away from understanding the nature of climate change, and towards adaptation and mitigation.
(4) Golding said the government would not soften its stance on drug trafficking and it intended to use a proportion of revenues from its licensing authority to support a public education campaign to discourage pot-smoking by young people and mitigate public health consequences.
(5) This has improved the capacity of the neuroanaesthetist to mitigate the inevitable fluctuations which occur and prevent their ill effects.
(6) The survey was designed to assess whether these individuals followed the 1986 EPA guidelines for follow-up testing and mitigation.
(7) Despite doing a study of mitigation options, no decisions are planned until 2012.
(8) The level of disruption to services will vary widely and depend on the number of staff joining the strike, the mitigating impact of the NHS’s contingency planning and how many patients need acute care, such as A&E care or surgery.
(9) Aid workers have warned that children in the disaster zone left by typhoon Haiyan are particularly vulnerable, as they set up child-focused services to mitigate the impact.
(10) Regression analyses suggested that such aggression-inhibitory effects of an apology were mediated by impression improvement, emotional mitigation, and reduction in desire for an apology within the victims.
(11) At present, however, technical and economic factors combine to mitigate against MRI.
(12) The IPCC is charged with providing a scientific, balanced assessment about what's known and what's known about climate change There are lots of organisations ringing bells The IPCC is more like a belltower, which people can climb up to get a clear view 8.41am BST Al Gore , the former US vice-president and winner of the Nobel peace prize for his work on climate change , has responded to the IPCC report by saying it shows the need for a switch to low carbon sources of energy (note his emphasis is on mitigation, i.e.
(13) Potential strategies to avoid the precipitating antigen antibody reaction or to mitigate the resulting effector cascade are described.
(14) The results of this study serve to mitigate concern over the possible carcinogenicity of MDA in the diet, since less than 10% of the MDA in several foods containing highly unsaturated fatty acids was found in the free form.
(15) The deputy president, William Ruto, said it is now up to the developed world to mitigate the fallout, suggesting that other countries including the UK should resettle the refugees who could soon be kicked out of Kenya.
(16) Application of the formula in 3 patients with the juvenile CLF, the M. Batten-Spielmeyer-Vogt, resulted in a mitigated course of the disease.
(17) "The one thing that we have come up with is the importance of adaptation and mitigation choices.
(18) There is an art as well as a science to accurately presenting devastating facts while mitigating potentially unnecessary emotional damage.
(19) The issue is the capacity of the law to mitigate it.
(20) Delivery of oxygenated autologous blood to the myocardium at risk during inflation may help mitigate this ischemia.
Modulate
Definition:
(v. t.) To form, as sound, to a certain key, or to a certain portion.
(v. t.) To vary or inflect in a natural, customary, or musical manner; as, the organs of speech modulate the voice in reading or speaking.
(v. i.) To pass from one key into another.
Example Sentences:
(1) The variation in thickness of the LLFL may modulate the species causing damage to the cells below it.
(2) These included bringing in the A* grade, reducing the number of modules from six to four, and a greater attempt to assess the whole course at the end.
(3) The vascular endothelium is capable of regulating tissue perfusion by the release of endothelium-derived relaxing factor to modulate vasomotor tone of the resistance vasculature.
(4) Quantitative determinations indicate that the amount of PBG-D mRNA is modulated both by the erythroid nature of the tissue and by cell proliferation, probably at the transcriptional level.
(5) Gel filtration of the 40,000 rpm supernatant fraction of a homogenate of rat cerebral cortex on a Sepharose 6B column yielded two fractions: fraction II with the "Ca(2+) plus Mg(2+)-dependent" phosphodiesterase activity and fraction III containing its modulator.
(6) This modulation results from repetitive, alternating bursts of excitatory and inhibitory postsynaptic potentials, which are caused at least in part by synaptic feedback to the command neurons from identified classes of neurons in the feeding network.
(7) Modulation of the voltage-gated K+ conductance in T-lymphocytes by substance P was examined.
(8) Thus, human bronchial epithelial cells can express the IL-8 gene, with expression in response to the inflammatory mediator TNF regulated mainly at the transcriptional level, and with elements within the 5'-flanking region of the gene that are directly or indirectly modulated by the TNF signal.
(9) This study examines the role of sex hormones in modulating the expression of autoimmunity in NZB x NZW F1 mice.
(10) More needs to be known about the direct and indirect modulation of cytokine production by cyclosporin A in connective tissues, in order to understand its potential value in clinical disorders.
(11) We suggest that neuronal PACAP may serve to modulate motor activity and secretion in the lower esophageal sphincter region.
(12) Furthermore, modulation of the assay by prostaglandin E2 (PGE2) was used to increase its sensitivity.
(13) Masking experiments are demonstrated for electrical frequency-modulated tone bursts from 1,000 to 10,000 cps and from 10,000 to 1,000 cps with superimposed clicks.
(14) From these results, BM-Eo are naive and seem to be a good indicator for eosinophilotaxis and its modulation.
(15) Administration of modulators in combinations of threes resulted in still further reduction of tumor incidences to 22.2% (SS + MC + AA), 19.2% (SS + MC + RA), 16% (MC + AA + RA) and 23.1% (AA + RA + SS).
(16) These findings suggest that activation of protein kinase C may act as a feedback inhibitor to modulate ligand-mediated increases in [Ca2+]i.
(17) These studies demonstrate that vWF interaction with GP Ib may be modulated by botrocetin binding to a discontinuous site located within residues 539-643.
(18) This contrasts sharply with the reduction in both the frequency and surface area of sensory neuron active zones that accompanies long-term habituation, and suggests that modulation of active zone number and size may be an anatomical correlate that lies in the long-term domain.
(19) Thus, it appears that the modulation of the phosphorylation of these cytosolic proteins represents an essential step in the regulation of T lymphocyte activation.
(20) Energy conformational calculations on these compounds were also carried out using the empirical energy program called MOLMEC, in order to better understand how the 4-R substituents modulate receptor binding affinities and efficacies.