(a.) Kept within due bounds; observing reasonable limits; not excessive, extreme, violent, or rigorous; limited; restrained
(a.) Limited in quantity; sparing; temperate; frugal; as, moderate in eating or drinking; a moderate table.
(a.) Limited in degree of activity, energy, or excitement; reasonable; calm; slow; as, moderate language; moderate endeavors.
(a.) Not extreme in opinion, in partisanship, and the like; as, a moderate Calvinist.
(a.) Not violent or rigorous; temperate; mild; gentle; as, a moderate winter.
(a.) Limited as to degree of progress; as, to travel at moderate speed.
(a.) Limited as to the degree in which a quality, principle, or faculty appears; as, an infusion of moderate strength; a man of moderate abilities.
(a.) Limited in scope or effects; as, a reformation of a moderate kind.
(n.) One of a party in the Church of Scotland in the 18th century, and part of the 19th, professing moderation in matters of church government, in discipline, and in doctrine.
(v. t.) To restrain from excess of any kind; to reduce from a state of violence, intensity, or excess; to keep within bounds; to make temperate; to lessen; to allay; to repress; to temper; to qualify; as, to moderate rage, action, desires, etc.; to moderate heat or wind.
(v. t.) To preside over, direct, or regulate, as a public meeting; as, to moderate a synod.
(v. i.) To become less violent, severe, rigorous, or intense; as, the wind has moderated.
(v. i.) To preside as a moderator.
Example Sentences:
(1) The newborn with critical AS typically presents with severe cardiac failure and the infant with moderate failure, whereas children may be asymptomatic.
(2) One hour after direct mechanical cardiomassage (DMCM) a moderately pronounced edema of the intercellular spaces in the basal compartment of the seminiferous epithelium, normal content of lactate and succinate dehydrogenases, and a certain decrease in the activity of glucose-6-phosphate dehydrogenases and NAD- and NADP-diaphorases were noted.
(3) In the surface epithelial cells, the basolateral cell surface showed moderate enzymatic activity.
(4) Histological studies showed that the resulting pancreatitis was usually mild to moderate, being severe only in association with sepsis.
(5) Systemic corticosteroids (i.e., prednisone, prednisolone or methylprednisolone) have improved the survival rate of patients with moderate and severe ulcerative colitis.
(6) We report the results of a double-blind, placebo-controlled trial of acitretin (Soriatane) in 15 patients with moderate to severe psoriasis.
(7) Furthermore echography revealed a collateral subperiosteal edema and a moderate thickening of extraocular muscles and bone periostitis, a massive swelling of muscles and bone defects in subperiosteal abscesses as well as encapsulated abscesses of the orbit and a concomitant retrobulbar neuritis in orbital cellulitis.
(8) TR was classified as follows: severe (massive systolic opacification and persistence of the microbubbles in the IVC for at least 20 seconds); moderate (moderate systolic opacification lasting less than 20 seconds); mild (slight systolic opacification lasting less than 10 seconds); insignificant TR (sporadic appearance of the contrast medium into the IVC).
(9) Mild swallowing difficulties occurred in 18 patients (39%), moderate dysfunction in 23 (50%), and severe dysfunction in five (11%).
(10) The radius is estimated to be around 1.7 nm, which shows a moderate degree of hydration.
(11) The deep cerebellar nuclei were moderately labeled at birth and gradually decreased in density thereafter.
(12) The epithelium of Brunner's gland stained intensely with Ricinus communis agglutinin-I (RCA-I), succinylated-WGA (S-WGA) and wheat-germ agglutinin (WGA), moderately with Bandeirea simplicifolia agglutinin-I (BS-I), Concanavalia ensiformis agglutinin (Con A) peanut agglutinin (PNA) and Ulex europaeus agglutinin-I (UEA-I) and occasionally with Dolichos biflorus agglutinin (DBA), Lens culinaris agglutinin (LCA) and soybean agglutinin (SBA).
(13) 2-(4'-Isobutylphenyl)propionic acid, ibuprofen, is an antiinflammatory agent which possesses moderate platelet aggregation inhibitory activity.
(14) Electroretinographic (ERG), morphometric and biochemical studies on retinas from monkeys or rats reveal that moderate level developmental lead (Pb) exposure produces long-term selective rod deficits and degeneration.
