(a.) Kept within due bounds; observing reasonable limits; not excessive, extreme, violent, or rigorous; limited; restrained
(a.) Limited in quantity; sparing; temperate; frugal; as, moderate in eating or drinking; a moderate table.
(a.) Limited in degree of activity, energy, or excitement; reasonable; calm; slow; as, moderate language; moderate endeavors.
(a.) Not extreme in opinion, in partisanship, and the like; as, a moderate Calvinist.
(a.) Not violent or rigorous; temperate; mild; gentle; as, a moderate winter.
(a.) Limited as to degree of progress; as, to travel at moderate speed.
(a.) Limited as to the degree in which a quality, principle, or faculty appears; as, an infusion of moderate strength; a man of moderate abilities.
(a.) Limited in scope or effects; as, a reformation of a moderate kind.
(n.) One of a party in the Church of Scotland in the 18th century, and part of the 19th, professing moderation in matters of church government, in discipline, and in doctrine.
(v. t.) To restrain from excess of any kind; to reduce from a state of violence, intensity, or excess; to keep within bounds; to make temperate; to lessen; to allay; to repress; to temper; to qualify; as, to moderate rage, action, desires, etc.; to moderate heat or wind.
(v. t.) To preside over, direct, or regulate, as a public meeting; as, to moderate a synod.
(v. i.) To become less violent, severe, rigorous, or intense; as, the wind has moderated.
(v. i.) To preside as a moderator.
Example Sentences:
(1) The newborn with critical AS typically presents with severe cardiac failure and the infant with moderate failure, whereas children may be asymptomatic.
(2) One hour after direct mechanical cardiomassage (DMCM) a moderately pronounced edema of the intercellular spaces in the basal compartment of the seminiferous epithelium, normal content of lactate and succinate dehydrogenases, and a certain decrease in the activity of glucose-6-phosphate dehydrogenases and NAD- and NADP-diaphorases were noted.
(3) In the surface epithelial cells, the basolateral cell surface showed moderate enzymatic activity.
(4) Histological studies showed that the resulting pancreatitis was usually mild to moderate, being severe only in association with sepsis.
(5) Systemic corticosteroids (i.e., prednisone, prednisolone or methylprednisolone) have improved the survival rate of patients with moderate and severe ulcerative colitis.
(6) We report the results of a double-blind, placebo-controlled trial of acitretin (Soriatane) in 15 patients with moderate to severe psoriasis.
(7) Furthermore echography revealed a collateral subperiosteal edema and a moderate thickening of extraocular muscles and bone periostitis, a massive swelling of muscles and bone defects in subperiosteal abscesses as well as encapsulated abscesses of the orbit and a concomitant retrobulbar neuritis in orbital cellulitis.
(8) TR was classified as follows: severe (massive systolic opacification and persistence of the microbubbles in the IVC for at least 20 seconds); moderate (moderate systolic opacification lasting less than 20 seconds); mild (slight systolic opacification lasting less than 10 seconds); insignificant TR (sporadic appearance of the contrast medium into the IVC).
(9) Mild swallowing difficulties occurred in 18 patients (39%), moderate dysfunction in 23 (50%), and severe dysfunction in five (11%).
(10) The radius is estimated to be around 1.7 nm, which shows a moderate degree of hydration.
(11) The deep cerebellar nuclei were moderately labeled at birth and gradually decreased in density thereafter.
(12) The epithelium of Brunner's gland stained intensely with Ricinus communis agglutinin-I (RCA-I), succinylated-WGA (S-WGA) and wheat-germ agglutinin (WGA), moderately with Bandeirea simplicifolia agglutinin-I (BS-I), Concanavalia ensiformis agglutinin (Con A) peanut agglutinin (PNA) and Ulex europaeus agglutinin-I (UEA-I) and occasionally with Dolichos biflorus agglutinin (DBA), Lens culinaris agglutinin (LCA) and soybean agglutinin (SBA).
(13) 2-(4'-Isobutylphenyl)propionic acid, ibuprofen, is an antiinflammatory agent which possesses moderate platelet aggregation inhibitory activity.
(14) Electroretinographic (ERG), morphometric and biochemical studies on retinas from monkeys or rats reveal that moderate level developmental lead (Pb) exposure produces long-term selective rod deficits and degeneration.