(15) The remaining 33 sera (13.3 per cent) were classified as low, moderate or strong positives.
(16) The agriculture ministry raised the risk level of the virus spreading from moderate to high on Tuesday across the country, at a crucial time for the industry.
(17) The role of blood acetylcholinesterase in moderating the effects of organophosphate challenge in rats was tested.
(18) C. tropicalis was grown in a medium containing Brij 35, resulting in the induction of a moderate number of medium-sized peroxisomes.
(19) Data from 579 medical students from the classes of 1979-80 through 1983-84 attending a midwestern medical college were analyzed via moderated multiple regression.
(20) Altering the time of PMA exposure demonstrated that PMA inhibited chondrocyte phenotypic expression, rather than cell commitment: early (0-48 h) exposure to PMA (during chondrocytic commitment in vitro) had little inhibitory effect on the staining index, whereas, exposure from 49-96 h (presumably post-commitment) and 0-96 h had moderate and strong inhibitory effects, respectively, on cartilage synthesis.
Significant
Definition:
(a.) Fitted or designed to signify or make known somethingl having a meaning; standing as a sign or token; expressive or suggestive; as, a significant word or sound; a significant look.
(a.) Deserving to be considered; important; momentous; as, a significant event.
(n.) That which has significance; a sign; a token; a symbol.
Example Sentences:
(1) Once treatment began, no significant changes occurred in Group 1, but both PRA and A2 rose significantly in Groups 2 and 3.
(2) However, patients with GGBHS were significantly older (P less than .05).
(3) In each sheep there was a significant negative correlation between the glucose and corticosteroid concentrations in both maternal and fetal plasma, and there were positive correlations between the maternal and fetal plasma concentrations of glucose, and between the glucose and fructose concentrations of fetal plasma.
(4) Such a decrease significantly biased survival (p = 0.001).
(5) This may have significant consequences for people’s health.” However, Prof Peter Weissberg, medical director of the British Heart Foundation, which funded the work, said medical journals could no longer be relied on to be unbiased.
(6) It is supposed that delta-sleep peptide along with other oligopeptides is one of the factors determining individual animal resistance to emotional stress, which is supported by significant delta-sleep peptide increase in hypothalamus in stable rats.
(7) However, when first trimester specimens were analyzed, the direct-product measurements were significantly larger than the corresponding 3H2O assay results.
(8) The Na+ ionophore, gramicidin, had a small but significant inhibitory effect on Na(+)-dependent KG uptake, demonstrating that KG uptake was not the result of an intravesicular positive Na+ diffusion potential.
(9) Propranolol resulted in a significantly lower mean hourly, mean 24 h and minimum heart rate.
(10) In some other countries the patient-to-nurse ratio was significantly smaller.
(11) The findings indicate that there is still a significant incongruence between the value structure of most family practice units and that of their institutions but that many family practice units are beginning to achieve parity of promotion and tenure with other departments in their institutions.
(12) The significance of minor increases in the serum creatinine level must be recognized, so that modifications of drug therapy can be made and correction of possibly life-threatening electrolyte imbalances can be undertaken.
(13) The process of sequence rearrangement appears to be a significant part of the evolution of the genome and may have a much greater effect on the evolution of the phenotype than sequence alteration by base substitution.
(14) The low affinity of several N1-alkylpyrroleethylamines suggests that the benzene portion of the alpha-methyltryptamines is necessary for significant affinity.
(15) During control, no significant difference between systolic fluctuation (delta Pa) and pleural swings (delta Ppl) was found.
(16) Urinary ANF immunoreactivity was significantly enhanced by candoxatril in both groups (P less than 0.05 and P less than 0.01 in groups 1 and 2, respectively), with a more pronounced effect evident at the higher dose (P less than 0.01).
(17) Both lymph flow from cannulated pancreatico-duodenal lymphatics and intralymphatic pressure in the non-transected ones increased significantly.
(18) We conclude that the priming effect is not a clinically significant phenomenon during natural pollen exposure in allergic rhinitis patients.
(19) This study examined the [3H]5-HT-releasing properties of 3,4-methylenedioxymethamphetamine (MDMA) and related agents, all of which cause significant release of [3H]5-HT from rat brain synaptosomes.
(20) However, the degree of sedation caused by diphenhydramine was significantly greater than that caused by cimetidine (P = .0001).