(15) The remaining 33 sera (13.3 per cent) were classified as low, moderate or strong positives.
(16) The agriculture ministry raised the risk level of the virus spreading from moderate to high on Tuesday across the country, at a crucial time for the industry.
(17) The role of blood acetylcholinesterase in moderating the effects of organophosphate challenge in rats was tested.
(18) C. tropicalis was grown in a medium containing Brij 35, resulting in the induction of a moderate number of medium-sized peroxisomes.
(19) Data from 579 medical students from the classes of 1979-80 through 1983-84 attending a midwestern medical college were analyzed via moderated multiple regression.
(20) Altering the time of PMA exposure demonstrated that PMA inhibited chondrocyte phenotypic expression, rather than cell commitment: early (0-48 h) exposure to PMA (during chondrocytic commitment in vitro) had little inhibitory effect on the staining index, whereas, exposure from 49-96 h (presumably post-commitment) and 0-96 h had moderate and strong inhibitory effects, respectively, on cartilage synthesis.
Tolerable
Definition:
(a.) Capable of being borne or endured; supportable, either physically or mentally.
(a.) Moderately good or agreeable; not contemptible; not very excellent or pleasing, but such as can be borne or received without disgust, resentment, or opposition; passable; as, a tolerable administration; a tolerable entertainment; a tolerable translation.
Example Sentences:
(1) within 12 h of birth followed by similar injections every day for 10 consecutive days and then every second day for a further 8 weeks, with mycoplasma broth medium (tolerogen), to induce immune tolerance.
(2) No differences between the two substances were observed with respect to side effects and general tolerability.
(3) This treatment is usually well tolerated but not devoid of systemic effects.
(4) Well tolerated from the clinical and laboratory points of view, it proved remarkably effective.
(5) To estimate the age of onset of these differences, and to assess their relationship to abdominal and gluteal adipocyte size, we measured adiposity, adipocyte size, and glucose and insulin concentrations during a glucose tolerance test in lean (less than 20% body fat), prepubertal children from each race.
(6) Although temazepam was effective for maintaining sleep with short-term use, there was rapid development of tolerance for this effect with intermediate-term use.
(7) testosterone, fentanyl, nicotine) may ultimately be administered in this way, important questions pertaining to pharmacology (tolerance), toxicity (irritation, sensitisation) and dose sufficiency (penetration enhancement) remain.
(8) There were no biochemical or haematological abnormalities caused by prazosin but on continued therapy 16 patients developed tolerance to its effect.
(9) Characerization of further parameters such as relative susceptibility to tolerance induction and relative degree of specificity was not possible with the use of KLH as the antigen.
(10) Because of these different direct and indirect actions, a sudden cessation of sinus node activity or sudden AV block may result in the diseased heart in a prolonged and even fatal cardiac standstill, especially if the tolerance to ischemia of other organs (notably the brain) is decreased.
(11) Efficacy and tolerability of perorally administered desmopressin were evaluated in 12 adult patients suffering from central diabetes insipidus.
(12) This suggests that both blood transfusion and allograft are required for IL2 suppression and that this suppression may be related to the heart tolerance.
(13) At present, ACE inhibitors are preferred because they are usually better tolerated than conventional vasodilators and are clinically more effective.
(14) Changes in pain tolerance after administration of differently labelled placebos were studied by measuring the reaction time after a cold stimulus.
(15) TK1 showed the most restricted substrate specificity but tolerated 3'-modifications of the sugar ring and some 5-substitutions of the pyrimidine ring.
(16) Provided that adequate reflection is given and the appropriate moment chosen, it is well tolerated and provides all the necessary information.
(17) After large bowel removal, there was impaired glucose tolerance and attenuated plasma insulin secretion.
(18) Cardiac pump function is not affected, even in patients with ventricular dysfunction or heart failure, in whom chronic oral administration of the drug is well tolerated.
(19) These agents have been well-tolerated and generally produce a high incidence of sustained improvements in neutrophil counts and marrow morphology, although hemoglobin and platelet counts have generally not been altered.
(20) The above treatment is tolerated well and no serious side effects have been observed.